Results 31 to 40 of about 30,145 (267)
Journal of Inflammation Research, 2023 Haishi Zheng,1,2 Yirixiati Aihaiti,2 Yongsong Cai,2 Qiling Yuan,2 Mingyi Yang,2 Zheng Li,2 Ke Xu,2 Peng Xu1,2 1Department of Orthopedics, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China; 2Department of Joint ...
Zheng H +7 more
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Epigenetics, 2023 The most prominent RNA modification – N6-methyladenosine (m6A) – affects gene regulation and cancer progression. The extent and effect of m6A on long non-coding RNAs (lncRNAs) is, however, still not clear. The most established method for m6A detection is
Raulas Krusnauskas +4 more
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Identifying cortical specific long noncoding RNAs modified by m6A RNA methylation in mouse brains
Epigenetics, 2021 Proper development of the mammalian cerebral cortex relies on precise gene expression regulation. Increasing evidence shows that cortical development is regulated by both mRNAs and long noncoding RNAs (lncRNAs), which also are modified by N6 ...
Yanzhen Nie +6 more
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Readers of the m6A epitranscriptomic code
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2019 N6-methyl adenosine (m6A) is the most prevalent and evolutionarily conserved, modification of polymerase II transcribed RNAs. By post-transcriptionally controlling patterns of gene expression, m6A deposition is crucial for organism reproduction, development and likely stress responses.
Berlivet, Soizik +3 more
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Interactive influences of prior knowledge on episodic memory
iScienceSummary: Many species adapt to their environments by accruing relevant knowledge and expertise, which in turn shapes memory formation. Human experts remember items in their field better than novices, but different types of knowledge or exposure influence
Erik A. Wing +2 more
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Exploring the Epigenetic Regulatory Role of m6A-Associated SNPs in Type 2 Diabetes Pathogenesis
Pharmacogenomics and Personalized Medicine, 2021 Miao Chen,1,2 Weimin Lin,1 Jianru Yi,1,2 Zhihe Zhao1,2 1State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, People’s Republic of China; 2Department ...
Chen M, Lin W, Yi J, Zhao Z
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N6-Methyladenosine (m6A) Modification in Natural Immune Cell-Mediated Inflammatory Diseases
Journal of Innate Immunity, 2023 The post-transcriptional N6-methyladenosine (m6A) modification of RNA influences stability, transport, and translation with implications for various physiological and pathological processes.
Yan Teng, Jin Yi, Junnian Chen, Lu Yang
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The m6A Methyltransferase METTL3 Is Functionally Implicated in DLBCL Development by Regulating m6A Modification in PEDF [PDF]
Frontiers in Genetics, 2020 Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of lymphoma, whose treatment still has a major challenge of achieving a satisfactory curative effect. The underlying mechanisms also have not been fully illustrated. N 6-Methyladenosine (m6A) has been identified as the most prevalent internal modification of mRNAs present in eukaryotes ...
Yingying Cheng +3 more
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Neuroelectric Correlates of Perceptual Awareness During the Auditory Attentional Blink
Brain SciencesBackground: Perceptual awareness refers to the conscious detection and identification of a sensory event. In electrophysiological studies, it is associated with a modality-specific negative-going event-related potential, which can be observed as early as
Claude Alain +4 more
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Crosstalk between RNA Metabolism and Cellular Stress Responses during Zika Virus Replication
Pathogens, 2020 Zika virus (ZIKV) is a mosquito-borne virus associated with neurological disorders such as Guillain-Barré syndrome and microcephaly. In humans, ZIKV is able to replicate in cell types from different tissues including placental cells, neurons, and ...
Aarón Oyarzún-Arrau +4 more
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