Results 21 to 30 of about 46,200 (286)
Integration Analysis of m6A Regulators and m6A-Related Genes in Hepatocellular Carcinoma
BIO Integration, 2021 Abstract Background: N6-Methyladenosine (m6A) RNA methylation of eukaryotic mRNA is involved in the progression of various tumors. We aimed to investigate m6A-related genes and m6A regulators in hepatocellular carcinoma (HCC) and their association with prognosis in HCC.
Jingdun Xie +7 more
openaire +2 more sources
Developmental Cognitive Neuroscience, 2019 Variability of neural signaling is an important index of healthy brain functioning, as is signal complexity, which relates to information processing capacity. Alterations in variability and complexity may underlie certain brain dysfunctions.
Amanda K. Easson, Anthony R. McIntosh
doaj +1 more source
An additional class of m6A readers [PDF]
Nature Cell Biology, 2018 N6-methyladenosine (m6A) mRNA modification influences mRNA fate by stimulating recruitment of m6A reader proteins. A previously unappreciated class of m6A reader proteins is now shown to use a common RNA-binding domain and flanking regions to selectively bind m6A-containing mRNAs, increasing their translation and stability.
Katherine I, Zhou, Tao, Pan
openaire +2 more sources
Form-factors and current correlators: chiral couplings L_10(mu) and C_87(mu) at NLO in 1/N(C) [PDF]
, 2008 Using the resonance chiral theory Lagrangian, we perform a calculation of the vector and axial-vector two-point functions at the next-to-leading order (NLO) in the 1/N(C) expansion.
Pich, A. +2 more
core +3 more sources
Parkinson's Disease, 2013 Background. Parkinson’s disease (PD) is a neurodegenerative condition with complex subtleties, making it challenging for physicians to fully inform their patients.
Galit Kleiner-Fisman +2 more
doaj +1 more source
Improved $\alpha^4$ Term of the Electron Anomalous Magnetic Moment [PDF]
, 2005 We report a new value of electron $g-2$, or $a_e$, from 891 Feynman diagrams of order $\alpha^4$. The FORTRAN codes of 373 diagrams containing closed electron loops have been verified by at least two independent formulations.
A. Petermann +16 more
core +1 more source
Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis [PDF]
, 2017 Circular RNAs (circRNAs) constitute a family of transcripts with unique structures and still largely unknown functions. Their biogenesis, which proceeds via a back-splicing reaction, is fairly well characterized, whereas their role in the modulation of ...
Andronache, Adrian +12 more
core +3 more sources
Epigenetics, 2023 The most prominent RNA modification – N6-methyladenosine (m6A) – affects gene regulation and cancer progression. The extent and effect of m6A on long non-coding RNAs (lncRNAs) is, however, still not clear. The most established method for m6A detection is
Raulas Krusnauskas +4 more
doaj +1 more source
Readers of the m6A epitranscriptomic code
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2019 N6-methyl adenosine (m6A) is the most prevalent and evolutionarily conserved, modification of polymerase II transcribed RNAs. By post-transcriptionally controlling patterns of gene expression, m6A deposition is crucial for organism reproduction, development and likely stress responses.
Berlivet, Soizik +3 more
openaire +4 more sources
The m6A Methyltransferase METTL3 Is Functionally Implicated in DLBCL Development by Regulating m6A Modification in PEDF [PDF]
Frontiers in Genetics, 2020 Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of lymphoma, whose treatment still has a major challenge of achieving a satisfactory curative effect. The underlying mechanisms also have not been fully illustrated. N 6-Methyladenosine (m6A) has been identified as the most prevalent internal modification of mRNAs present in eukaryotes ...
Yingying Cheng +3 more
openaire +3 more sources