Results 201 to 210 of about 27,333,880 (308)

M tuberculosis and HIV infection

Biomedicine & Pharmacotherapy, 1993
openaire   +1 more source

Distribution and transmission of M. tuberculosis in a high-HIV prevalence city in Malawi: A genomic and spatial analysis. [PDF]

PLOS Glob Public Health
Chitwood MH, Corbett EL, Ndhlovu V, Sobkowiak B, Colijn C, Andrews JR, Burke RM, Cudahy PGT, Dodd PJ, Imai-Eaton JW, Engelthaler DM, Folkerts M, Feasey HRA, Lan Y, Lewis J, McNichol J, Menzies NA, Chipungu G, Nliwasa M, Weinberger DM, Warren JL, Salomon JA, MacPherson P, Cohen T.   +23 more
europepmc   +1 more source

LncRNA NORAD Enhances Inflammatory Injury in Sepsis‐Associated Acute Lung Damage Through miR‐150‐5p/STAT1‐Dependent NF‐κB Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Acute lung injury (ALI) is a severe complication of sepsis, yet the role of lncRNA NORAD in its pathogenesis remains unclear. Using LPS‐stimulated BEAS‐2B and HBEC3‐KT cells as well as cecal ligation and puncture (CLP)‐induced ALI models in C57BL/6 mice, we found that NORAD expression was markedly upregulated and promoted cell injury ...
Han Liu, Xi‐Xi Chen, Gui‐Hua Wei, Feng Li, Hai‐Yan Zong   +4 more
wiley   +1 more source

M & B 693 in Pneumonia complicating Tuberculosis [PDF]

BMJ, 1939
openaire   +2 more sources

Uncovering Key Characteristics of Antibacterial Peptides through Machine Learning

Macromolecular Rapid Communications, EarlyView.
Machine‐learning (ML) techniques using random forest classification models revealed key characteristics that predict effective antimicrobial peptides (AMPs) targeting Gram‐negative bacteria, Gram‐positive bacteria, and mycobacteria. The ideal cLogP (<$ < $−6) and net‐charge (≤+4) threshold was the same for all three targets with variations in the ...
Jooyoung Roh, Cyrille Boyer, Priyank V. Kumar   +2 more
wiley   +1 more source

Rapidly and reproducibly building a comprehensive catalogue of resistance-associated variants for M. tuberculosis

Adlard D, Malone KM, Westhead J, Hunt M, Thai H, Colpus M, Turner RD, Omar SV, Eyre DW, Ismail N, Walker TM, Peto TE, Crook DW, Iqbal Z, Fowler PW.   +14 more
europepmc   +1 more source

Trehalose dimycolate inhibits phagosome maturation and promotes intracellular <i>M. tuberculosis</i> growth via noncanonical SNARE interactions. [PDF]

Proc Natl Acad Sci U S A
Santamaria C, Biegas KJ, Lim PN, Cabral J, Kim CY, Lee JR, Gaidhane IV, Papson C, Gomard-Henshaw K, Rothchild AC, Swarts BM, Siegrist MS.   +11 more
europepmc   +1 more source

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui, Elena N. Kitova, Ling Han, Lara K. Mahal, John S. Klassen   +4 more
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Radiotherapy and Immune System Interactions Historical Perspectives and Clinical Advancements

Molecular Carcinogenesis, EarlyView.
ABSTRACT Radiotherapy (RT) has evolved significantly since its inception from treating benign conditions to becoming a cornerstone of cancer treatment. This review examines the complex interactions between RT and the immune system, highlighting its diverse effects on various immune cell populations, and exploring emerging strategies to enhance ...
Safiy Yahia, Ayman J. Oweida, Houda Bahig, Daniel Taussky   +3 more
wiley   +1 more source