Results 91 to 100 of about 4,488 (200)
Bacteriophage endolysins as a response to emerging foodborne pathogens [PDF]
Continuous reports on foodborne outbreaks and increasing prevalence of antibiotic-resistant bacteria call for the development of novel preservation techniques that assure the safety of food products.
Azeredo, Joana+3 more
core +1 more source
ABSTRACT The evolving threat of new pathogen variants in the face of global environmental changes poses a risk to a sustainable crop production. Predicting and responding to how climate change affects plant‐pathosystems is challenging, as environment affects host–pathogen interactions from molecular to the community level, and with eco‐evolutionary ...
Amanpreet Kaur+5 more
wiley +1 more source
Shigellosis remains a worldwide health problem due to the lack of vaccines and the emergence of antibiotic-resistant strains. Shigella (S.) dysenteriae has rigid peptidoglycan (PG), and its tight regulation of biosynthesis and remodeling is essential for bacterial integrity.
Baleegh A Kadhim+2 more
openaire +2 more sources
A proposed integrated approach for the preclinical evaluation of phage therapy in Pseudomonas infections [PDF]
Bacteriophage therapy is currently resurging as a potential complement/alternative to antibiotic treatment. However, preclinical evaluation lacks streamlined approaches.
Arabski, Michal+13 more
core +2 more sources
Modulation of the lytic apparatus by the FtsEX complex within the bacterial division machinery
Conformational changes involved in the mechano‐transmission activation of the lytic machinery by FtsEX. This model is based on the Gram‐negative bacterium Pseudomonas aeruginosa, highlighting the EnvC protein that facilitates the activation of the lytic enzyme AmiB during cell division.
Martín Alcorlo+5 more
wiley +1 more source
Pseudomonas aeruginosa encodes the beta-lactamase AmpC, which promotes resistance to beta-lactam antibiotics. Expression of ampC is induced by anhydro-muropeptides (AMPs) released from the peptidoglycan (PG) cell wall upon beta-lactam treatment. AmpC can
Joël Gyger+4 more
doaj +1 more source
Characterization of IsaA and SceD, Two Putative Lytic Transglycosylases of Staphylococcus aureus [PDF]
ABSTRACT Bacterial cell wall peptidoglycan is a dynamic structure requiring hydrolysis to allow cell wall growth and division. Staphylococcus aureus has many known and putative peptidoglycan hydrolases, including two likely lytic transglycosylases. These two proteins, IsaA and SceD, were both found to have
Melanie R. Stapleton+8 more
openalex +4 more sources
Cell wall peptidoglycan in Mycobacterium tuberculosis: An Achilles’ heel for the TB-causing pathogen [PDF]
Tuberculosis (TB), caused by the intracellular pathogen Mycobacterium tuberculosis, remains one of the leading causes of mortality across the world. There is an urgent requirement to build a robust arsenal of effective antimicrobials, targeting novel ...
Bhakta, S+6 more
core +2 more sources
Salmonella encodes two peptidoglycan synthases, PBP3 and PBP3SAL, which can promote cell division independently. This study shows by in vivo cross‐linking and proteomics that PBP3 and PBP3SAL do not interact in the division complex and that ~40 proteins may associate direct or indirectly to these enzymes, including expected divisome components and new ...
Sónia Castanheira+3 more
wiley +1 more source
Brucella abortus Encodes an Active Rhomboid Protease: Proteome Response after Rhomboid Gene Deletion
Rhomboids are intramembrane serine proteases highly conserved in the three domains of life. Their key roles in eukaryotes are well understood but their contribution to bacterial physiology is still poorly characterized.
María Inés Marchesini+3 more
doaj +1 more source