Results 251 to 260 of about 63,662 (384)

The Regulatory Role of m⁶A Modification in the Function and Signaling Pathways of Animal Stem Cells. [PDF]

Cells
Yang X, Xu Y, Zhu S, Wang M, Cao H, Lu L.   +5 more
europepmc   +1 more source

Metabolic reprogramming of efferocytosis in the tumour microenvironment: From apoptotic‐cell clearance to therapeutic targeting

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
This review systematically deconstructs the pathological efferocytic—metabolic axis in tumours, framing it as a three‐stage, self‐reinforcing cycle: from metabolite‐driven macrophage recruitment, through hijacked surface recognition, to post‐phagocytic metabolic reprogramming that locks in immunosuppression.
Qianlu Yang, Jie Yan, Qianxi Yang
wiley   +1 more source

m6A-Modified Nucleotide Bases Improve Translation of In Vitro-Transcribed Chimeric Antigen Receptor (CAR) mRNA in T Cells. [PDF]

Int J Mol Sci
Lao N, Li S, Ainciburu M, Barron N.
europepmc   +1 more source

FTO aggravates podocyte injury and diabetic nephropathy progression via m6A-dependent stabilization of ACC1 mRNA and promoting fatty acid metabolism

Kaili Chang, Fu‐Yuan Hong, Hong Liu, Yi Fang, Hongyu Wang, Nana Song, Yichun Ning, Zhihui Lu, Jin Shi, Yan Dai, Xiaoqiang Ding   +10 more
openalex   +1 more source

Targeting m6A modification inhibits herpes virus 1 infection

, 2021
Zhuoying Feng, Fanghang Zhou, Miaomiao Tan, Tingting Wang, Ying Chen, Wenwen Xu, Bin Li, Xin Wang, Xin Deng, Ming‐Liang He   +9 more
openalex   +1 more source

The ZNF148‐ZEB1‐AS1‐IGF2BP2‐NOD2 Axis Drives Microglial Antipneumococcal Immunity in Bacterial Meningitis

Glia, Volume 74, Issue 2, February 2026.
ZNF148 upregulates ZEB1‐AS1, which scaffolds IGF2BP2 to stabilize NOD2 mRNA, enhancing microglial anti‐pneumococcal immunity via cytokine production and bacterial clearance in bacterial meningitis. ABSTRACT Streptococcus pneumoniae (Spn) meningitis remains a lethal central nervous system (CNS) infection with limited therapies. This study identifies the
Xiufu Hu, Fang Jiang, Xinjie Liu, Ling Li, Ruimei Hu, Meng Dong, Aihua Cao   +6 more
wiley   +1 more source

M6AREG 2.0: the landscape of m6A-centered crosstalk with diverse epigenetic regulation. [PDF]

Nucleic Acids Res
Yang M, Zhou Y, Yang L, Yu X, Ge Y, Zhou X, Li X, Chen F, Zhang Y, Dai H, Liu S, Zhu F.   +11 more
europepmc   +1 more source

The m6A epitranscriptome opens a new charter in immune system logic [PDF]

, 2020
Zhonghua Ma, Xiangyu Gao, You Shuai, Xiaofang Xing, Jiafu Ji   +4 more
openalex   +1 more source

Loss of METTL3 m6A methyltransferase results in short‐term progression and poor treatment outcome of bladder cancer patients

International Journal of Cancer, Volume 158, Issue 3, Page 763-774, 1 February 2026.
What's new? Bladder cancer exhibits a highly heterogeneous molecular landscape and treatment response. The dysregulation of RNA modifications such as m6A has been involved in cancer initiation and progression. This study comprehensively analyzed the expression of the main catalytic component of the m6A methylation machinery in bladder tumors across one
Katerina‐Marina Pilala, Stella Koroneou, Maria‐Alexandra Papadimitriou, Konstantina Panoutsopoulou, Konstantinos Soureas, Georgios‐Christos Giagkos, Panagiotis Levis, Dimitrios Linardoutsos, Konstantinos Stravodimos, Margaritis Avgeris, Andreas Scorilas   +10 more
wiley   +1 more source

METTL14 Promotes Lipid Synthesis in Dairy Goat Mammary Epithelial Cells by Targeting <i>CEBPB</i> via m6A-YTHDF1/3-Dependent Manner. [PDF]

Animals (Basel)
Jiao H, Zhu L, Tang X, Gong P, Wang W, Liu B, Luo J.   +6 more
europepmc   +1 more source