Results 51 to 60 of about 36,922 (295)

Readers of the m6A epitranscriptomic code

open access: yesBiochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2019
N6-methyl adenosine (m6A) is the most prevalent and evolutionarily conserved, modification of polymerase II transcribed RNAs. By post-transcriptionally controlling patterns of gene expression, m6A deposition is crucial for organism reproduction, development and likely stress responses.
Berlivet, Soizik   +3 more
openaire   +4 more sources

The m6A Methyltransferase METTL3 Is Functionally Implicated in DLBCL Development by Regulating m6A Modification in PEDF [PDF]

open access: yesFrontiers in Genetics, 2020
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of lymphoma, whose treatment still has a major challenge of achieving a satisfactory curative effect. The underlying mechanisms also have not been fully illustrated. N 6-Methyladenosine (m6A) has been identified as the most prevalent internal modification of mRNAs present in eukaryotes ...
Yingying Cheng   +3 more
openaire   +3 more sources

Table_10_Dynamic m6A mRNA Methylation Reveals the Role of METTL3/14-m6A-MNK2-ERK Signaling Axis in Skeletal Muscle Differentiation and Regeneration.XLS

open access: yes, 2021
N6-methyladenosine (m6A) RNA methylation has emerged as an important factor in various biological processes by regulating gene expression. However, the dynamic profile, function and underlying molecular mechanism of m6A modification during skeletal ...
Shuang Tao (11510260)   +12 more
core   +1 more source

Table_5_Dynamic m6A mRNA Methylation Reveals the Role of METTL3/14-m6A-MNK2-ERK Signaling Axis in Skeletal Muscle Differentiation and Regeneration.XLS

open access: yes, 2021
N6-methyladenosine (m6A) RNA methylation has emerged as an important factor in various biological processes by regulating gene expression. However, the dynamic profile, function and underlying molecular mechanism of m6A modification during skeletal ...
Shuang Tao (11510260)   +12 more
core   +1 more source

The m6A/m1A/m5C-Related Methylation Modification Patterns and Immune Landscapes in Rheumatoid Arthritis and Osteoarthritis Revealed by Microarray and Single-Cell Transcriptome

open access: yesJournal of Inflammation Research, 2023
Haishi Zheng,1,2 Yirixiati Aihaiti,2 Yongsong Cai,2 Qiling Yuan,2 Mingyi Yang,2 Zheng Li,2 Ke Xu,2 Peng Xu1,2 1Department of Orthopedics, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China; 2Department of Joint ...
Zheng H   +7 more
doaj  

Table_2_Dynamic m6A mRNA Methylation Reveals the Role of METTL3/14-m6A-MNK2-ERK Signaling Axis in Skeletal Muscle Differentiation and Regeneration.XLSX

open access: yes, 2021
N6-methyladenosine (m6A) RNA methylation has emerged as an important factor in various biological processes by regulating gene expression. However, the dynamic profile, function and underlying molecular mechanism of m6A modification during skeletal ...
Shuang Tao (11510260)   +12 more
core   +1 more source

m6A-ELISA, a simple method for quantifying N6-methyladenosine from mRNA populations.

open access: yes, 2023
N6-methyladenosine (m6A) is a widely studied and abundant RNA modification. The m6A mark regulates the fate of RNAs in various ways, which in turn, drives changes in cell physiology, development, and disease pathology.
Imke Ensinck (14263964)   +6 more
core   +1 more source

Interactive influences of prior knowledge on episodic memory

open access: yesiScience
Summary: Many species adapt to their environments by accruing relevant knowledge and expertise, which in turn shapes memory formation. Human experts remember items in their field better than novices, but different types of knowledge or exposure influence
Erik A. Wing   +2 more
doaj   +1 more source

Exploring the Epigenetic Regulatory Role of m6A-Associated SNPs in Type 2 Diabetes Pathogenesis

open access: yesPharmacogenomics and Personalized Medicine, 2021
Miao Chen,1,2 Weimin Lin,1 Jianru Yi,1,2 Zhihe Zhao1,2 1State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, People’s Republic of China; 2Department ...
Chen M, Lin W, Yi J, Zhao Z
doaj  

Potential Impact of N6-Methyladenosine RNA Methylation on Vision Function and the Pathological Processes of Ocular Diseases: New Discoveries and Future Perspectives

open access: yesFrontiers in Bioscience-Landmark, 2022
N6-methyladenosine (m6A) methylation/modification plays a critical role in various biological processes through post-transcriptional ribonucleic acid (RNA) modification, which involves RNA processing, nuclear export, translation and decay.
Xiaohua Li   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy