Results 101 to 110 of about 879,513 (265)

Adiponectin primes human monocytes into alternative anti-inflammatory M2 macrophages

, 2010
Altered macrophage kinetics is a pivotal mechanism of visceral obesity-induced inflammation and cardiometabolic risk. Because monocytes can differentiate into either proatherogenic M1 macrophages or anti-inflammatory M2 macrophages, approaches that limit
Paul E. Szmitko, Subodh Verma, Praphulla C. Shukla, Lawrence Chan, Mohammed Al-Omran, Krishna K. Singh, Yi Pan, Adrian Quan, Milan Gupta, Fina Lovren, Hwee Teoh   +10 more
core   +1 more source

Table_2_A Population of M2 Macrophages Associated With Bone Formation.docx

, 2021
We previously identified transient brown adipocyte-like cells associated with heterotopic ossification (HO). These ancillary cells support new vessel synthesis essential to bone formation.
Elizabeth Olmsted-Davis (11552029), Elizabeth Salisbury (15512), Zbigniew Gugala (11552032), Alan R. Davis (11552035), Julio Mejia (4282399)   +4 more
core   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

M2 macrophages and their role in rheumatic diseases

, 2019
As a component of the innate immune system, macrophages play a crucial role in host defense against a variety of microbes. Conventionally, macrophages have been classified as M1 and M2 depending on their phenotype and role in immune regulation.
Amita Aggarwal, Aggarwal, Amita, Bhattacharya, Shruti, Shruti Bhattacharya   +3 more
core   +1 more source

Effects of Angelica polysaccharide on differentiation and function in M2 macrophages

陆军军医大学学报
Objective To investigate the effect of Angelica polysaccharide (APS) on the differentiation and function of M2 macrophages and underlying molecular mechanism.
ZHANG Ke, CUI Zhao, QIN Yahan
doaj   +1 more source

TLR-3 Stimulation Skews M2 Macrophages to M1 Through IFN-αβ Signaling and Restricts Tumor Progression

Frontiers in Immunology, 2018
During tumor progression, macrophages shift their protective M1-phenotype to pro-tumorigenic M2-subtype. Therefore, conversion of M2 to M1 phenotype may be a potential therapeutic intervention.
Aurobind Vidyarthi, Aurobind Vidyarthi, Nargis Khan, Tapan Agnihotri, Shikha Negi, Deepjyoti K. Das, Mohammad Aqdas, Deepyan Chatterjee, Oscar R. Colegio, Manoj K. Tewari, Javed N. Agrewala, Javed N. Agrewala   +11 more
doaj   +1 more source

Water‐Activated Phospholipid Phase‐Separation Gel as an Immunomodulatory Anti‐Adhesion Barrier for Postoperative Adhesion Prevention

Advanced Healthcare Materials, EarlyView.
A water‐activated phospholipid phase‐separation gel is repurposed as a drug‐free surgical barrier for postoperative adhesion prevention. Propylene glycol promotes rapid lamellar gel reinforcement, prolonged local retention, and tissue coverage, while phosphatidylcholine‐mediated immunomodulation suppresses inflammatory and fibrotic responses. This dual‐
Jong‐Ju Lee, Yulseung Sung, Yeji Kim, Heesang Yang, Suyeon Pyo, Byeol Yun, Sung‐Joo Hwang   +6 more
wiley   +1 more source

M2 and monetary policy [PDF]

Consistent with its mandate in the Humphrey-Hawkins Act of 1978, the Federal Reserve System each year sets a calendar-year target for the monetary aggregate M2.
Robert L. Hetzel
core  

Proteomic characterization of human proinflammatory M1 and anti-inflammatory M2 macrophages and their response to Candida albicans

, 2014
In response to different stimuli, macrophages can differentiate into either a pro-inflammatory subtype (M1, classically activated macrophages) or acquire an anti-inflammatory phenotype (M2, alternatively activated macrophages).
Molero Martín-Portugués, María Gloria, Reales Calderón, José Antonio, Corbí, Ángel L., Aguilera Montilla, Noemí, Gil , Concha   +4 more
core   +1 more source

Exosomal NGFR derived from gastric cancer drives PANoptosis of M2 macrophages by activating RIPK1 via phosphorylation

Journal of Radiation Research and Applied Sciences
Objective: Gastric cancer (GC) is the fifth most common cancer with a high mortality rate. Exploration of therapeutic targets to develop effective strategies for GC treatment is urgent.
Huiru Yang, Zhekai Zhang, Liang Wang, Zhen Liu, Quanhui Chen, Yang Li, Hua Xue, Haifeng Jin   +7 more
doaj   +1 more source