Results 31 to 40 of about 44,822 (222)

Efficacy of lytic Staphylococcus aureus bacteriophage against multidrug-resistant Staphylococcus aureus in mice

open access: yesJournal of Infection in Developing Countries, 2016
Introduction: The use of bacteriophages as an alternative treatment method against multidrug-resistant bacteria has not been explored in Kenya. This study sought to determine the efficacy of environmentally obtained lytic bacteriophage against multidrug ...
Joseph Michael Ochieng' Oduor   +4 more
doaj   +1 more source

Strategy for mass production of lytic Staphylococcus aureus bacteriophage pSa-3: contribution of multiplicity of infection and response surface methodology

open access: yesMicrobial Cell Factories, 2021
Background Antibiotic-resistant bacteria have emerged as a serious problem; bacteriophages have, therefore, been proposed as a therapeutic alternative to antibiotics.
Sang Guen Kim   +9 more
doaj   +1 more source

Molecular bases and role of viruses in the human microbiome. [PDF]

open access: yes, 2014
Viruses are dependent biological entities that interact with the genetic material of most cells on the planet, including the trillions within the human microbiome.
Abeles, Shira R, Pride, David T
core   +1 more source

Quorum Sensing and Metabolic State of the Host Control Lysogeny-Lysis Switch of Bacteriophage T1

open access: yesmBio, 2019
Bacterial viruses, or bacteriophages, are highly abundant in the biosphere and have a major impact on microbial populations. Many examples of phage interactions with their hosts, including establishment of dormant lysogenic and active lytic states, have ...
Leanid Laganenka   +5 more
doaj   +1 more source

Integrative omics analysis of Pseudomonas aeruginosa virus PA5oct highlights the molecular complexity of jumbo phages [PDF]

open access: yes, 2020
Pseudomonas virus vB_PaeM_PA5oct is proposed as a model jumbo bacteriophage to investigate phage-bacteria interactions and is a candidate for phage therapy applications.
Blasdel, Bob G.   +9 more
core   +1 more source

PHAGE COCKTAILS AGAINST HIGHLY MULTI-DRUG RESISTANT ACINETOBACTER BAUMANII

open access: yesThe Iraqi Journal of Medical Sciences, 2018
Background:Phage therapy is a potential alternative treatment for infections caused by many bacterial species such as Acinetobacter baumannii (A.
Hayder Jasim, Ahmad Abdul-Ameer
doaj   +1 more source

Comparative genomics of Shiga toxin encoding bacteriophages [PDF]

open access: yes, 2012
Background Stx bacteriophages are responsible for driving the dissemination of Stx toxin genes (stx) across their bacterial host range. Lysogens carrying Stx phages can cause severe, lifethreatening disease and Stx toxin is an integral virulence factor.
Allison, Heather   +6 more
core   +2 more sources

Construction of Leaderless-Bacteriocin-Producing Bacteriophage Targeting E. coli and Neighboring Gram-Positive Pathogens

open access: yesMicrobiology Spectrum, 2021
Lytic bacteriophages are expected as effective tools to control infectious bacteria in human and pathogenic or spoilage bacteria in foods. Leaderless bacteriocins (LLBs) are simple bacteriocins produced by Gram-positive bacteria. LLBs do not possess an N-
Yoshimitsu Masuda   +4 more
doaj   +1 more source

In Vitro Techniques and Measurements of Phage Characteristics That Are Important for Phage Therapy Success

open access: yesViruses, 2022
Validated methods for phage selection, host range expansion, and lytic activity determination are indispensable for maximizing phage therapy outcomes. In this review, we describe some relevant methods, highlighting their advantages and disadvantages, and
Tea Glonti, Jean-Paul Pirnay
doaj   +1 more source

A bacteriophage tubulin harnesses dynamic instability to center DNA in infected cells. [PDF]

open access: yes, 2014
Dynamic instability, polarity, and spatiotemporal organization are hallmarks of the microtubule cytoskeleton that allow formation of complex structures such as the eukaryotic spindle. No similar structure has been identified in prokaryotes.
Agard, David A   +6 more
core   +2 more sources

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