Results 221 to 230 of about 36,922 (295)

Identification of m6A-Related Biomarkers in Systemic Lupus Erythematosus: A Bioinformation-Based Analysis

open access: yes
Yuan Tian,1 Kang Tao,1 Shifei Li,1 Xiaoqiang Chen,2 Rupeng Wang,3 Mingwang Zhang,1 Zhifang Zhai1 1Department of Dermatology, The First Affiliated Hospital, Army Medical University, Chongqing, People’s Republic of China; 2Department of Dermatology ...
Tao K   +6 more
core  

Multiaxial Biophysical Control of Oncogenic Phase Separation by Indoleamines: A Proof‐of‐Concept Synthesis of Landscape‐Level Regulation

open access: yesJournal of Pineal Research, Volume 78, Issue 4, July 2026.
ABSTRACT Oncogenic condensates act as biophysical sanctuaries that stabilize malignant survival programs. However, a universal regulator capable of orchestrating the integrated biophysical axes governing cellular phase behavior has remained elusive.
Doris Loh   +3 more
wiley   +1 more source

StALKBH10B‐Mediated RNA m6A Modification Inhibits Potato Salt Tolerance by Targeting Flavonoids and ABA Signalling Pathways

open access: yesPlant Biotechnology Journal, Volume 24, Issue 7, Page 4435-4453, July 2026.
ABSTRACT N6‐methyladenosine (m6A) is the most prevalent methylation modification present in mRNAs, which has been confirmed to participate in many developmental and biological processes. However, the biological function and specific regulatory mechanism of m6A modification in relation to salt tolerance of potato remain obscure.
Xuanming Dong   +6 more
wiley   +1 more source

Salt Stress Adaptations in Soybean Involve Alterations in Pre‐mRNA Processing

open access: yesPlant, Cell &Environment, Volume 49, Issue 7, Page 4000-4014, July 2026.
ABSTRACT Salt stress can seriously affect plant survival. To adapt to salt stress, plants can alter gene expressions and/or pre‐mRNA processing patterns, or both. Previous studies could not comprehensively profile stress‐responsive pre‐mRNA processing patterns due to limitations in traditional sequencing technologies.
Shoudong Zhang   +9 more
wiley   +1 more source

Engineering Bisubstrates to Target m6Am RNA Methyltransferases: Synthesis and Computational Studies

open access: yesChemistry – A European Journal, Volume 32, Issue 24, 23 June 2026.
Use of the convertible nucleoside approach to synthesize m6Am RNA methyltransferase bisubstrates. This methodology allows for the introduction of modifications on the SAM analog moiety and the RNA substrate part, including the introduction of a cap analog by click chemistry.
Yoann Colas   +3 more
wiley   +1 more source

Disease‐Associated Remodeling of m6A RNA Methylation in Human Interstitial Cells From Fibro‐Calcific Aortic Valves

open access: yesThe FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Direct RNA sequencing of primary human valvular interstitial cells (VICs) from non‐calcified control and fibro‐calcific aortic stenosis (AS) valves reveals disease‐associated remodeling of m6A RNA methylation. AS‐derived VICs show an overall increase in detected m6A sites, together with transcript‐specific hyper‐ and hypo‐methylation patterns ...
Vincenza Valerio   +6 more
wiley   +1 more source

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