Results 61 to 70 of about 40,511 (310)
N6-methyladenosine (m6A) plays an essential role in regulating gene expression. However, the effect of m6A on skeletal myoblast differentiation and the underlying mechanisms are still unclear.
Chugang Mei (4823697) +4 more
core +1 more source
Crosstalk between RNA Metabolism and Cellular Stress Responses during Zika Virus Replication
Zika virus (ZIKV) is a mosquito-borne virus associated with neurological disorders such as Guillain-Barré syndrome and microcephaly. In humans, ZIKV is able to replicate in cell types from different tissues including placental cells, neurons, and ...
Aarón Oyarzún-Arrau +4 more
doaj +1 more source
N6-Methyladenosine (m6A) Modification in Natural Immune Cell-Mediated Inflammatory Diseases
The post-transcriptional N6-methyladenosine (m6A) modification of RNA influences stability, transport, and translation with implications for various physiological and pathological processes.
Yan Teng, Jin Yi, Junnian Chen, Lu Yang
doaj +1 more source
N6-methyladenosine (m6A) plays an essential role in regulating gene expression. However, the effect of m6A on skeletal myoblast differentiation and the underlying mechanisms are still unclear.
Chugang Mei (4823697) +4 more
core +1 more source
The Role of M6a in Angiogenesis and Vascular Diseases
Angiogenesis, whether physiological or pathological, plays a pivotal role in various physiological and disease conditions. This intricate process relies on a complex and meticulously orchestrated signal transduction network that connects endothelial cells, their associated parietal cells (VSMCs and pericytes), and various other cell types, including ...
Chen, Ke, Li, Wen-Dong, Li, Xiao-Qiang
openaire +2 more sources
The m6A Methyltransferase METTL3 Is Functionally Implicated in DLBCL Development by Regulating m6A Modification in PEDF [PDF]
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of lymphoma, whose treatment still has a major challenge of achieving a satisfactory curative effect. The underlying mechanisms also have not been fully illustrated. N 6-Methyladenosine (m6A) has been identified as the most prevalent internal modification of mRNAs present in eukaryotes ...
Yingying Cheng +3 more
openaire +3 more sources
Perception and encoding of narrative events during continuous speech listening in background noise
Everyday speech comprehension involves interpreting overarching themes as they unfold continuously overtime and structuring experiences for effective encoding and future recall. Characterizing downstream cognition, particularly how the brain perceptually
Ryan A. Panela +4 more
doaj +1 more source
N6-methyladenosine (m6A) plays an essential role in regulating gene expression. However, the effect of m6A on skeletal myoblast differentiation and the underlying mechanisms are still unclear.
Chugang Mei (4823697) +4 more
core +1 more source
The importance of m6A topology in chicken embryo mRNA: a precise mapping of m6A at the conserved chicken β-actin zipcode [PDF]
N6-methyladenosine (m6A) in mRNA regulates almost every stage in the mRNA life cycle, and the development of methodologies for the high-throughput detection of methylated sites in mRNA using m6A-specific methylated RNA immunoprecipitation with next ...
Bodi, Zsuzsa +21 more
core +1 more source
SEC Mediates m6A Deposition and Transcription Pause Release to Drive Cell Identity Transition [PDF]
The SEC promotes cell identity transitions by facilitating transcription pause release at key identity‐associated genes, including Klf4 and Myc during iPSC reprogramming and Nes and Tubb3 during ESC‐to‐neuroectodermal differentiation. During early iPSC reprogramming, this function additionally involves cooperation with METTL3‐associated m6A regulation.
Zhang Z +9 more
europepmc +2 more sources

