Results 121 to 130 of about 7,801 (240)

Investigation of M3 muscarinic acetylcholine receptor expression in placentas of smoking women

open access: yesPerinatal Journal
Objective: This study examined M3 muscarinic acetylcholine receptor expression in placentas of women who smoked during pregnancy and explored the affected signaling pathways via network and functional annotation analyses. Methods: Placenta samples from 45 control subjects and 45 individuals who smoked during pregnancy were fixed in zinc-formalin and em-
Ege, Serhat   +6 more
openaire   +2 more sources

Mice Lacking M1 and M3 Muscarinic Acetylcholine Receptors Have Impaired Odor Discrimination and Learning [PDF]

open access: gold, 2017
Wilson Chan   +7 more
openalex   +1 more source

Effects of Nerve Growth Factor shRNA Inhibition on Asthma Phenotypes in a Mouse Model of Asthma

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2018
Nerve growth factor (NGF) plays an important role in airway hyper-responsiveness (AHR). In this study, we aimed at investigating the effect of NGF inhibition on AHR and other asthma phenotypes in a mouse model of asthma.
Jinhong Wu   +3 more
doaj  

A novel M3 muscarinic acetylcholine receptor is expressed in chick atrium and ventricle.

open access: yesJournal of Biological Chemistry, 1994
Prior studies have suggested that heart expresses only the M2 isoform of the muscarinic receptor (Peralta, E.G., Ashkenazi, A., Winslow, J.W., Smith, D.H., Ramachandran, J., and Capon, D.J. (1987) EMBO J. 6, 3923-3929). Tietje and Nathanson (Tietje, K.M., and Nathanson, N. M. (1991) J. Biol. Chem.
A P, Gadbut, J B, Galper
openaire   +2 more sources

RT-PCR reveals muscarinic acetylcholine receptor mRNA in the pre-Bötzinger complex

open access: yes, 2001
Muscarinic receptors mediate the postsynaptic excitatory effects of acetylcholine (ACh) on inspiratory neurons in the pre-Bötzinger complex (pre-BötC), the hypothesized site for respiratory rhythm generation.
Cindy H. Huang   +5 more
core   +1 more source

Characterization of the rat m3 muscarinic acetylcholine receptor produced in insect cells infected with recombinant baculovirus

open access: yes, 1995
The m3 muscarinic acetylcholine receptor from rat heterologously produced in insect cells after infection with a recombinant baculovirus has an apparent molecular mass of approximately 75 kDa.
Subhash Vasudevan   +11 more
core   +1 more source

Muscarinic Agonist-Mediated Heterologous Desensitization in Isolated Ileum Requires Activation of Both Muscarinic M2 and M3 Receptors

open access: yes, 2004
We investigated the subtypes of the muscarinic receptor mediating short-term heterologous desensitization in the isolated ileum. Treatment of the ileum from C57BL/6 mice with acetylcholine (30 μM) for 20 min caused a subsequent decrease in contractile ...
Shehnaz, Darakhshanda   +6 more
core   +1 more source

High expression of muscarinic acetylcholine receptor 3 predicts poor prognosis in patients with pancreatic ductal adenocarcinoma

open access: yes, 2016
Aims: Recent studies showed that muscarinic acetylcholine receptor 3 (M3), as a muscarinic acetylcholine receptor family member that plays an important role in normal physiological function, is engaged in cancer progression.
Xiu, Dianrong   +8 more
core   +1 more source

Molecular studies of cross-talk between M2 and M3 muscarinic acetylcholine receptor subtypes

open access: yes, 2001
Many cell-types in the body express mixed populations of muscarinic acetylcholine (mACh) receptors. For example, various types of smooth muscle express both M2 and M3 mACh receptors.
David Charles. Hornigold (7684124)
core  

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