Results 201 to 210 of about 63,662 (384)

Glycolysis induced by METTL14-related m6A methylation is essential for macrophage function and tumor progression in cervical cancer [PDF]

, 2022
Bingyu Wang, Xinlin Jiao, Teng Zhang, Qingqing Liu, Jinwen Ye, Feng Yuan, Baoxia Cui   +6 more
openalex   +1 more source

Fat Mass and Obesity‐Associated Protein Contributes to Tumorigenesis and Drug Resistance of Diffuse Large B‐Cell Lymphoma by Suppressing N6‐Methyladenosine Methylation of Myc

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu, Jin‐Hao Chen, Yan‐Fang Wang, Xiao Wu, Hui‐Yun Ni, Qiu‐Rong Zhang   +5 more
wiley   +1 more source

YBX1 is Regulated by m6A Involved eIF3a Recognition and Promotes Liver Steatosis by Inhibiting PPARαTranslation

, 2023
Jingsu Yu, Liang Huang, Xiangling Li, Xinyu Qi, Kang Liu, Yu Lin, Songtao Su, Zeqiang Ma, Tengda Huang, Yixing Li, Batbold Batsaikhan, Turtushikh Damba, Yunxiao Liang, Jianrong Yang, Lei Zhou   +14 more
openalex   +1 more source

Mettl3-Mediated m6A Methylation Controls Pancreatic Bipotent Progenitor Fate and Islet Formation [PDF]

, 2023
Jiajun Sun, Yanqiu Wang, Hui Fu, Fuyun Kang, Jiaxi Song, Min Xu, Guang Ning, Jian Wang, Weiqing Wang, Qidi Wang   +9 more
openalex   +1 more source

Molecular Mechanism of the IRF1/NFE2L1‐DT/ALKBH5/Cx43 Axis in Radiation‐Induced Injury in Vascular Endothelial Cells Through Pyroptosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Radiotherapy effectively eradicates tumor cells but can also trigger pyroptotic damage in vascular endothelial cells. This study investigates the role of interferon regulatory factor 1 (IRF1) in radiation‐induced endothelial injury, aiming to provide mechanistic insights for optimizing radiotherapy.
Chen Li, Jia‐Wen Yang, Yong‐Rui Jia, Jie Zhang, Qiao Gou   +4 more
wiley   +1 more source

m6A-mediated translation regulation [PDF]

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2019
openaire   +2 more sources

Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury

Med Research, EarlyView.
ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang, Yuying Mo, Zhishan Ling, Yuting Zeng, Qi Zhang, Shuqi Zheng, Shuyang Wen, Yupeng Xiao, Siying Long, Tingting Yang, Qianru Li, Wenjie Shi, Guozhi Huang, Qing Zeng   +13 more
wiley   +1 more source

Enhancing m6A modification of lncRNA through METTL3 and RBM15 to promote malignant progression in bladder cancer [PDF]

Yapeng Huang, Yifan Lv, Baotong Yang, Shike Zhang, Bizhi Liu, Chengcheng Zhang, Wenyu Hu, Lujing Jiang, Cong Chen, Ding Ji, Chang Xiong, Yaoming Liang, Mingrui Liu, Xiaoling Ying, Weidong Ji   +14 more
openalex   +1 more source

Fuzzy Data Mining and Bioinformatics Analysis in Methylation Analysis of M6A Gene Promoter Region in Esophageal Cancer [PDF]

, 2022
Shuoming Wu, Xiangbao Yang, Xie Qiu, Yinpeng Pan   +3 more
openalex   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source