Results 171 to 180 of about 2,779 (193)
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Ribonucleic acids of Machupo and Lassa viruses
Archives of Virology, 1984Sucrose gradient velocity centrifugation, polyacrylamide gel electrophoresis and RNA-RNA hybridization were used to characterize Lassa and Machupo virion RNAs as well as virus-specific RNAs from cells infected with Pichinde and Machupo viruses. Five RNA species: 30-31S, 28S, 22-24S, 18S and 4-6S have been detected in Lassa, Machupo, and Pichinde virion
I S, Lukashevich +4 more
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Immune Tolerance in Calomys callosus infected with Machupo Virus
Nature, 1969MACHUPO virus, the aetiological agent of Bolivian haemorrhagic fever, is an ether-sensitive RNA virus immunologically classified as a member of the Tacaribe group of “arboviruses”1–3. Repeated isolation of this virus from the cricetine rodent Calomys callosus4, the demonstration of chronic virus infection with persistent viruria in this animal5, and ...
G, Justines, K M, Johnson
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Isolation of Machupo Virus from Wild Rodent Calomys callosus
American Journal of Tropical Medicine and Hygiene, 1966Summary Nine virus strains were recovered from a small group of tissues from the wild rodent Calomys callosus captured in the area of San Joaquin, Bolivia, in 1963. Each virus was successfully reisolated and shown to be serologically related to Machupo virus, the etiologic agent of Bolivian Hemorrhagic Fever.
K M, Johnson +4 more
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The American Journal of Tropical Medicine and Hygiene, 1965
Comment and Summary The infant hamster appears to be the most sensitive host system thus far devised for detection of naturally occurring strains of Machupo virus. Infected brains also serve as a convenient source of CF antigens which can be employed for provisional grouping of hamster pathogenic isolates.
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Comment and Summary The infant hamster appears to be the most sensitive host system thus far devised for detection of naturally occurring strains of Machupo virus. Infected brains also serve as a convenient source of CF antigens which can be employed for provisional grouping of hamster pathogenic isolates.
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A Multi-epitope Vaccine Candidate Against Bolivian Hemorrhagic fever Caused by Machupo Virus
Applied Biochemistry and Biotechnology, 2023Bolivian hemorrhagic fever (BHF) caused by Machupo virus (MACV) is a New World arenavirus having a reported mortality rate of 25-35%. The BHF starts with fever, followed by headache, and nausea which rapidly progresses to severe hemorrhagic phase within 7 days of disease onset.
Zeeshan Ali +9 more
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Immunologic Studies of Tacaribe, Junín and Machupo Viruses
The American Journal of Tropical Medicine and Hygiene, 1965Previous publications describe preparation of Tacaribe, Junin and Machupo virus antigens and their reciprocal cross-reactions in the complement fixation (CF) test (Mettler 1961, Wiebenga 1964, Johnson 1965). Production of plaques after viral infection of cell cultures (Tauraso 1964) and serum neutralization of plaques by homotypic antiserum (Johnson ...
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In vitro translation of mRNA species from cells infected with Machupo virus
Archives of Virology, 1987RNA from Machupo virus infected cells was centrifuged in a linear sucrose gradient and RNAs from gradient fractions were tested separately for template activity in a cell-free protein synthesizing system from rabbit reticulocytes. Fraction 15-16 S programmed the synthesis of protein that migrated in SDS-polyacrylamide gel like the nucleocapsid protein ...
I S, Lukashevich +3 more
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Some Characteristics of Machupo Virus, Causative Agent of Bolivian Hemorrhagic Fever
American Journal of Tropical Medicine and Hygiene, 1967Summary Certain properties of Machupo virus are reported. These include presence of RNA, pH stability in the range of 6.0 to 9.0, rapid thermal inactivation at temperatures of 25°C and higher, and more effective stabilization of infectivity titers after prolonged storage (1 year) at -70°C in media containing protein supplements.
P A, Webb +3 more
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The History of Machupo Virus in Bolivia: Arenavirus Hemorrhagic Fever
1998Yambuku is what the Africans called the Ebola virus that struck hundreds of victims in Sub-Sahara Africa in 1993 and received so much notoriety in the American news media. What most people do not know is that an outbreak of a "sister" virus to Ebola occurred in a small community in the Amazon Basin in Bolivia about one year later. Similar to its deadly
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Machupo Virus and Bolivian Hemorrhagic Fever: Epidemiology, Pathogenesis, and Control Strategies
Journal of Public Health, Policy, and SocietyMachupo virus, a member of the Mammarenavirus genus within the Arenaviridae family, is the etiological agent of Bolivian Hemorrhagic Fever (BHF). This enveloped virus possesses a bi-segmented, single-stranded ambisense RNA genome. The small (S) segment encodes the glycoprotein precursor (GPC) and nucleoprotein (NP), while the large (L) segment encodes ...
I. H. Iheukwumere +5 more
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