Results 61 to 70 of about 11,647 (179)

Function and Modulation of Sphingosine-1-Phosphate Receptors in the Central Nervous System

Receptors
Sphingolipids, first discovered in 1874 by Johann Thudicum, are among the eight recognized classes of lipids and are present in essentially all plants, animals, and fungi, as well as some viruses and prokaryotes. In mammals, sphingolipids are enriched in
Elizabeth Gulliksen, Sriya Darsi, Ladan Haidarbaigi, Lucas J. Codispoti, Devam Purohit, Ashley Jung, Aishwarya Chilamula, Jason Newton   +7 more
doaj   +1 more source

Opposing roles of DGAT‐mediated lipid droplet biogenesis in the regulation of ferroptosis sensitivity

The FEBS Journal, Volume 293, Issue 15, Page 4508-4532, August 2026.
Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump, Leja Perne, Špela Koren, Eva Jarc Jovičić, Nastja Feguš, Carina Pinto Kozmus, Michele Wölk, Kristyna Brejchova, Maria Fedorova, Ondrej Kuda, Toni Petan   +10 more
wiley   +1 more source

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

The FEBS Journal, Volume 293, Issue 15, Page 4554-4577, August 2026.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo, Lorenza Driul, Vanessa Tolotto, Eros Di Giorgio, Luigi E. Xodo   +4 more
wiley   +1 more source

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, Volume 13, Issue 41, 22 July 2026.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source

Investigations of the lysophospholipid composition of human neutrophils under different stimulation conditions by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry [PDF]

Journal of the Serbian Chemical Society, 2002
Matrix-assisted laser desorption / ionization time-of-flight mass spectrometry (MALDI-TOF MS) is usually used for the analyses of proteins, carbohydrates and oligonucleotides.
JURGEN ARNHOLD, KLAUS ARNOLD, MATTHIAS MULLER, JURGEN SCHILLER, MARIJANA PETKOVIC   +4 more
doaj  

Phosphorus Deficiency Alters Nutrient Accumulation Patterns and Grain Nutritional Quality in Rice

Agronomy, 2016
The accumulation of biomass and mineral nutrients during the post-anthesis period was investigated in field-grown rice plants cultivated in phosphorus (P)-sufficient vs. P-deficient soil.
Terry J. Rose, Tobias Kretzschmar, Lei Liu, Graham Lancaster, Matthias Wissuwa   +4 more
doaj   +1 more source

Effect of Chitooligosaccharides‐Combination Fortified Noodles Intervention on Visceral Adiposity and Serum Metabolites in a High‐Risk Occupational Cohort of Young Seafarers

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
In a 4‐week self‐controlled trial of 73 young seafarers, consumption of chitooligosaccharides‐combination fortified noodles every other day significantly reduced visceral fat area, waist circumference, serum leptin, and LDL‐C, and elevated skeletal muscle index, without altering body weight.
Zhongbo Bian, Jiaming Wang, Yi Lu, YanYing Yao, Xiangru Feng, Xinjie Zhou, Xiao guo Ji, Juan Li   +7 more
wiley   +1 more source

Tracking COVID‐19 Severity and Progression Through Amines and Lipid Mediators

Journal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT Coronavirus disease 2019 (COVID‐19) exhibits a broad spectrum of severity, ranging from mild to critical cases. To reduce mortality and costs, tailored early interventions for at‐risk patients are essential. This study elucidates the association between longitudinal metabolomic profiles and COVID‐19 severity and progression.
Melissa Goris, Merys Valdez, Lieke Lamont, Wei Yang, Amy Harms, Naama Karu, Sabine Bos, Jelte Geerlings, Tom Ottenhoff, Roula Tsonaka, Anna HE Roukens, M. Sesmu Arbous, Simone A. Joosten, Thomas Hankemeier, Alida Kindt, In collaboration with BEAT‐COVID group, M.S. Arbous, B.M. van den Berg, S. Cannegieter, C.M. Cobbaert, A. van der Does, J.J.M. van Dongen, J. Eikenboom, M.C.M. Feltkamp, A. Geluk, J.J. Goeman, M. Giera, T. Hankemeier, M.H.M. Heemskerk, P.S. Hiemstra, C.H. Hokke, J.J. Janse, S.P. Jochems, S.A. Joosten, M. Kikkert, L. Lamont, J. Manniën, T.H.M. Ottenhoff, M.R. del Prado, N. Queralt Rosinach, M. Roestenberg, M. Roos, A.H.E. Roukens, H.H. Smits, E.J. Snijder, F.J.T. Staal, L.A. Trouw, R. Tsonaka, A. Verhoeven, L.G. Visser, J.J.C. de Vries, D.J. van Westerloo, J. Wigbers, H.J. van der Wijk, R.C. van Wissen, M. Wuhrer, M. Yazdanbakhsh, M. Zlei   +57 more
wiley   +1 more source

Lipids of mineralizing epiphyseal tissues in the bovine fetus

Journal of Lipid Research, 1968
Because lipids had been consistently detected histologically at sites of new calcification, the lipids of epiphyseal cartilage and bone in various stages of mineralization were examined.
R.E. Wuthier
doaj   +1 more source

Reprogramming lipid metabolism for cognitive restoration in Alzheimer's via PLA2G4E

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 3, July/September 2026.
Abstract INTRODUCTION Growing evidence implicates dysregulated brain lipid metabolism in Alzheimer's disease (AD) pathogenesis, influencing membrane integrity, neuroinflammation, and amyloid beta and tau pathology, thereby representing a promising therapeutic target.
Sara Badesso, María Espelosín, Cristina Alonso, Alejandro Montilla, Maria Collantes, Mar Cuadrado‐Tejedor, Ana García‐Osta   +6 more
wiley   +1 more source