Results 21 to 30 of about 929 (218)
Antioxidant and anti-inflammatory properties of the methanolic extract of Siphonochilus aethiopicus rhizomes [PDF]
Journal of HerbMed Pharmacology, 2021 Introduction: Siphonochilus aethiopicus is a medicinal plant widely used in the treatment of many inflammatory conditions such as arthritis. The objective of this study was therefore to evaluate the antioxidant and anti-inflammatory properties of ...
Elize Dadaya +4 more
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Lymphocyte Lysosomes and Lysosomal Enzymes in Chronic Lymphocytic Leukemia [PDF]
Blood, 1973 Abstract Electron microscopic cytochemical and biochemical studies of lysosomal markers have been performed in unstimulated normal and chronic lymphotic leukemia (CLL) lymphocytes. Decreased activities of the lysosomal enzymes acid phosphatase and β-glucuronidase but not of the nonlysosomal enzyme malate dehydrogenase were observed in ...
S D, Douglas +3 more
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Lysosomal Enzymes in Bruised Tissue.
Experimental Biology and Medicine, 1965 SummaryLysosomal DNase, RNase, β-glucuronidase and β-galactosidase activities in experimentally inflicted poultry breast bruises increased by the second day post contusion, reached a maximum between the third and fifth day and then declined toward normal as the bruises showed gross morphological healing.
W E, BROWN, M K, HAMDY
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Progranulin acts as a shared chaperone and regulates multiple lysosomal enzymes
Genes and Diseases, 2017 Multifunctional factor progranulin (PGRN) plays an important role in lysosomes, and its mutations and insufficiency are associated with lysosomal storage diseases, including neuronal ceroid lipofuscinosis and Gaucher disease (GD).
Jinlong Jian +2 more
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Golgi defect as a major contributor to lysosomal dysfunction
Frontiers in Cell and Developmental BiologyThe Golgi apparatus plays a crucial role in lysosome biogenesis and the delivery of lysosomal enzymes, essential for maintaining cellular homeostasis and ensuring cell survival. Deficiencies in Golgi structure and function can profoundly impact lysosomal
Sarah R. Akaaboune, Yanzhuang Wang
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Lysosomal hydrolases, from waste-bags effectors to essential multipurpose enzymes in liver fibrosis
Exploration of Digestive Diseases, 2023 Lysosomal hydrolases were once considered effectors of the waste disposal system of the cell, the endo-lysosomal system. However, they are now recognized as highly selective enzymes, which can modulate the function of several substrates, contributing to ...
Paloma Ruiz-Blázquez +2 more
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Dose-Response, 2014 Present communication reports the effects of environmentally available, low doses of tetra chloro di benzo-p-dioxin (2,3,7,8 TCDD) to lysosomal enzymes in mice liver.
Jyoti Jigyasi, Rahul Kundu
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Biology Open, 2015 The lysosomal enzyme receptor protein (LERP) of Drosophila melanogaster is the ortholog of the mammalian cation-independent mannose 6-phosphate (Man 6-P) receptor, which mediates trafficking of newly synthesized lysosomal acid hydrolases to lysosomes ...
Medina Hasanagic +5 more
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Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Renal Tubular Dysfunction with Valproate and CBZ
Pediatric Neurology Briefs, 1999 Renal tubular function in epileptic children receiving antiepileptic drugs was evaluated by measurement of lysosomal enzymes at Istanbul University, Turkey.
J Gordon Millichap
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