Results 11 to 20 of about 82,606 (197)
European Journal of Entomology, 2022 In this study, haemocytes present in Papilio hyperbius Linnaeus were identified and characterized. Six different types of haemocyte were recorded in the haemocoel of this species of insect: prohaemocytes, plasmatocytes, granulocytes, spherulocytes ...
Min-Soo GO +6 more
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Biomedicines, 2022 Despite the numerous advances in tumor molecular biology and chemotherapy options, gastric adenocarcinoma is still the most frequent form of gastric cancer. One of the core proteins that regulates inter-cellular adhesion, E-cadherin plays important roles
Ilona Mihaela Liliac +7 more
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IUBMB Life (International Union of Biochemistry and Molecular Biology: Life), 2006 The lysosomal compartment is the place for cellular degradation of endocytosed and autophagocytosed material and a center for normal turnover of organelles as well as most long-lived proteins. Lysosomes were long considered stable structures that broke and released their many hydrolytic enzymes only following necrotic cell death.
A, Terman +3 more
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β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway
Cell, 2020 β-Coronaviruses are a family of positive-strand enveloped RNA viruses that includes the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Much is known regarding their cellular entry and replication pathways, but their mode of egress remains ...
Sourish Ghosh +17 more
semanticscholar +1 more source
Targeting lysosomes in human disease: from basic research to clinical applications
Signal Transduction and Targeted Therapy, 2021 In recent years, accumulating evidence has elucidated the role of lysosomes in dynamically regulating cellular and organismal homeostasis. Lysosomal changes and dysfunction have been correlated with the development of numerous diseases.
Mengdie Cao +3 more
semanticscholar +1 more source
Functions of lysosomes in mammalian female reproductive system
Reproductive and Developmental Medicine, 2020 The lysosome is the most acidic membrane-bound intracellular organelle. Lysosomal acidity is primarily maintained by vacuolar H+-ATPase (V-ATPase) and counter ion channels.
Yuehuan Li +3 more
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Cogs in the autophagic machine—equipped to combat dementia-prone neurodegenerative diseases
Frontiers in Molecular Neuroscience, 2023 Neurodegenerative diseases are often characterized by hydrophobic inclusion bodies, and it may be the case that the aggregate-prone proteins that comprise these inclusion bodies are in fact the cause of neurotoxicity.
Sholto de Wet, Rensu Theart, Ben Loos
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Akt Is S-Palmitoylated: A New Layer of Regulation for Akt
Frontiers in Cell and Developmental Biology, 2021 The protein kinase Akt/PKB participates in a great variety of processes, including translation, cell proliferation and survival, as well as malignant transformation and viral infection.
Matías Blaustein +23 more
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Tissue-specific targeting of DNA nanodevices in a multicellular living organism
eLife, 2021 Nucleic acid nanodevices present great potential as agents for logic-based therapeutic intervention as well as in basic biology. Often, however, the disease targets that need corrective action are localized in specific organs, and thus realizing the full
Kasturi Chakraborty +9 more
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TRPML1—Emerging Roles in Cancer
Cells, 2020 The mucolipin-1 (TRPML1) channel maintains lysosomal ionic homeostasis and regulates autophagic flux. Defects of TRPML1 lead to lysosomal storage diseases and neurodegeneration.
Yiming Yang +2 more
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