Results 51 to 60 of about 108,965 (216)
Biofilm spatial structure and superinfection immunity modulate inter-phage competition.
PLoS BiologyObligately lytic (virulent) phages always lyse host cells to release progeny viruses, while temperate phages can either lyse their hosts or integrate into host genomes as prophages, forming lysogens.
James B Winans, Carey D Nadell
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Viruses, 2022 Validated methods for phage selection, host range expansion, and lytic activity determination are indispensable for maximizing phage therapy outcomes. In this review, we describe some relevant methods, highlighting their advantages and disadvantages, and
Tea Glonti, Jean-Paul Pirnay
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Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Advanced Science, EarlyView.Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
Exploring phage mechanisms that enhance activity [PDF]
, 2017 In recent years, there has been a renewed interest in using bacteriophages as an alternate agent for the treatment of multi-drug resistant bacteria. One such highly drug-resistant group of bacteria is the Burkholderia cepacia complex (Bcc), which causes ...
Kamal, Fatima
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Advanced Science, EarlyView.This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun +7 more
wiley +1 more source
Frontiers in Microbiology, 2017 The rumen is known to harbor dense populations of bacteriophages (phages) predicted to be capable of infecting a diverse range of rumen bacteria. While bacterial genome sequencing projects are revealing the presence of phages which can integrate their ...
Rosalind A. Gilbert +11 more
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Complexities associated with expression of Epstein-Barr virus (EBV) lytic origins of DNA replication. [PDF]
, 2007 EBV has two lytic origins (oriLyt) of DNA replication lying at divergent sites on the viral genome within a duplicated sequence (DS). The latter contains potential hairpin loops, ‘hinge’ elements and the promoters for transcripts from viral genes BHLF1 ...
Xue, SA, Griffin, BE
core
Structural and Biochemical Characterization of a New Phage-Encoded Muramidase, KTN6 Gp46 [PDF]
Endolysins are phage-encoded lytic enzymes that degrade bacterial peptidoglycan at the end of phage lytic cycles to release new phage particles.
van Ryne, Michael +23 more
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Isolation and characterization of a T7-like lytic phage for Pseudomonas fluorescens [PDF]
BMC Biotechnology, 2008 AbstractBackgroundDespite the proven relevance ofPseudomonas fluorescensas a spoilage microorganism in milk, fresh meats and refrigerated food products and the recognized potential of bacteriophages as sanitation agents, so far no phages specific forP.
Sillankorva, Sanna +2 more
openaire +3 more sources
Frontiers in Veterinary Science, 2021 Inappropriate use of antibiotics has accelerated to the emergence of multidrug-resistant bacteria, becoming a major health threat. Moreover, bacterial biofilms contribute to antibiotic resistance and prolonged infections.
Chenglin Tao +15 more
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