Results 71 to 80 of about 2,299 (155)

Purification and properties of a membrane-bound lytic transglycosylase from Escherichia coli [PDF]

open access: yesJournal of Bacteriology, 1994
A membrane-bound lytic transglycosylase (Mlt) has been solubilized in the presence of 2% Triton X-100 containing 0.5 M NaCl from membranes of an Escherichia coli mutant that carries a deletion in the slt gene coding for a 70-kDa soluble lytic transglycosylase (Slt70).
Ursinus, A. ; https://orcid.org/0009-0005-4319-2991   +1 more
openaire   +3 more sources

Structural Analysis of PlyKp104, a Novel Phage Endoysin

open access: yesCrystals
Antibiotic resistance has emerged as a critical global public health challenge, prompting increased interest in non-antibiotic antimicrobial strategies such as bacteriophage-derived endolysins.
Jung-Min Choi
doaj   +1 more source

Phage‐derived proteins: Advancing food safety through biocontrol and detection of foodborne pathogens

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 2, March 2025.
Abstract The emergence of antimicrobial‐resistant foodborne pathogens poses a continuous health risk and economic burden as they can easily spread through contaminated food. Therefore, the demand for new antimicrobial agents to address this problem is steadily increasing.
Dahee Choi, Sangryeol Ryu, Minsuk Kong
wiley   +1 more source

Structure of MltG from Mycobacterium abscessus reveals structural plasticity between composed domains

open access: yesIUCrJ
MltG, a membrane-bound lytic transglycosylase, has roles in terminating glycan polymerization in peptidoglycan and incorporating glycan chains into the cell wall, making it significant in bacterial cell-wall biosynthesis and remodeling.
Gwan Hee Lee   +7 more
doaj   +1 more source

Mycobacteriophage endolysins: diverse and modular enzymes with multiple catalytic activities. [PDF]

open access: yesPLoS ONE, 2012
The mycobacterial cell wall presents significant challenges to mycobacteriophages--viruses that infect mycobacterial hosts--because of its unusual structure containing a mycolic acid-rich mycobacterial outer membrane attached to an arabinogalactan layer ...
Kimberly M Payne, Graham F Hatfull
doaj   +1 more source

Navigating Host Immunity and Concurrent Ozone Stress: Strain‐Resolved Metagenomics Reveals Maintenance of Intraspecific Diversity and Genetic Variation in Xanthomonas on Pepper

open access: yesEvolutionary Applications, Volume 18, Issue 1, January 2025.
ABSTRACT The evolving threat of new pathogen variants in the face of global environmental changes poses a risk to a sustainable crop production. Predicting and responding to how climate change affects plant‐pathosystems is challenging, as environment affects host–pathogen interactions from molecular to the community level, and with eco‐evolutionary ...
Amanpreet Kaur   +5 more
wiley   +1 more source

Interaction and modulation of two antagonistic cell wall enzymes of mycobacteria. [PDF]

open access: yesPLoS Pathogens, 2010
Bacterial cell growth and division require coordinated cell wall hydrolysis and synthesis, allowing for the removal and expansion of cell wall material. Without proper coordination, unchecked hydrolysis can result in cell lysis.
Erik C Hett   +2 more
doaj   +1 more source

Modulation of the lytic apparatus by the FtsEX complex within the bacterial division machinery

open access: yesFEBS Letters, Volume 598, Issue 23, Page 2836-2851, December 2024.
Conformational changes involved in the mechano‐transmission activation of the lytic machinery by FtsEX. This model is based on the Gram‐negative bacterium Pseudomonas aeruginosa, highlighting the EnvC protein that facilitates the activation of the lytic enzyme AmiB during cell division.
Martín Alcorlo   +5 more
wiley   +1 more source

Reactions of All Escherichia coli Lytic Transglycosylases with Bacterial Cell Wall [PDF]

open access: yesJournal of the American Chemical Society, 2013
The reactions of all seven Escherichia coli lytic transglycosylases with purified bacterial sacculus are characterized in a quantitative manner. These reactions, which initiate recycling of the bacterial cell wall, exhibit significant redundancy in the activities of these enzymes along with some complementarity.
Lee, Mijoon   +6 more
openaire   +3 more sources

Breaking barriers: pCF10 type 4 secretion system relies on a self-regulating muramidase to modulate the cell wall

open access: yesmBio
Conjugative type 4 secretion systems (T4SSs) are the main driver for the spread of antibiotic resistance genes and virulence factors in bacteria.
Wei-Sheng Sun   +4 more
doaj   +1 more source

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