Results 21 to 30 of about 58,783 (322)
Eye Movements Actively Reinstate Spatiotemporal Mnemonic Content
Vision, 2019 Eye movements support memory encoding by binding distinct elements of the visual world into coherent representations. However, the role of eye movements in memory retrieval is less clear.
Jordana S. Wynn +2 more
doaj +1 more source
Exon architecture controls mRNA m6A suppression and gene expression
Science, 2023 N6-methyladenosine (m6A) is the most abundant messenger RNA (mRNA) modification and plays crucial roles in diverse physiological processes. Using a massively parallel assay for m6A (MPm6A), we discover that m6A specificity is globally regulated by ...
P. He +13 more
semanticscholar +1 more source
The role of m6A methylation in therapy resistance in cancer
Molecular Cancer, 2023 Cancer therapy resistance is the main cause of cancer treatment failure. The mechanism of therapy resistance is a hot topic in epigenetics. As one of the most common RNA modifications, N6-methyladenosine (m6A) is involved in various processes of RNA ...
Hengzhao Zhuang +7 more
semanticscholar +1 more source
METTL3 regulates WTAP protein homeostasis [PDF]
, 2018 The Wilms tumor 1 (WT1)-associated protein (WTAP) is upregulated in many tumors, including, acute myeloid leukemia (AML), where it plays an oncogenic role by interacting with different proteins involved in RNA processing and cell proliferation.
Capuano, Ernestina +8 more
core +2 more sources
m6A-dependent regulation of messenger RNA stability
Nature, 2013 N6-methyladenosine (m6A) is the most prevalent internal (non-cap) modification present in the messenger RNA of all higher eukaryotes. Although essential to cell viability and development, the exact role of m6A modification remains to be determined.
Xiao Wang +12 more
semanticscholar +1 more source
Frontiers in Bioscience-Landmark, 2022 N6-methyladenosine (m6A) methylation/modification plays a critical role in various biological processes through post-transcriptional ribonucleic acid (RNA) modification, which involves RNA processing, nuclear export, translation and decay.
Xiaohua Li +8 more
doaj +1 more source
Modulation of internuclear communication in multinuclear Ruthenium(II) polypyridyl complexes [PDF]
, 2003 The syntheses and characterisation of a series of mononuclear and dinuclear ruthenium polypyridyl complexes based on the bridging ligands 1,3-bis-[5-(2-pyridyl)-1H-1,2,4-triazol-3-yl]benzene, 1,4-bis-[5-(2-pyridyl)-1H-1,2,4-triazol-3-yl]benzene, 2,5-bis-[
Adrian Guckian +4 more
core +2 more sources
Functional organization of box C/D RNA-guided RNA methyltransferase [PDF]
, 2020 Box C/D RNA protein complexes (RNPs) catalyze site-specific 2'-O-methylation of RNA with specificity determined by guide RNAs. In eukaryotic C/D RNP, the paralogous Nop58 and Nop56 proteins specifically associate with terminal C/D and internal C'/D ...
Huang, Lin +4 more
core +2 more sources
Heliyon, 2023 Cholangiocarcinoma (CCA) is a serious malignancy originating from the bile ducts and the second most common primary liver cancer. Long non-coding RNA (lncRNA) is a functional lncRNA that plays an important role in human cancers. However, the role and underlying mechanisms of CTBP1-AS2 in CCA remain unknown.In this study, we investigated the functional ...
Zhe Jin, Yahui Liu
openaire +3 more sources
Developmental Cognitive Neuroscience, 2019 Variability of neural signaling is an important index of healthy brain functioning, as is signal complexity, which relates to information processing capacity. Alterations in variability and complexity may underlie certain brain dysfunctions.
Amanda K. Easson, Anthony R. McIntosh
doaj +1 more source