Results 31 to 40 of about 686,065 (200)
Molecules, 2019 We previously reported on a polyhistidine peptide, His16 peptide, as a new cell-penetrating peptide. This peptide is anticipated to be a new carrier for drug delivery systems (DDSs) for targeting intracellular lysosomes because it can transport ...
Taiki Hayashi +3 more
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Characterization and downstream mannose phosphorylation of human recombinant α-L-iduronidase produced in Arabidopsis complex glycan-deficient (cgl) seeds [PDF]
, 2013 This work was supported by a Wellcome Trust award to TMG.Mucopolysaccharidosis (MPS) I is a lysosomal storage disease caused by a deficiency of α-L-iduronidase (IDUA) (EC 3.2.1.76); enzyme replacement therapy is the conventional treatment for this ...
Brooks, Doug +25 more
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Transactions of the Karelian Research Centre of the Russian Academy of Sciences, 2016 The results on the activity of lysosomal hydrolases (proteases (cathepsins) and nucleases) in salmon (Salmo salar L.) underyearlings (0+), 1+ and 2+ parr, and smolts (2+, 3+)from the Indera River (White Sea drainage basin) are reported, testifying their ...
Marina Krupnova +5 more
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Communications Biology, 2021 Calvaresi et al. use hydrogen-deuterium exchange coupled to mass spectrometry to compare the conformational dynamics of the human heat shock protein Hsp70 when free and when associated with liposomes composed of common lysosomal lipids.
Valeria Calvaresi +5 more
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Lysosomal Enzymes in Bruised Tissue.
Experimental Biology and Medicine, 1965 SummaryLysosomal DNase, RNase, β-glucuronidase and β-galactosidase activities in experimentally inflicted poultry breast bruises increased by the second day post contusion, reached a maximum between the third and fifth day and then declined toward normal as the bruises showed gross morphological healing.
W E, BROWN, M K, HAMDY
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Dendritic transport. I. Colchicine stimulates the transport of lysosomal enzymes from cell bodies to dendrites [PDF]
, 1985 Injection of colchicine into the lateral cerebral ventricle of the rat was found to induce a paradoxical translocation of two lysosomal enzymes, dipeptidyl peptidase II (Dpp II) and acid phosphatase, from the soma of neurons to the dendrites. Following a
MC Bundman +9 more
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STUDIES ON THE RELEASE OF LYSOSOMAL ENZYMES FROM KIDNEY LYSOSOMES [PDF]
The Journal of Cell Biology, 1965 Incubation of kidney lysosomes at 37° results in a graded release of lysosomal enzymes. The release of enzyme occurs in two stages. First the enzymes become available to the substrate but remain sedimentable. Later the amount of soluble enzyme increases and eventually is almost equal to that of the available enzyme.
S, Shibko, J, Pangborn, A L, Tappel
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Golgi defect as a major contributor to lysosomal dysfunction
Frontiers in Cell and Developmental BiologyThe Golgi apparatus plays a crucial role in lysosome biogenesis and the delivery of lysosomal enzymes, essential for maintaining cellular homeostasis and ensuring cell survival. Deficiencies in Golgi structure and function can profoundly impact lysosomal
Sarah R. Akaaboune, Yanzhuang Wang
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Lymphocyte Lysosomes and Lysosomal Enzymes in Chronic Lymphocytic Leukemia [PDF]
Blood, 1973 Abstract Electron microscopic cytochemical and biochemical studies of lysosomal markers have been performed in unstimulated normal and chronic lymphotic leukemia (CLL) lymphocytes. Decreased activities of the lysosomal enzymes acid phosphatase and β-glucuronidase but not of the nonlysosomal enzyme malate dehydrogenase were observed in ...
S D, Douglas +3 more
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Antioxidants, 2022 Physical activity has a positive effect on human health and well-being, but intense exercise can cause adverse changes in the organism, leading to the development of oxidative stress and inflammation.
Marta Pawłowska +8 more
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