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Phage lytic enzymes are enzymes produced by bacterial viruses, either as part of their virion to facilitate bacterial infection through local peptidoglycan degradation, or as soluble proteins to induce massive cell lysis at the end of the lytic ...
Yves Briers
doaj +6 more sources
Nanoparticles Influence Lytic Phage T4-like Performance In Vitro. [PDF]
Little is known about interactions of non-filamentous, complex-structured lytic phages and free, non-ordered nanoparticles. Emerging questions about their possible bio-sanitization co-applications or predictions of possible contact effects in the environment require testing. Therefore, we revealed the influence of various nanoparticles (NPs; SiO2, TiO2-
Stachurska X +5 more
europepmc +3 more sources
The characteristic and potential therapeutic effect of isolated multidrug-resistant Acinetobacter baumannii lytic phage [PDF]
Background Widespread misuse of antibiotics caused bacterial resistance increasingly become a serious threat. Bacteriophage therapy promises alternative treatment strategies for combatting drug-resistant bacterial infections.
Behnam Sisakhtpour +5 more
doaj +2 more sources
PhaLP: A Database for the Study of Phage Lytic Proteins and Their Evolution
Phage lytic proteins are a clinically advanced class of novel enzyme-based antibiotics, so-called enzybiotics. A growing community of researchers develops phage lytic proteins with the perspective of their use as enzybiotics.
Bjorn Criel +4 more
doaj +1 more source
Background: Global emergence of carbapenem-resistant Klebsiella pneumoniae is a major public health concern. Phage therapy – application of lytic phage to kill pathogenic bacteria – is considered as one of the promising alternatives to tackle this ...
Gunaraj Dhungana +9 more
doaj +1 more source
The tripartite associations between bacteriophage, Wolbachia, and arthropods. [PDF]
By manipulating arthropod reproduction worldwide, the heritable endosymbiont Wolbachia has spread to pandemic levels. Little is known about the microbial basis of cytoplasmic incompatibility (CI) except that bacterial densities and percentages of ...
Seth R Bordenstein +4 more
doaj +2 more sources
Isolation and Identification of Escherichia coli O157:H7 Lytic Bacteriophage from Environment Sewage
Escherichia coli O157:H7 is one of the pathogenic bacteria causing foodborne disease. The use of lytic bacteriophages can be a good solution to overcome the disease.
Tessa Sjahriani +2 more
doaj +1 more source
Characterization of newly isolated lytic bacteriophages active against Acinetobacter baumannii [PDF]
Based on genotyping and host range, two newly isolated lytic bacteriophages, myovirus vB_AbaM_Acibel004 and podovirus vB_AbaP_Acibel007, active against Acinetobacter baumannii clinical strains, were selected from a new phage library for further ...
De Vos, Daniel +9 more
core +7 more sources
pH-Dependent Lytic Peptides Discovered by Phage Display [PDF]
Lipid membranes compartmentalize eukaryotic cells and separate the cell interior from the extracellular milieu. So far, studies of peptide and protein interactions with membranes have largely been limited to naturally occurring peptides or to sequences designed on the basis of structural information and biophysical parameters.
Sachiko, Hirosue, Thomas, Weber
openaire +2 more sources
Phage lytic proteins: biotechnological applications beyond clinical antimicrobials [PDF]
Most bacteriophages encode two types of cell wall lytic proteins: endolysins (lysins) and virion-associated peptidoglycan hydrolases. Both enzymes have the ability to degrade the peptidoglycan of Gram-positive bacteria resulting in cell lysis when they are applied externally. Bacteriophage lytic proteins have a demonstrated potential in treating animal
Rodríguez, Lorena +5 more
openaire +3 more sources

