Results 71 to 80 of about 686,065 (200)
The binding requirements of monkey brain lysosomal enzymes their immobilised receptor protein [PDF]
The lysosomal enzyme binding protein (receptor protein) isolated from monkey brain was immobilised on Sepharose 4B and used to study the binding of brain lysosomal enzymes.
Panneerselvam, K. +2 more
core
Currently available enzyme replacement therapies for lysosomal storage diseases are limited in their effectiveness due in part to short circulation times and suboptimal biodistribution of the therapeutic enzymes.
André R. A. Marques (8636508) +17 more
core +1 more source
Objective: To evaluate the serum concentrations of the three markers of lysosomal hydrolases (cathepsin D, acid phosphatase (AP) and acid DNAse (aDNAase) in men with coronary heart disease (CHD), depending on the levels of testosterone (T), estradiol (E2)
O. V. Tsygankova +6 more
doaj
CIRCADIAN AND CIRCANNUAL RHYTHMS OF SEVERAL ENZYMES OF LYSOSOMAL ORIGIN IN HUMAN-PLASMA
The circadian and circannual group rhythms in the plasma concentrations of the following lysosomal enzymes were studied in women and men: β-d-N-acetylglucosaminidase, β-d-glucuronidase, β-d-glucosidase, β-d-galactosidase, α-d-galactosidase, α-l ...
G. TETTAMANTI +15 more
core +1 more source
Currently available enzyme replacement therapies for lysosomal storage diseases are limited in their effectiveness due in part to short circulation times and suboptimal biodistribution of the therapeutic enzymes.
André R. A. Marques (8636508) +17 more
core +1 more source
Intralysosomal pH and release of lysosomal enzymes in the rat liver after exhaustive exercise
The mechanism underlying exhaustive exercise-induced release of lysosomal enzymes was studied in the rat liver. Exhaustive exercise resulted in the release of beta-glucuronidase and cathepsin D, but not beta-glucosidase and acid phosphatase, into the ...
M. Tsuboi +5 more
core +1 more source
Lysosomal disruption during the development of endotoxic shock in the baboon [PDF]
The original version is available at http://www.samj.org.za/Lysosomal disruption with release of lysosomal enzymes has been described in shock. This study was designed to demonstrate the release of lysosomal enzymes in the liver and lung in addition to ...
Kuhn, S. H. +2 more
core
Production of lysosomal enzymes in plant-based expression systems
The invention relates to the production of enzymatically active recombinant human and animal lysosomal enzymes involving construction and expression of recombinant expression constructs comprising coding sequences of human or animal lysosomal enzymes in ...
core
The activities of four lysosomal enzymes, i.e. N-acetyl-beta-hexosaminidase, acid phosphatase, alpha-D-mannosidase and alpha-L-fucosidase have been measured in extracts of endometrial biopsies from untreated and levonorgestrel-treated women of fertile ...
Cornillie, F. +5 more
core +1 more source
Krabbe disease is a devastating neurodegenerative lysosomal storage disorder caused by a deficiency of β-galactocerebrosidase (GALC). Gene therapy is a promising therapeutic approach for Krabbe disease.
Xing-Li Meng +3 more
doaj +1 more source

