Results 151 to 160 of about 4,722 (203)

Bacterial lytic transglycosylases: Biochemical characterization and rational design of inhibitors

open access: yes, 2005
Lytic transglycosylases cleave the [beta]-(1[right arrow]4) glycosidic bond in the bacterial cell wall heteropolymer, peptidoglycan, between the ' N'-acetylmuramic acid (MurNAc) and 'N'-acetylglucosamine (GlcNAc) residues with the concomitant formation of a 1,6 anhydromuramoyl residue.
openaire   +2 more sources

Identification of YfhD from Escherichia coli as membrane-bound lytic transglycosylase F, the archetype for family 1B lytic transglycosylases

open access: yes, 2008
This thesis is an investigation of the activity of the hypothetical protein product of the open reading frame from 'Escherichia coli' identified as 'yfhD'. We demonstrated that YfhD functions as a lytic transglycosylase (LT) and renamed it membrane-bound lytic transglycosylase F (MltF).
openaire   +1 more source

Phage-Derived Endolysins Against Resistant Staphylococcus spp.: A Review of Features, Antibacterial Activities, and Recent Applications

open access: yesInfectious Diseases and Therapy
Antimicrobial resistance is a significant global public health issue, and the dissemination of antibiotic resistance in Gram-positive bacterial pathogens has significantly increased morbidity, mortality rates, and healthcare costs.
Mina Golban   +3 more
doaj   +1 more source

Crystal structure of Escherichia coli lytic transglycosylase Slt35 reveals a lysozyme-like catalytic domain with an EF-hand [PDF]

open access: bronze, 1999
E.J. van Asselt   +5 more
openalex   +1 more source

Identification of type VI secretion system effector-immunity pairs using structural bioinformatics

open access: yesMolecular Systems Biology
The type VI secretion system (T6SS) is an important mediator of microbe–microbe and microbe–host interactions. Gram-negative bacteria use the T6SS to inject T6SS effectors (T6Es), which are usually proteins with toxic activity, into neighboring cells ...
Alexander M Geller   +4 more
doaj   +1 more source

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