The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis
Journal of Periodontal Research, EarlyView.Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis +2 more
wiley +1 more source
Investigating the Effect of Isoelectric Points on the Gas-Phase Stability of Native-like Proteins Analyzed in Positive- versus Negative-Ion Mode by IMS-MS. [PDF]
Anal ChemEdwards AN +3 more
europepmc +1 more source
The Hemoprotein Hhy1 Promotes Heme‐Dependent Catalase Activity of Ctt1
Molecular Microbiology, EarlyView.A Schizosaccharomyces pombe strain deficient in heme (hem1Δ) and siderophore (Fc) biosynthesis, as well as high‐affinity iron (Fe) uptake (blue), was used to uncover the hemoprotein Hhy1 that promotes the heme‐dependent activity of the catalase Ctt1. In contrast, hhy1Δ cells exhibit reduced Ctt1 activity and increased sensitivity to oxidative stress ...
Tobias Vahsen +3 more
wiley +1 more source
Role of the Surface in Conformational Changes in Lysozymes: Effect of a Gold Surface and a Lipid Membrane. [PDF]
Int J Mol SciKaminska A +3 more
europepmc +1 more source
Metacaspases contribute to the cellular response to heat stress in a marine diatom
New Phytologist, EarlyView.Summary Climate‐driven marine heatwaves (HW) are extreme, large‐scale events characterized by elevated ocean temperatures lasting from days to months. Despite their importance, little is known about the molecular mechanisms of algal response to marine HW. Recent studies suggest that metacaspases play an important role in thermotolerance.
Mai Sadeh +6 more
wiley +1 more source
Development of the HTRF assay to evaluate the auxin‐induced binding between TIR1 and IAA7
New Phytologist, EarlyView.Summary Auxin plays diverse roles in plant growth and development, including sensing environmental changes. Quantifying the interaction between auxin coreceptors provides the molecular basis for cells to sense and adapt to environmental cues. Although several assays are available, a more high‐throughput method is necessary to efficiently evaluate the ...
Jekson Robertlee, Shinya Hagihara
wiley +1 more source
Physicochemical Properties Determination of Recombinant Human Lysozyme and Its Effects on Intestinal Development in Mice. [PDF]
NutrientsLiu R +7 more
europepmc +1 more source
Salivary Proteomic Signatures in Pregnant Women With Excessive Gingival Bleeding
Oral Diseases, EarlyView.ABSTRACT Objective This observational, cross‐sectional, and analytical study aimed to explore the pathophysiological mechanisms of gingivitis in pregnancy by analyzing the salivary proteomic profile according to gingival bleeding status. Materials and Methods Pregnant women at the 27th week of gestation or beyond were categorized into two groups: those
Gerson Aparecido Foratori‐Junior +9 more
wiley +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Sheath blight disease of rice caused by the fungal pathogen R. solani AG1‐IA remains a big threat to rice production worldwide. A limited genetic variation in rice for tolerance to this pathogen and little success in understanding how it defeats host defence are major reasons behind it.
Vinod Kumar +5 more
wiley +1 more source