Results 31 to 40 of about 30,001 (226)

Mutation-induced infections of phage-plasmids

open access: yesNature Communications, 2023
Phage-plasmids are extra-chromosomal elements that act both as plasmids and as phages, whose eco-evolutionary dynamics remain poorly constrained. Here, we show that segregational drift and loss-of-function mutations play key roles in the infection ...
Xiaoyu Shan   +2 more
doaj   +1 more source

Role of temperate phage in determining lytic phage sensitivity and serotype of Vibrio cholerae [PDF]

open access: yesInfection and Immunity, 1982
The effect of lysogenization with five temperate phages from various sources on serotype and lytic phage sensitivity was investigated in six cultures of Vibrio cholerae of both classical and El Tor biotypes. No changes in serotype or in classical phage sensitivity in the classical biotype were observed.
K A, Siddiqui, F K, Bhattacharyya
openaire   +2 more sources

Quorum Sensing and Metabolic State of the Host Control Lysogeny-Lysis Switch of Bacteriophage T1

open access: yesmBio, 2019
Bacterial viruses, or bacteriophages, are highly abundant in the biosphere and have a major impact on microbial populations. Many examples of phage interactions with their hosts, including establishment of dormant lysogenic and active lytic states, have ...
Leanid Laganenka   +5 more
doaj   +1 more source

Strategy for mass production of lytic Staphylococcus aureus bacteriophage pSa-3: contribution of multiplicity of infection and response surface methodology

open access: yesMicrobial Cell Factories, 2021
Background Antibiotic-resistant bacteria have emerged as a serious problem; bacteriophages have, therefore, been proposed as a therapeutic alternative to antibiotics.
Sang Guen Kim   +9 more
doaj   +1 more source

Comparative genomics of Shiga toxin encoding bacteriophages [PDF]

open access: yes, 2012
Background Stx bacteriophages are responsible for driving the dissemination of Stx toxin genes (stx) across their bacterial host range. Lysogens carrying Stx phages can cause severe, lifethreatening disease and Stx toxin is an integral virulence factor.
Alan J McCarthy   +20 more
core   +1 more source

PHAGE COCKTAILS AGAINST HIGHLY MULTI-DRUG RESISTANT ACINETOBACTER BAUMANII

open access: yesThe Iraqi Journal of Medical Sciences, 2018
Background:Phage therapy is a potential alternative treatment for infections caused by many bacterial species such as Acinetobacter baumannii (A.
Hayder Jasim, Ahmad Abdul-Ameer
doaj   +1 more source

Characterization of Three Phages Lytic for Brucella Species

open access: yesJournal of General Virology, 1973
Summary The brucella phages A422, M51 and S708 were examined and compared with the Tbilisi reference phage. A422 was found to be identical in host range, adsorption pattern, physical and chemical stability and serological specificity with Tbilisi phage.
J A, Morris, M J, Corbel, J I, Phillip
openaire   +2 more sources

Construction of Leaderless-Bacteriocin-Producing Bacteriophage Targeting E. coli and Neighboring Gram-Positive Pathogens

open access: yesMicrobiology Spectrum, 2021
Lytic bacteriophages are expected as effective tools to control infectious bacteria in human and pathogenic or spoilage bacteria in foods. Leaderless bacteriocins (LLBs) are simple bacteriocins produced by Gram-positive bacteria. LLBs do not possess an N-
Yoshimitsu Masuda   +4 more
doaj   +1 more source

Properties of a new phage lytic for Brucella Suis

open access: yesJournal of General Virology, 1973
Summary The properties of a new brucella phage isolated from culture fluids of Brucella suis and designated the Weybridge phage, were examined. The phage was lytic for smooth Br. abortus, Br. suis and Br. neotomae cultures but there was no lysis of Br. melitensis, Br. canis or Br. ovis strains. The host range, adsorption pattern, chemical stability and
J A, Morris, M J, Corbel
openaire   +2 more sources

Peptidoglycan lytic activity of thePseudomonas aeruginosaphage φKZ gp144 lytic transglycosylase [PDF]

open access: yesFEMS Microbiology Letters, 2007
The gp144 endolysin gene from the Pseudomonas aeruginosa phage phiKZ was cloned and studies of gp144 expression into Escherichia coli showed host cell lysis. The gp144 protein was purified directly from the culture supernatant and from the bacterial cell pellet and showed in vitro antibacterial lytic activity against P. aeruginosa bacteria and degraded
Catherine, Paradis-Bleau   +7 more
openaire   +2 more sources

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