Results 1 to 10 of about 28,514 (224)
Interaction of Human Lymphocyte Scavenger Receptors CD5 and CD6 with Toxins from Naja haje, Androctonus australis and Apis mellifera Venoms [PDF]
BiomoleculesAnimal venoms induce systemic inflammatory response syndrome through their interaction, inter alia, with pattern recognition receptors (PRRs) of the innate immune system.
Dalila Khemili +9 more
doaj +2 more sources
Effects of Mlx-8, a phospholipase A2 from Brazilian coralsnake Micrurus lemniscatus venom, on muscarinic acetylcholine receptors in rat hippocampus [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2020 Background: Here, we described the presence of a neurotoxin with phospholipase A2 activity isolated from Micrurus lemniscatus venom (Mlx-8) with affinity for muscarinic acetylcholine receptors (mAChRs).
Roberta Tancredi Francesco dos Santos +7 more
doaj +1 more source
Phospholipase A2 Receptor Antibodies in Membranous Nephropathy [PDF]
Journal of the American Society of Nephrology, 2014 The discovery of the M-type phospholipase A2 receptor (PLA2R) as a major antigen in idiopathic membranous nephropathy (iMN) was a breakthrough and established iMN as an autoimmune disease.1 Subsequent studies confirmed that antibodies against PLA2R were present in approximately 70% of incident iMN patients (reviewed by Hofstra and Wetzels2).
Hofstra, J.M., Wetzels, J.F.
openaire +2 more sources
Phospholipase A2 receptor and sarcoidosis-associated membranous nephropathy [PDF]
Nephrology Dialysis Transplantation, 2015 Of the glomerulonephritis associated with sarcoidosis, membranous nephropathy (MN) is the most prevalent. Coincidence or a causal relationship between these two diseases is unclear. Here, we present for the first time a high prevalence of PLA2R-related MN among patients with MN associated with active sarcoidosis.
T. Stehle +3 more
openaire +2 more sources
Current research status of PLA2R and malignancy associated membranous nephropathy
Linchuang shenzangbing zazhi, 2021 As a common cause of nephropathy syndrome in adults, membranous nephropathy（MN）often leads to end-stage renal disease.PLA2R related testing may aid a definite diagnosis of idiopathic MN.In recent years, we have detected some patients of malignancy ...
Zhu Wan-ting, Wang Yan-qiu
doaj
Anti-Phospholipase A2 Receptor Antibody in Membranous Nephropathy [PDF]
Journal of the American Society of Nephrology, 2011 The M-type phospholipase A2 receptor (PLA2R) is a target autoantigen in adult idiopathic membranous nephropathy (MN), but the prevalence of autoantibodies against PLA2R is unknown among Chinese patients with MN. Here, we measured anti-PLA2R antibody in the serum of 60 patients with idiopathic MN, 20 with lupus-associated MN, 16 with hepatitis B (HBV ...
Weisong, Qin +7 more
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Kidney Research and Clinical Practice, 2018 Background: Phospholipase A2 receptor (PLA2R) has been identified as a major autoantigen in primary membranous nephropathy (MN). We evaluated the association between anti-PLA2R antibodies and clinical outcome in Korean patients with primary MN.
Eun Joo Song +9 more
doaj +1 more source
BMC Nephrology, 2018 Background Serum anti-phospholipase A2 receptor (PLA2R) antibody was correlated with disease activity of membranous nephropathy(MN). The predictive value of antibody titer changes on immunosuppressive response remains unknown.
Chao Li +4 more
doaj +1 more source
iScience, 2023 Summary: Soluble epoxide hydrolase is a widely distributed bifunctional enzyme that contains N-terminal phosphatase (N-phos) and C-terminal epoxide hydrolase (C-EH) domains.
Feng Liu +5 more
doaj +1 more source
Toxins, 2020 Bee venom phospholipase A2 is a lipolytic enzyme in bee venom that catalyzes hydrolysis of the sn-2 ester bond of membrane phospholipids to produce free fatty acid and lysophospholipids.
Hyunjung Baek +6 more
doaj +1 more source