Results 201 to 210 of about 36,922 (295)

Ubiquitination and N⁶-methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review). [PDF]

Oncol Lett
Li H, Lu X.
europepmc   +1 more source

m6A-Methylated NUTM2B-AS1 Promotes Hepatocellular Carcinoma Stemness Feature via Epigenetically Activating BMPR1A Transcription

Wenchuan Li,1,2,* Min Zeng,3,* Yuanjia Ning,3,* Rongzhou Lu,3 Yunyu Wei,3 Zuoming Xu,2 Huamei Wei,1,4 Jian Pu1,2 1Guangxi Clinical Medical Research Center for Hepatobiliary Diseases, Baise, People’s Republic of China; 2Department of ...
Li W, Zeng M, Ning Y, Pu J, Wei H, Wei Y, Xu Z, Lu R   +7 more
core  

Tumour‐macrophage crosstalk initiated by NFIC/METTL3 negative feedback loop via exosomal miR‐194‐5p promotes NSCLC progression

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
NFIC/METTL3 negative feedback loop in NSCLC cells suppresses exosomal miR‐194‐5p via m6A methylation; reduced miR‐194‐5p deepresses ZNF106 in macrophages, promoting M2 polarization and IL‐6 secretion; Macrophage‐derived IL‐6 activates JAK2/STAT3 in NSCLC cells to upregulate METTL3, forming a positive feedback loop.
Shu Fang, Mingyue Hao, Han Meng, Yuhang Jiang, Qiwen Li, Jiao Liang, Xiaolu He, Yi Hu, Linling Zhou, Qianrun Wang, Qiyuan Zhuo, Ji Wu, Kesong Shi   +12 more
wiley   +1 more source

RBM45 Preferential Binding to m⁶A: Simulations Suggest Synergy of RRM3 and Other Domains. [PDF]

J Phys Chem B
Park R, Contreras LM, Tamamis P.
europepmc   +1 more source

PKMYT1 in Cancer: Beyond Cell Cycle Checkpoints to Context‐Dependent Therapeutic Vulnerability

Genes, Chromosomes and Cancer, Volume 65, Issue 7, July 2026.
ABSTRACT PKMYT1 has emerged as a promising therapeutic target distinguished by its tumor‐selective expression and essential role in replication stress management. Unlike WEE1, PKMYT1 is dispensable in normal cell cycles but critical for cancer cells coping with DNA damage, establishing a broad therapeutic window.
Lingxi Li, Binfan He, Mengmeng Hao, Ye Liu, Shunxin Song, Rongzhang He   +5 more
wiley   +1 more source

Epitranscriptomic regulation of endothelial plasticity under hemodynamic forces: insights from the KLF2/4-METTL3-H19 pathway. [PDF]

Front Genet
Huang J, Yang Y.
europepmc   +1 more source

m6A partial differential [PDF]

Nature Chemical Biology, 2015
openaire   +1 more source

Recent Advances in the Mutual Regulation of m6A Modification and Non-Coding RNAs in Atherosclerosis

Yanlu Wang, Sisi Ling, Hao Feng, Junkai Hua, Zhiyu Han, Renjie Chai Department of Cardiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, 510260, People’s Republic of ChinaCorrespondence: Renjie Chai ...
Ling S, Hua J, Chai R, Feng H, Han Z, Wang Y   +5 more
core  

Immune, molecular and genetic profiles of gastric signet ring cell carcinoma: Recent progress and future challenges

International Journal of Cancer, Volume 159, Issue 1, Page 11-29, 1 July 2026.
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang, Shuai Zhou, Xiongchao Fang, Xianli He, Gang Wang, Nan Wang   +5 more
wiley   +1 more source

Resolving METTL5 Specificity: Direct RNA Sequencing Reveals No Compelling Evidence for METTL5 mediated mRNA m6A Methylation in mESCs. [PDF]

MicroPubl Biol
Le Cam S, Valenta M, Schneider R.
europepmc   +1 more source