Results 51 to 60 of about 40,511 (310)

The m6A/m1A/m5C-Related Methylation Modification Patterns and Immune Landscapes in Rheumatoid Arthritis and Osteoarthritis Revealed by Microarray and Single-Cell Transcriptome

Journal of Inflammation Research, 2023
Haishi Zheng,1,2 Yirixiati Aihaiti,2 Yongsong Cai,2 Qiling Yuan,2 Mingyi Yang,2 Zheng Li,2 Ke Xu,2 Peng Xu1,2 1Department of Orthopedics, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China; 2Department of Joint ...
Zheng H, Aihaiti Y, Cai Y, Yuan Q, Yang M, Li Z, Xu K, Xu P   +7 more
doaj  

Identification and comparison of m6A modifications in glioblastoma non-coding RNAs with MeRIP-seq and Nanopore dRNA-seq

Epigenetics, 2023
The most prominent RNA modification – N6-methyladenosine (m6A) – affects gene regulation and cancer progression. The extent and effect of m6A on long non-coding RNAs (lncRNAs) is, however, still not clear. The most established method for m6A detection is
Raulas Krusnauskas, Rytis Stakaitis, Giedrius Steponaitis, Kristian Almstrup, Paulina Vaitkiene   +4 more
doaj   +1 more source

m6A-ELISA, a simple method for quantifying N6-methyladenosine from mRNA populations.

, 2023
N6-methyladenosine (m6A) is a widely studied and abundant RNA modification. The m6A mark regulates the fate of RNAs in various ways, which in turn, drives changes in cell physiology, development, and disease pathology.
Imke Ensinck (14263964), Folkert van Werven (15336820), Theodora Sideri (41320), Patrick Toolan-Kerr (8864216), Miha Modic (7016804), Charlotte Capitanchik (5577323), Claudia Vivori (13828039)   +6 more
core   +1 more source

Readers of the m6A epitranscriptomic code

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2019
N6-methyl adenosine (m6A) is the most prevalent and evolutionarily conserved, modification of polymerase II transcribed RNAs. By post-transcriptionally controlling patterns of gene expression, m6A deposition is crucial for organism reproduction, development and likely stress responses.
Berlivet, Soizik, Scutenaire, Jérémy, Deragon, Jean-Marc, Bousquet-Antonelli, Cécile   +3 more
openaire   +4 more sources

Neuroelectric Correlates of Perceptual Awareness During the Auditory Attentional Blink

Brain Sciences
Background: Perceptual awareness refers to the conscious detection and identification of a sensory event. In electrophysiological studies, it is associated with a modality-specific negative-going event-related potential, which can be observed as early as
Claude Alain, Mary O’Neil, Lori J. Bernstein, Dawei Shen, Bernhard Ross   +4 more
doaj   +1 more source

Identifying cortical specific long noncoding RNAs modified by m6A RNA methylation in mouse brains

Epigenetics, 2021
Proper development of the mammalian cerebral cortex relies on precise gene expression regulation. Increasing evidence shows that cortical development is regulated by both mRNAs and long noncoding RNAs (lncRNAs), which also are modified by N6 ...
Yanzhen Nie, Geng.G. Tian, Longbin Zhang, Trevor Lee, Zhen Zhang, Jing Li, Tao Sun   +6 more
doaj   +1 more source

m6A-Seq data (analysis of GSE37005)

, 2017
This dataset contains analysis of sequencing data from m6A IP (GEO accession: GSE37005)
Thomas Ni (2289073)
core   +1 more source

Table_1_MEF2C Expression Is Regulated by the Post-transcriptional Activation of the METTL3-m6A-YTHDF1 Axis in Myoblast Differentiation.DOCX

, 2022
N6-methyladenosine (m6A) plays an essential role in regulating gene expression. However, the effect of m6A on skeletal myoblast differentiation and the underlying mechanisms are still unclear.
Chugang Mei (4823697), Sayed Haidar Abbas Raza (8452353), Xinran Yang (11795426), Linsen Zan (727236), Yue Ning (429704)   +4 more
core   +1 more source

Interactive influences of prior knowledge on episodic memory

iScience
Summary: Many species adapt to their environments by accruing relevant knowledge and expertise, which in turn shapes memory formation. Human experts remember items in their field better than novices, but different types of knowledge or exposure influence
Erik A. Wing, Asaf Gilboa, Jennifer D. Ryan   +2 more
doaj   +1 more source

Exploring the Epigenetic Regulatory Role of m6A-Associated SNPs in Type 2 Diabetes Pathogenesis

Pharmacogenomics and Personalized Medicine, 2021
Miao Chen,1,2 Weimin Lin,1 Jianru Yi,1,2 Zhihe Zhao1,2 1State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, People’s Republic of China; 2Department ...
Chen M, Lin W, Yi J, Zhao Z
doaj