Results 11 to 20 of about 46,200 (286)
Transcriptome-Wide m6A Methylome and m6A-Modified Gene Analysis in Asthma
Frontiers in Cell and Developmental Biology, 2022 N6-methyladenosine (m6A) modification is one of the most prevalent RNA modification forms and is an important posttranscriptional mechanism for regulating genes. In previous research, we found that m6A regulator–mediated RNA methylation modification was involved in asthma; however, the specific modified genes are not clear.
Deyang Sun +9 more
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Epitranscriptomics in the Heart: a Focus on m6A [PDF]
Current Heart Failure Reports, 2020 Post-transcriptional modifications are key regulators of gene expression that allow the cell to respond to environmental stimuli. The most abundant internal mRNA modification is N6-methyladenosine (m6A), which has been shown to be involved in the regulation of RNA splicing, localization, translation, and decay.
Jacob Z, Longenecker +4 more
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Eye Movements Actively Reinstate Spatiotemporal Mnemonic Content
Vision, 2019 Eye movements support memory encoding by binding distinct elements of the visual world into coherent representations. However, the role of eye movements in memory retrieval is less clear.
Jordana S. Wynn +2 more
doaj +1 more source
m6a RNA methylation: the implications for health and disease [PDF]
, 2014 The recent resurgence of interest in m6a has been spurred by some intriguing findings detailing the effects and dynamics of this epigenetic modification.
McGuinness, D., Mcguinness, D.H.
core +1 more source
METTL3 regulates WTAP protein homeostasis [PDF]
, 2018 The Wilms tumor 1 (WT1)-associated protein (WTAP) is upregulated in many tumors, including, acute myeloid leukemia (AML), where it plays an oncogenic role by interacting with different proteins involved in RNA processing and cell proliferation.
Capuano, Ernestina +8 more
core +2 more sources
Modulation of internuclear communication in multinuclear Ruthenium(II) polypyridyl complexes [PDF]
, 2003 The syntheses and characterisation of a series of mononuclear and dinuclear ruthenium polypyridyl complexes based on the bridging ligands 1,3-bis-[5-(2-pyridyl)-1H-1,2,4-triazol-3-yl]benzene, 1,4-bis-[5-(2-pyridyl)-1H-1,2,4-triazol-3-yl]benzene, 2,5-bis-[
Adrian Guckian +4 more
core +2 more sources
Frontiers in Bioscience-Landmark, 2022 N6-methyladenosine (m6A) methylation/modification plays a critical role in various biological processes through post-transcriptional ribonucleic acid (RNA) modification, which involves RNA processing, nuclear export, translation and decay.
Xiaohua Li +8 more
doaj +1 more source
Epigenetics, 2023 Cerebral ischaemiareperfusion injury is an important pathological process in nervous system diseases during which neurons undergo oxygenglucose deprivation and reoxygenation (OGD/R) injury. No study has used epitranscriptomics to explore the characteristics and mechanism of injury.
Chi Zhang +12 more
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Nature Chemical Biology, 2020 The biological function and origin of m6A in DNA have been widely debated. A new study demonstrates that the majority of m6A in DNA originates from RNA catabolism via a nucleotide salvage pathway.
Spingardi, P, Kriaucionis, S
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Modulation of circRNA Metabolism by m6A Modification [PDF]
Cell Reports, 2020 N6-methyladenosine (m6A) is an RNA modification well-known for its contribution to different processes controlling RNA metabolism, including splicing, stability, and translation of mRNA. Conversely, the role of m6A on the biogenesis and function of circular RNAs (circRNAs) has yet to be addressed.
Di Timoteo G. +10 more
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