Metagenomic and functional analysis of hindgut microbiota of a wood-feeding higher termite [PDF]
From the standpoints of both basic research and biotechnology, there is considerable interest in reaching a clearer understanding of the diversity of biological mechanisms employed during lignocellulose degradation.
Leadbetter, Jared R.+2 more
core
Bacteriophage endolysins as a response to emerging foodborne pathogens [PDF]
Continuous reports on foodborne outbreaks and increasing prevalence of antibiotic-resistant bacteria call for the development of novel preservation techniques that assure the safety of food products.
Azeredo, Joana+3 more
core +1 more source
Modeling of the genetic switch of bacteriophage TP901-1: A heteromer of CI and MOR ensures robust bistability [PDF]
The lytic-lysogenic switch of the temperate lactococcal phage TP901-1 is fundamentally different from that of phage lambda. In phage TP901-1, the lytic promoter PL is repressed by CI whereas repression of the lysogenic promoter PR requires the presence of both of the antagonistic regulator proteins, MOR and CI.
arxiv
A proposed integrated approach for the preclinical evaluation of phage therapy in Pseudomonas infections [PDF]
Bacteriophage therapy is currently resurging as a potential complement/alternative to antibiotic treatment. However, preclinical evaluation lacks streamlined approaches.
Arabski, Michal+13 more
core +2 more sources
Temperate and chronic virus competition leads to low lysogen frequency [PDF]
The canonical bacteriophage is obligately lytic: the virus infects a bacterium and hijacks cell functions to produce large numbers of new viruses which burst from the cell. These viruses are well-studied, but there exist a wide range of coexisting virus lifestyles that are less understood.
arxiv
Characterization of Brucella abortus mutant strain Δ22915, a potential vaccine candidate
Brucellosis, caused by Brucella spp., is an important zoonosis worldwide. Vaccination is an effective strategy for protection against Brucella infection in livestock in developing countries and in wildlife in developed countries. However, current vaccine
Yanqing Bao+5 more
doaj +1 more source
An HMM-based behavior modeling approach for continuous mobile authentication [PDF]
This paper studies continuous authentication for touch interface based mobile devices. A Hidden Markov Model (HMM) based behavioral template training approach is presented, which does not require training data from other subjects other than the owner of the mobile. The stroke patterns of a user are modeled using a continuous left-right HMM.
arxiv +1 more source
The PECACE domain: a new family of enzymes with potential peptidoglycan cleavage activity in Gram-positive bacteria [PDF]
BACKGROUND: The metabolism of bacterial peptidoglycan is a dynamic process, synthases and cleavage enzymes are functionally coordinated. Lytic Transglycosylase enzymes (LT) are part of multienzyme complexes which regulate bacterial division and ...
Di Guilmi, Anne Marie+3 more
core +3 more sources
Cell wall peptidoglycan in Mycobacterium tuberculosis: An Achilles’ heel for the TB-causing pathogen [PDF]
Tuberculosis (TB), caused by the intracellular pathogen Mycobacterium tuberculosis, remains one of the leading causes of mortality across the world. There is an urgent requirement to build a robust arsenal of effective antimicrobials, targeting novel ...
Bhakta, S+6 more
core +2 more sources
Probabilistic and Flux Landscapes of the Phage $λ$ Genetic Switch [PDF]
The phage $\lambda$ infection of an \textit{E. coli} cell has become a paradigm for understanding the molecular processes involved in gene expression and cell signaling. This system provides an example of a genetic switch, as cells with identical DNA choose either of two cell cycles: a lysogenic cycle, in which the phage genome is incorporated into the
arxiv