Results 21 to 30 of about 30,145 (267)
RNA modification-mediated translational control in immune cells
RNA Biology, 2023 RNA modifications play a vital role in multiple pathways of mRNA metabolism, and translational regulation is essential for immune cells to promptly respond to stimuli and adapt to the microenvironment.
Yujuan Zhang, Weiguo Hu, Hua-Bing Li
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Eye Movements Actively Reinstate Spatiotemporal Mnemonic Content
Vision, 2019 Eye movements support memory encoding by binding distinct elements of the visual world into coherent representations. However, the role of eye movements in memory retrieval is less clear.
Jordana S. Wynn +2 more
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Frontiers in Bioscience-Landmark, 2022 N6-methyladenosine (m6A) methylation/modification plays a critical role in various biological processes through post-transcriptional ribonucleic acid (RNA) modification, which involves RNA processing, nuclear export, translation and decay.
Xiaohua Li +8 more
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Developmental Cognitive Neuroscience, 2019 Variability of neural signaling is an important index of healthy brain functioning, as is signal complexity, which relates to information processing capacity. Alterations in variability and complexity may underlie certain brain dysfunctions.
Amanda K. Easson, Anthony R. McIntosh
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Modulation of circRNA Metabolism by m6A Modification [PDF]
Cell Reports, 2020 N6-methyladenosine (m6A) is an RNA modification well-known for its contribution to different processes controlling RNA metabolism, including splicing, stability, and translation of mRNA. Conversely, the role of m6A on the biogenesis and function of circular RNAs (circRNAs) has yet to be addressed.
Di Timoteo G. +10 more
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Epigenetics, 2023 Cerebral ischaemiareperfusion injury is an important pathological process in nervous system diseases during which neurons undergo oxygenglucose deprivation and reoxygenation (OGD/R) injury. No study has used epitranscriptomics to explore the characteristics and mechanism of injury.
Chi Zhang +12 more
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Parkinson's Disease, 2013 Background. Parkinson’s disease (PD) is a neurodegenerative condition with complex subtleties, making it challenging for physicians to fully inform their patients.
Galit Kleiner-Fisman +2 more
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Nature Chemical Biology, 2020 The biological function and origin of m6A in DNA have been widely debated. A new study demonstrates that the majority of m6A in DNA originates from RNA catabolism via a nucleotide salvage pathway.
Spingardi, P, Kriaucionis, S
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Integration Analysis of m6A Regulators and m6A-Related Genes in Hepatocellular Carcinoma
BIO Integration, 2021 Abstract Background: N6-Methyladenosine (m6A) RNA methylation of eukaryotic mRNA is involved in the progression of various tumors. We aimed to investigate m6A-related genes and m6A regulators in hepatocellular carcinoma (HCC) and their association with prognosis in HCC.
Jingdun Xie +7 more
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An additional class of m6A readers [PDF]
Nature Cell Biology, 2018 N6-methyladenosine (m6A) mRNA modification influences mRNA fate by stimulating recruitment of m6A reader proteins. A previously unappreciated class of m6A reader proteins is now shown to use a common RNA-binding domain and flanking regions to selectively bind m6A-containing mRNAs, increasing their translation and stability.
Katherine I, Zhou, Tao, Pan
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