Genome-Wide Characterization and Expression Profiling of Putative m<sup>6</sup>A Methylation Regulatory Proteins (Writers and Erasers) in <i>Ginkgo biloba</i>. [PDF]
Ma Y +7 more
europepmc +1 more source
Understanding exosomes in regenerative dentistry
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad +2 more
wiley +1 more source
Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities
Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley +1 more source
<i>Maackia amurensis</i> seed lectin inhibits oral squamous cell carcinoma tumorigenesis by suppressing N6-methyladenosine modification-mediated SRY-box transcription factor 2 expression. [PDF]
Du Y +6 more
europepmc +1 more source
Deciphering the Functional Mechanisms of eIF3f in Tumors and Exploring Targeted Therapies
ABSTRACT Eukaryotic translation initiation factor 3 subunit F (eIF3f) is a critical component of the eIF3 complex and plays a pivotal role in diverse biological processes, including cell proliferation, apoptosis, adhesion, and transcriptional regulation.
Yujinpeng Hao +3 more
wiley +1 more source
Size-Dependent Layered Double Hydroxide Nanoparticles Promote Osteogenesis and Bone Regeneration via METTL3-Dependent N6-Methyladenosine Modification of Runx2 mRNA. [PDF]
Zhu Y +7 more
europepmc +1 more source
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon +5 more
wiley +1 more source
Development of Quorum Sensing Modulators of Streptococcus constellatus
Using a rational design approach, novel Streptococcus constellatus competence stimulating peptide (CSP) analogs with enhanced potencies were developed. These newly identified CSP analogs provide a rational framework for the development of CSP‐based quorum sensing modulators with translational potential in attenuating virulence processes in this ...
Keely M. Rodriguez +4 more
wiley +1 more source
m<sup>6</sup>A modification in skeletal system diseases (Review). [PDF]
Xie X, Li C, Zheng H, Gan G, Gao X.
europepmc +1 more source
Ubiquitin‐specific protease 43 (USP43) in up‐regulated during lipopolysaccharide (LPS)‐induced acute lung injury (ALI). USP43 interacts and inhibits the degradation of solute carrier family 7 member 11 (SLC7A11) by removing the K48‐linked ubiquitination of it, thereby suppressing ferroptosis.
Li Zhang +7 more
wiley +1 more source

