Results 191 to 200 of about 36,922 (295)

Understanding exosomes in regenerative dentistry

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad   +2 more
wiley   +1 more source

Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley   +1 more source

Deciphering the Functional Mechanisms of eIF3f in Tumors and Exploring Targeted Therapies

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Eukaryotic translation initiation factor 3 subunit F (eIF3f) is a critical component of the eIF3 complex and plays a pivotal role in diverse biological processes, including cell proliferation, apoptosis, adhesion, and transcriptional regulation.
Yujinpeng Hao   +3 more
wiley   +1 more source

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

open access: yesInternational Journal of Cancer, Volume 159, Issue 2, Page 302-319, 15 July 2026.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon   +5 more
wiley   +1 more source

Development of Quorum Sensing Modulators of Streptococcus constellatus

open access: yesChemBioChem, Volume 27, Issue 13, 14 July 2026.
Using a rational design approach, novel Streptococcus constellatus competence stimulating peptide (CSP) analogs with enhanced potencies were developed. These newly identified CSP analogs provide a rational framework for the development of CSP‐based quorum sensing modulators with translational potential in attenuating virulence processes in this ...
Keely M. Rodriguez   +4 more
wiley   +1 more source

USP43‐mediated deubiquitination of SLC7A11 protects against LPS‐induced acute lung injury by inhibiting ferroptosis

open access: yesClinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Ubiquitin‐specific protease 43 (USP43) in up‐regulated during lipopolysaccharide (LPS)‐induced acute lung injury (ALI). USP43 interacts and inhibits the degradation of solute carrier family 7 member 11 (SLC7A11) by removing the K48‐linked ubiquitination of it, thereby suppressing ferroptosis.
Li Zhang   +7 more
wiley   +1 more source

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