Results 61 to 70 of about 26,727 (247)

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Pt‐TiO2 mesoporous nanosystem co‐delivering phlorezin enables synergistic sonodynamic‐chemoimmunotherapy for hepatocellular carcinoma via directly targeting DDX5 and metabolic reprogramming modulation

BMEMat, EarlyView.
Abstract Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer‐related mortality globally, continues to pose significant therapeutic challenges. Here, we developed an innovative nanosystem, Phl@PT, based on Pt‐TiO2 nanoparticles for the co‐delivery of Phlorezin, presenting a novel approach for HCC treatment through sonodynamic ...
Kairui Liu, Bo Zhang, Yue Wan, Zhiru Yang, Abdusami Abdurahman, Mengxin He, Shengtao Hu, Yi Zhang, Xiaoke Li, Jin Chang, Jun Kang, Liren Liu, Wanghua Liu, Shao Li   +13 more
wiley   +1 more source

Phospholipase A2 Receptor Antibody–Positive Pregnancy: A Case Report

, 2020
© 2020 Renal course and clinical outcomes in pregnant women with primary membranous nephropathy are not completely understood. In addition, the use of autoantibodies to M-type phospholipase A2 receptor (PLA2R) as a serologic marker throughout pregnancy ...
Steven Fishbane, Laurence H. Beck, Ilene Miller, Sachdeva, M., Beck, L. H., Vanesa Bijol, Bijol, V., Mala Sachdeva, Miller, I., Fishbane, S.   +9 more
core   +1 more source

Clinical features, course and prognosis of idiopathic membranous nephropathy depending on the presence of antibodies against M-type phospholipase A2 receptor

Nefrología (English Edition), 2015
In membranous nephropathy, the presence of antibodies against M-type phospholipase A2 receptor is considered highly specific for idiopathic forms. However, no specific association to a particular clinical profile has been found for such antibodies ...
Elías Jatem Escalante, Alfons Segarra Medrano, Clara Carnicer Cáceres, M. Adoración Martín-Gómez, María Teresa Salcedo Allende, Helena Ostos Roldan, Irene Agraz Pamplona   +6 more
doaj   +1 more source

Prevalence of enhanced granular expression of thrombospondin type-1 domain-containing 7A (THSD7A) and M-type phospholipase A2 receptor (PLA2R) in the glomeruli of patients with idiopathic membranous nephropathy (MN) and secondary MN.

, 2015
Prevalence of enhanced granular expression of thrombospondin type-1 domain-containing 7A (THSD7A) and M-type phospholipase A2 receptor (PLA2R) in the glomeruli of patients with idiopathic membranous nephropathy (MN) and secondary MN.
Hideo Yasuda (710367), Satoshi Baba (540358), Naro Ohashi (168272), Akihiko Kato (798462), Takamasa Iwakura (798461)   +4 more
core   +1 more source

Characteristics of idiopathic membranous nephropathy (MN) patients with enhanced granular expression of thrombospondin type-1 domain-containing 7A (THSD7A) or M-type phospholipase A2 receptor (PLA2R) in the glomeruli.

, 2015
Characteristics of idiopathic membranous nephropathy (MN) patients with enhanced granular expression of thrombospondin type-1 domain-containing 7A (THSD7A) or M-type phospholipase A2 receptor (PLA2R) in the glomeruli.
Hideo Yasuda (710367), Satoshi Baba (540358), Naro Ohashi (168272), Akihiko Kato (798462), Takamasa Iwakura (798461)   +4 more
core   +1 more source

Designing Clinical Trials for the Treatment of Membranous Nephropathy in the Anti-Phospholipase A2 Receptor 1 Era: Results of a NephCure Membranous Nephropathy Workshop

Glomerular Diseases
Primary membranous nephropathy is a common cause of adult-onset nephrotic syndrome, with an overall incidence of 12 cases per million per year.
Marco Prunotto, Patrick H. Nachman, Barbara S. Gillespie, Laurence H. Beck, Aliza M. Thompson, Austin H. Hu, Elizabeth A. Stafford, Josh M. Tarnoff, Brad H. Rovin   +8 more
doaj   +1 more source

Experiencing 50 Years of Synergistic Development in Structural Biology and Enzymology

Journal of the Chinese Chemical Society, EarlyView.
Picture of Sunney Chan with Academia Sinica (AS) President James C. Liao and three Vice Presidents: Shin‐Kun Peng (left one), Tang K. Tang (right one), and Mei‐Yin Chou (right 2), taken at the annual Chinese New Year's Banquet of AS, February 7, 2025. This was likely Sunney's last appearance in formal activities of AS.
Ming‐Daw Tsai
wiley   +1 more source

The genetic and functional basis of three inherited cutaneous and gastrointestinal diseases in humans [PDF]

, 2014
This thesis describes investigations into the genetic basis and pathophysiology of three distinct inherited diseases in humans, two of which are strongly associated to the function of the ectodomain sheddase enzyme ADAM17.
Brooke, Matthew A
core  

Idiopathic Membranous Nephropathy: Glomerular Pathological Pattern Caused by Extrarenal Immunity Activity

Frontiers in Immunology, 2020
Idiopathic membranous nephropathy (IMN) is a pathological pattern of glomerular damage caused by an autoimmune response. Immune complex deposition, thickness of glomerular basement membrane, and changes in the podocyte morphology are responsible for the ...
Wenbin Liu, Chang Gao, Zhiyuan Liu, Haoran Dai, Zhendong Feng, Zhaocheng Dong, Yang Zheng, Yu Gao, Xuefei Tian, Baoli Liu   +9 more
doaj   +1 more source