Results 11 to 20 of about 1,738,596 (334)

M1/M2 macrophages and their overlaps – myth or reality?

open access: yesClinical science, 2023
Macrophages represent heterogeneous cell population with important roles in defence mechanisms and in homoeostasis. Tissue macrophages from diverse anatomical locations adopt distinct activation states.
Z. Strizova   +6 more
semanticscholar   +1 more source

Microglia Polarization From M1 to M2 in Neurodegenerative Diseases

open access: yesFrontiers in Aging Neuroscience, 2022
Microglia-mediated neuroinflammation is a common feature of neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS).
Shenrui Guo, Hui Wang, Yafu Yin
semanticscholar   +1 more source

The Role of M1/M2 Macrophage Polarization in Rheumatoid Arthritis Synovitis

open access: yesFrontiers in Immunology, 2022
Innate and adaptive immunity represent a harmonic counterbalanced system involved in the induction, progression, and possibly resolution of the inflammatory reaction that characterize autoimmune rheumatic diseases (ARDs), including rheumatoid arthritis ...
M. Cutolo   +3 more
semanticscholar   +1 more source

New insights into M1/M2 macrophages: key modulators in cancer progression

open access: yesCancer Cell International, 2021
Infiltration of macrophages in and around tumor nest represents one of the most crucial hallmarks during tumor progression. The mutual interactions with tumor cells and stromal microenvironment contribute to phenotypically polarization of tumor ...
Jiuyang Liu   +3 more
semanticscholar   +1 more source

Exosomal miR-30d-5p of neutrophils induces M1 macrophage polarization and primes macrophage pyroptosis in sepsis-related acute lung injury

open access: yesCritical Care, 2021
Polymorphonuclear neutrophils (PMNs) play an important role in sepsis-related acute lung injury (ALI). Accumulating evidence suggests PMN-derived exosomes as a new subcellular entity acting as a fundamental link between PMN-driven inflammation and tissue
Yang Jiao   +8 more
semanticscholar   +1 more source

Dental pulp stem cell-derived exosomes suppress M1 macrophage polarization through the ROS-MAPK-NFκB P65 signaling pathway after spinal cord injury

open access: yesJournal of Nanobiotechnology, 2022
Stem cell-derived exosomes have recently been regarded as potential drugs for treating spinal cord injury (SCI) by reducing reactive oxygen species (ROS) and suppressing M1 macrophage polarization. However, the roles of ROS and exosomes in the process of
Chao Liu   +11 more
semanticscholar   +1 more source

Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury

open access: yesJournal of Neuroinflammation, 2021
Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. Microglial/macrophage activation and neuroinflammation are key cellular events following TBI, but the regulatory and functional mechanisms are still not well understood ...
Haijian Wu   +14 more
semanticscholar   +1 more source

A New Sustainability Model – A Four Essential Quadrants Framework

open access: yesEconomics and Culture, 2021
Research purpose. This paper will present contemporary ideas on how, when, and where the four quadrants are vital to the sustainability of an organization and central to the future of the entity.
Fioravante Philip L.
doaj   +1 more source

Regulatory Effects of Quercetin on M1/M2 Macrophage Polarization and Oxidative/Antioxidative Balance

open access: yesNutrients, 2021
Macrophage polarization plays essential and diverse roles in most diseases, such as atherosclerosis, adipose tissue inflammation, and insulin resistance.
Cheng‐Fang Tsai   +7 more
semanticscholar   +1 more source

Work–Life Balance, Supervisor Support, and Life Satisfaction in the Higher Education Sector

open access: yesActa Universitatis Sapientiae: Economics and Business, 2023
The study explores the relationship between work–life balance and supervisor support in the Indian higher education sector. More specifically, the study explores the effects of supervisor support on the work–life balance of female employees working in ...
Wani Ambreen Khursheed
doaj   +1 more source

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