Yuan Tian,1 Kang Tao,1 Shifei Li,1 Xiaoqiang Chen,2 Rupeng Wang,3 Mingwang Zhang,1 Zhifang Zhai1 1Department of Dermatology, The First Affiliated Hospital, Army Medical University, Chongqing, People’s Republic of China; 2Department of Dermatology ...
Tao K +6 more
core
ABSTRACT Oncogenic condensates act as biophysical sanctuaries that stabilize malignant survival programs. However, a universal regulator capable of orchestrating the integrated biophysical axes governing cellular phase behavior has remained elusive.
Doris Loh +3 more
wiley +1 more source
Electroacupuncture Ameliorates Premature Ovarian Insufficiency by Inhibiting METTL3-Mediated m6A Methylation of Beclin 1 mRNA in Granulosa Cells. [PDF]
Ling L +9 more
europepmc +1 more source
ABSTRACT N6‐methyladenosine (m6A) is the most prevalent methylation modification present in mRNAs, which has been confirmed to participate in many developmental and biological processes. However, the biological function and specific regulatory mechanism of m6A modification in relation to salt tolerance of potato remain obscure.
Xuanming Dong +6 more
wiley +1 more source
METTL3-Mediated m6A Modification of lncRNA-0949 Drives Microglial Inflammation in an vitro Model of Sepsis-Associated Encephalopathy. [PDF]
Zeng X +4 more
europepmc +1 more source
Salt Stress Adaptations in Soybean Involve Alterations in Pre‐mRNA Processing
ABSTRACT Salt stress can seriously affect plant survival. To adapt to salt stress, plants can alter gene expressions and/or pre‐mRNA processing patterns, or both. Previous studies could not comprehensively profile stress‐responsive pre‐mRNA processing patterns due to limitations in traditional sequencing technologies.
Shoudong Zhang +9 more
wiley +1 more source
FTO-mediated m<sup>6</sup>A demethylation of BCL6 promotes gastric cancer progression by suppressing ferroptosis. [PDF]
Wang Y, Fan F, Zhan Z, Yu C, Chen S.
europepmc +1 more source
Engineering Bisubstrates to Target m6Am RNA Methyltransferases: Synthesis and Computational Studies
Use of the convertible nucleoside approach to synthesize m6Am RNA methyltransferase bisubstrates. This methodology allows for the introduction of modifications on the SAM analog moiety and the RNA substrate part, including the introduction of a cap analog by click chemistry.
Yoann Colas +3 more
wiley +1 more source
Landscape of N<sup>6</sup>-methyladenosine (m<sup>6</sup>A) methylation in porcine cells identifies candidate genes associated with porcine epidemic diarrhea virus infection. [PDF]
Dong X, Zhang Y, Wang Y, Wang C, Zhou A.
europepmc +1 more source
Direct RNA sequencing of primary human valvular interstitial cells (VICs) from non‐calcified control and fibro‐calcific aortic stenosis (AS) valves reveals disease‐associated remodeling of m6A RNA methylation. AS‐derived VICs show an overall increase in detected m6A sites, together with transcript‐specific hyper‐ and hypo‐methylation patterns ...
Vincenza Valerio +6 more
wiley +1 more source

