Results 51 to 60 of about 686,065 (200)
Acid Angiotensinase as a Lysosomal Enzyme
Japanese Circulation Journal, 1969 1. Both acid angiotensinase and calcium-dependent neutral angiotensinase are widely distributed among various tissues of the rat. High activity of acid angiotensinase in such lysosome-rich tissues as kidney, spleen and liver suggests localization of this enzyme in lysosomes. 2. Main angiotensinases in rat liver are concentrated in lysosomal and soluble
MATSUNAGA, MASATO +4 more
openaire +3 more sources
Papain-like peptidases: structure, function, and evolution
Biomolecular Concepts, 2013 Papain-like cysteine peptidases are a diverse family of peptidases found in most known organisms. In eukaryotes, they are divided into multiple evolutionary groups, which can be clearly distinguished on the basis of the structural characteristics of the ...
Novinec Marko, Lenarčič Brigita
doaj +1 more source
High lumenal chloride in the lysosome is critical for lysosome function
eLife, 2017 Lysosomes are organelles responsible for the breakdown and recycling of cellular machinery. Dysfunctional lysosomes give rise to lysosomal storage disorders as well as common neurodegenerative diseases.
Kasturi Chakraborty +2 more
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Release and uptake of lysosomal enzymes : studied in cultured cells [PDF]
, 1980 The purpose of the experimental work described in this thesiswas to investigate some aspects of the release and uptake of lysosomal enzymes. The experiments involved the use of normal human and animal fibroblasts and some other cell types such as ...
Halley, D.J.J. (Dicky)
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Structural insights into mechanisms underlying stabilization of a lysosomal enzyme through protein engineering [PDF]
Structural DynamicsEnzyme replacement therapies (ERTs) have been approved as treatments for several lysosomal storage disorders, which are characterized by deficiency of a single lysosomal enzyme leading to progressive substrate accumulation, perturbing lysosomal function ...
Jennifer E Kung +6 more
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Activities of Proteolytic Lysosomal Enzymes in Blood and Liver of Growing Cattle
, 2003 . The activities of proteolytic lysosomal enzymes were investigated in serum, leucocytes, liver and muscle of German-Holstein heifers. Altogether there were 119 investigations: 19 9 months, 80 12 months and 20 16 months old female young cattle. Lysosomal
L. Panicke +6 more
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Journal of Lipid Research, 2006 Much is now understood concerning the synthesis of prenylated and palmitoylated proteins, but what is known of their metabolic fate? This review details metabolic pathways for the lysosomal degradation of S-fatty acylated and prenylated proteins. Central
Jui-Yun Lu, Sandra L. Hofmann
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ENZYMES OF LYSOSOMAL ORIGIN IN PLASMA OF TWIN NEONATES
, 1993 The levels of some enzymes of lysosomal origin were assayed during days 2 and 5 of life in plasmas from 11 sets of twin neonates and from 25 neonates from single pregnancies (13 of weight appropriate for gestational age and 12 small for their gestational
G. TETTAMANTI +8 more
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Journal of Lipid Research, 2015 Site-1 protease (S1P) cleaves membrane-bound lipogenic sterol regulatory element-binding proteins (SREBPs) and the α/β-subunit precursor protein of the N-acetylglucosamine-1-phosphotransferase forming mannose 6-phosphate (M6P) targeting markers on ...
Sarah Klünder +5 more
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The Hepatocellular Hypoxia Criteria:2’Nitroimidazole Effect on Hepatocyte Carbohydrate Metabolizing Enzymes [PDF]
, 2008 Aim: to understand the 2’-nitroimidazole induced hypoxia and liver cell interaction, we proposed a “Hapatocellular Hypoxia Criteria”.
Rakesh Sharma
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