Results 41 to 50 of about 686,065 (200)

Hydrolysis of phospholipids by a lysosomal enzyme

Journal of Lipid Research, 1967
The phospholipid-hydrolyzing activity of rat liver lysosomes has been studied. These lysosomes contain a phospholipase that cleaves both fatty acid ester linkages of lecithin and of phosphatidyl ethanolamine and releases free fatty acids from both positional isomers of lysolecithin.
A. Mellors, A.L. Tappel
openaire   +3 more sources

The Abnormalities of Lysosomal Enzymes in Mucopolysaccharidoses [PDF]

European Journal of Biochemistry, 1968
The activity of acid hydrolases on 13 substrates has been measured in the liver of normal human subjects and of 32 patients with various forms of mucopolysaccharidoses. The most important abnormalities may be summarized as follows: In 3 patients, there was a complete absence of α‐fucosidase and an excess of fucose in the mucopolysaccharide fraction ...
F, Van Hoof, H G, Hers
openaire   +2 more sources

Low Concentration of a Dioxin (2, 3, 7, 8 TCDD) Affects the Glycosidases and Acid Phosphatase Activity in Mice Hepatocytes

Dose-Response, 2014
Present communication reports the effects of environmentally available, low doses of tetra chloro di benzo-p-dioxin (2,3,7,8 TCDD) to lysosomal enzymes in mice liver.
Jyoti Jigyasi, Rahul Kundu
doaj   +1 more source

The lysosomal enzyme receptor protein (LERP) is not essential, but is implicated in lysosomal function in Drosophila melanogaster

Biology Open, 2015
The lysosomal enzyme receptor protein (LERP) of Drosophila melanogaster is the ortholog of the mammalian cation-independent mannose 6-phosphate (Man 6-P) receptor, which mediates trafficking of newly synthesized lysosomal acid hydrolases to lysosomes ...
Medina Hasanagic, Eline van Meel, Shan Luan, Rajeev Aurora, Stuart Kornfeld, Joel C. Eissenberg   +5 more
doaj   +1 more source

Renal Tubular Dysfunction with Valproate and CBZ

Pediatric Neurology Briefs, 1999
Renal tubular function in epileptic children receiving antiepileptic drugs was evaluated by measurement of lysosomal enzymes at Istanbul University, Turkey.
J Gordon Millichap
doaj   +1 more source

Dataset and standard operating procedure for newborn screening of six lysosomal storage diseases: By tandem mass spectrometry

Data in Brief, 2016
In this data article we provide a detailed standard operating procedure for performing a tandem mass spectrometry, multiplex assay of 6 lysosomal enzymes for newborn screening of the lysosomal storage diseases Mucopolysaccharidosis-I, Pompe, Fabry ...
Susan Elliott, Norman Buroker, Jason J. Cournoyer, Anna M. Potier, Joseph D. Trometer, Carole Elbin, Mack J. Schermer, Jaana Kantola, Aaron Boyce, Frantisek Turecek, Michael H. Gelb, C. Ronald Scott   +11 more
doaj   +1 more source

Newborn Screening for Krabbe Disease—Illinois Experience: Role of Psychosine in Diagnosis of the Disease

International Journal of Neonatal Screening, 2021
Population-based newborn screening for Krabbe disease was initiated by measurement of galactocerebrosidase (GALC) activity in the state of Illinois in December 2017.
Khaja Basheeruddin, Rong Shao, Fran Balster, Pearlie Gardley, Laura Ashbaugh   +4 more
doaj   +1 more source

Inhibition by lysosomal enzymes and mannose-6-phosphate of the phosphorylation of the lysosomal enzyme binding receptor protein from monkey brain

, 1989
The lysosomal enzymes β-glucuronidase and α- L - fucosidase and mannose-6-phosphate inhibited the phosphorylation of the lysosomal enzyme binding receptor protein prepared from monkey brain.
Panneerselvam, K., Balasubramanian, A. S.   +1 more
core   +1 more source

Vacuolar (lysosomal) trehalase of Saccharomyces cerevisiae [PDF]

, 1987
In the yeast Saccharomyces cerevisiae the PEP4 gene product, protease A, is responsible for activating all soluble vacuolar (lysosomal) enzymes. These vacuolar enzymes remain inactive in pep4 mutants.
Cotter, David A., Harris, Steven D.
core   +1 more source

Receptor-Mediated Uptake of Lysosomal Enzymes.

, 1981
Studies concerned with the uptake of lysosomal enzymes by human skin fibroblasts suggested the occurrence of a membrane-associated receptor that binds a phosphomannosyl-containing recognition marker common to lysosomal enzymes. The receptor is thought to
Sahagian, Garabed Gary
core   +1 more source