Results 31 to 40 of about 36,922 (295)

CTLife/m6A-SAC-seq: version 1.1

open access: yes, 2022
Perl, Bash shell, and R scripts for m6A-SAC-seq data ...
Source Codes for Computational and Theoretical Life Science
core   +1 more source

Crosstalk between m6A mRNAs and m6A circRNAs and the time-specific biogenesis of m6A circRNAs after OGD/R in primary neurons

open access: yesEpigenetics, 2023
Cerebral ischaemiareperfusion injury is an important pathological process in nervous system diseases during which neurons undergo oxygenglucose deprivation and reoxygenation (OGD/R) injury. No study has used epitranscriptomics to explore the characteristics and mechanism of injury.
Chi Zhang   +12 more
openaire   +3 more sources

Modulation of circRNA Metabolism by m6A Modification [PDF]

open access: yesCell Reports, 2020
N6-methyladenosine (m6A) is an RNA modification well-known for its contribution to different processes controlling RNA metabolism, including splicing, stability, and translation of mRNA. Conversely, the role of m6A on the biogenesis and function of circular RNAs (circRNAs) has yet to be addressed.
Di Timoteo G.   +10 more
openaire   +3 more sources

Comprehensive analysis of the transcriptome-wide m6A methylome in colorectal cancer by MeRIP sequencing

open access: yesEpigenetics, 2021
Accumulating evidence has demonstrated that N6-methyladenosine (m6A) plays important roles in various cancers, making it essential to profile m6A modifications at a transcriptome-wide scale in colorectal cancer (CRC).
Zhen Zhang   +10 more
doaj   +1 more source

m6 RNA methylation: an emerging common target in the immune response to cancer and severe acute respiratory syndrome-coronavirus-2 infection

open access: yesExploration of Medicine, 2023
m6A RNA methylation, a predominant type of RNA modification, is involved in regulating mRNA splicing, stability, and translation as well as the interaction between nucleoproteins and noncoding RNAs.
Hiromichi Sato   +10 more
doaj   +1 more source

How m6A sneaks into DNA

open access: yesNature Chemical Biology, 2020
The biological function and origin of m6A in DNA have been widely debated. A new study demonstrates that the majority of m6A in DNA originates from RNA catabolism via a nucleotide salvage pathway.
Spingardi, P, Kriaucionis, S
openaire   +2 more sources

Table_1_Dynamic m6A mRNA Methylation Reveals the Role of METTL3/14-m6A-MNK2-ERK Signaling Axis in Skeletal Muscle Differentiation and Regeneration.XLSX

open access: yes, 2021
N6-methyladenosine (m6A) RNA methylation has emerged as an important factor in various biological processes by regulating gene expression. However, the dynamic profile, function and underlying molecular mechanism of m6A modification during skeletal ...
Shuang Tao (11510260)   +12 more
core   +1 more source

METTL3-mediated m6A modification of lnc KCNQ1OT1 promotes doxorubicin resistance in breast cancer by regulating miR-103a-3p/MDR1 axis

open access: yesEpigenetics, 2023
Doxorubicin (DOX) resistance in breast cancer (BC) poses a huge challenge for the therapeutic effect on BC. Lnc KCNQ1OT1 play crucial roles in chemotherapy resistance.
Zhiyang Zhou   +4 more
doaj   +1 more source

Integration Analysis of m6A Regulators and m6A-Related Genes in Hepatocellular Carcinoma

open access: yesBIO Integration, 2021
Abstract Background: N6-Methyladenosine (m6A) RNA methylation of eukaryotic mRNA is involved in the progression of various tumors. We aimed to investigate m6A-related genes and m6A regulators in hepatocellular carcinoma (HCC) and their association with prognosis in HCC.
Jingdun Xie   +7 more
openaire   +2 more sources

Table_7_Dynamic m6A mRNA Methylation Reveals the Role of METTL3/14-m6A-MNK2-ERK Signaling Axis in Skeletal Muscle Differentiation and Regeneration.XLS

open access: yes, 2021
N6-methyladenosine (m6A) RNA methylation has emerged as an important factor in various biological processes by regulating gene expression. However, the dynamic profile, function and underlying molecular mechanism of m6A modification during skeletal ...
Shuang Tao (11510260)   +12 more
core   +1 more source

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