Results 1 to 10 of about 159,735 (119)

Identification and validation of M2 macrophage-related genes in endometriosis

Heliyon, 2023
Aims: M2 macrophage is believed to play an important role in the development of endometriosis. This study aimed to identify several key genes related to the M2 macrophage in endometriosis.
Hongyan Ding, Hongge Xu, Ting Zhang, Can Shi   +3 more
doaj   +1 more source

Ratio of CD68/CD163 in Breast Carcinoma with and without Axillary Lymph Node Metastatic

Folia Medica Indonesiana, 2021
Tumor and its microenvironment can interact each other. Macrophage is part of tumor microenvironment. New drugs targeting specific superficial receptor of macrophage or cytokine of macrophage polarization have been found.
Priangga Adi Wiratama, Willy Sandhika
doaj   +1 more source

Differential polarization and the expression of efferocytosis receptor MerTK on M1 and M2 macrophages isolated from coronary artery disease patients

BMC Immunology, 2021
Background Differential polarization of macrophage into M1 and M2 mediates atherosclerotic plaque clearance through efferocytosis. Higher expression of Mer proto-oncogene tyrosine kinase (MerTK) on M2 macrophage helps in maintaining macrophage ...
Fatin Najiah Mohd Idrus, Nurul Shuhadah Ahmad, Chee Hock Hoe, Maryam Azlan, Farisha Alia Norfuad, Zurkurnai Yusof, Wan Yus Haniff Wan Isa, Akbar Ali Mohamed Ali, Get Bee Yvonne-Tee   +8 more
doaj   +1 more source

Lactate promotes Salmonella intracellular replication and systemic infection via driving macrophage M2 polarization

Microbiology Spectrum, 2023
Salmonella is one of the most important enteric pathogens worldwide, which is able to cause lethal systemic infection via survival and replication in host macrophages.
Xinyue Wang, Bin Yang, Shuangshuang Ma, Xiaolin Yan, Shuai Ma, Hongmin Sun, Yuyang Sun, Lingyan Jiang   +7 more
doaj   +1 more source

Macrophage M2 Co-expression Factors Correlate With the Immune Microenvironment and Predict Outcome of Renal Clear Cell Carcinoma

Frontiers in Genetics, 2021
Purpose: In the tumor microenvironment, the functional differences among various tumor-associated macrophages (TAM) are not completely clear. Tumor-associated macrophages are thought to promote the progression of cancer. This article focuses on exploring
Yutao Wang, Kexin Yan, Jiaxing Lin, Jun Li, Jianbin Bi   +4 more
doaj   +1 more source

Exosomes derived from M2 Macrophages Improve Angiogenesis and Functional Recovery after Spinal Cord Injury through HIF-1α/VEGF Axis

Brain Sciences, 2022
Exosomes are nano-sized vesicles that contain a variety of mRNAs, miRNAs, and proteins. They are capable of being released by a variety of cells and are essential for cell–cell communication.
Jiang-Hu Huang, Hang He, Yong-Neng Chen, Zhen Liu, Manini Daudi Romani, Zhao-Yi Xu, Yang Xu, Fei-Yue Lin   +7 more
doaj   +1 more source

Selective M1 macrophage polarization in granuloma-positive and granuloma-negative Crohn's disease, in comparison to intestinal tuberculosis [PDF]

Intestinal Research, 2018
Background/AimsClassical M1 macrophage activation exhibits an inflammatory phenotype while alternative M2 macrophage activation exhibits an anti-inflammatory phenotype.
Prasenjit Das, Ritika Rampal, Sonakshi Udinia, Tarun Kumar, Sucharita Pilli, Nahid Wari, Imtiaz Khan Ahmed, Saurabh Kedia, Siddhartha Datta Gupta, Dhiraj Kumar, Vineet Ahuja   +10 more
doaj   +1 more source

Exosomal DLX6-AS1 from hepatocellular carcinoma cells induces M2 macrophage polarization to promote migration and invasion in hepatocellular carcinoma through microRNA-15a-5p/CXCL17 axis

Journal of Experimental & Clinical Cancer Research, 2021
Background Hepatocellular carcinoma (HCC) cells-secreted exosomes (exo) could stimulate M2 macrophage polarization and promote HCC progression, but the related mechanism of long non-coding RNA distal-less homeobox 6 antisense 1 (DLX6-AS1) with HCC-exo ...
Lin-pei Wang, Jing Lin, Xiao-qiu Ma, Dong-yao Xu, Chun-feng Shi, Wei Wang, Xiao-jie Jiang   +6 more
doaj   +1 more source

(−)-Guaiol inhibit epithelial-mesenchymal transition in lung cancer via suppressing M2 macrophages mediated STAT3 signaling pathway

Heliyon, 2023
In the context of cancer expansion, epithelial-mesenchymal transition (EMT) plays an essential role in driving invasion and metastasis potential of cancer cells.
Yajuan Cao, Yonghui Wu, Hongbin Tu, Zhan Gu, Fengzhi Yu, Weiling Huang, Liping Shen, Lixin Wang, Yan Li   +8 more
doaj   +1 more source

A Benzenediamine Analog FC-99 Drives M2 Macrophage Polarization and Alleviates Lipopolysaccharide- (LPS-) Induced Liver Injury

Mediators of Inflammation, 2019
Macrophages have variable functional phenotypes, high diversity, and plasticity and are involved in the pathogenesis of sepsis-induced liver injury. Alteration of macrophage polarization through activated (M1) macrophage to alternatively activated (M2 ...
Wei Gong, Haiyan Zhu, Li Lu, Yayi Hou, Huan Dou   +4 more
doaj   +1 more source