Results 221 to 230 of about 63,662 (384)

FB23‐2 and Cisplatin Synergize to Inhibit Head and Neck Squamous Cell Carcinoma by Targeting the XPF/ERCC1 Complex

open access: yesCancer Science, EarlyView.
FB23‐2 potentiates cisplatin's antitumor efficacy in head and neck squamous cell carcinoma by disrupting XPF/ERCC1 complex assembly and nuclear translocation, thereby suppressing DNA damage repair machinery and amplifying platinum‐induced tumor cell death.
Yaoqi Jiang   +7 more
wiley   +1 more source

m6A partial differential [PDF]

open access: yesNature Chemical Biology, 2015
openaire   +1 more source

Homoharringtonine Promotes FTO Degradation to Suppress LILRB4‐Mediated Immune Evasion in Acute Monocytic Leukaemia

open access: yesCell Proliferation, EarlyView.
Homoharringtonine (HHT) suppresses immune evasion in acute monocytic leukaemia (AML‐M5) by attenuating the FTO/m6A/LILRB4 axis, thereby enhancing CD8+ T cell cytotoxicity. ABSTRACT Acute monocytic leukaemia, a subtype of acute myeloid leukaemia (AML), is a highly aggressive malignancy characterised by a poor prognosis, primarily due to the ability of ...
Fangfang Huang   +18 more
wiley   +1 more source

RNA stability controlled by m6A methylation contributes to X-to-autosome dosage compensation in mammals [PDF]

open access: hybrid, 2023
Cornelia Rücklé   +16 more
openalex   +1 more source

Non‐Coding RNAs in Breast Cancer Radioresistance: Mechanisms, Functional Roles and Translational Potentials

open access: yesCell Proliferation, EarlyView.
Non‐coding RNAs (ncRNAs) regulate breast cancer radioresistance via cell cycle, DNA repair and tumour microenvironment pathways. Targeting ncRNAs (e.g., HOTAIR and miR‐155) with RNA‐based therapies (ASOs and CRISPR) shows promise but faces delivery challenges.
Xiaohui Zhao   +8 more
wiley   +1 more source

Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis

open access: green, 2022
Wenqi Xu   +13 more
openalex   +2 more sources

The m6A methylation regulates gonadal sex differentiation in chicken embryo [PDF]

open access: gold, 2022
Jianbo Li   +7 more
openalex   +1 more source

Japanese EFL Learners’ Perspectives on the Inclusion of Diverse English Accents in Audio Recordings for Textbooks and Listening Tests

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT The use of English accents beyond standard American and British varieties has been increasingly advocated in English language education, particularly in listening instruction and assessment. However, little is known about learners’ perspectives on diverse accents in terms of their use in different types of listening materials.
Ryuichi Suzuki   +2 more
wiley   +1 more source

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