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Design and Implementation of a One Health Framework for Evaluating the Transmission Potential of Pathogens of Public Health Interest for Surveillance Studies. [PDF]
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Proceedings from the Fourth Mesoamerican Symposium "Dr. Roberto Navarro López" on Emerging Zoonotic Disease and Arboviruses: Commenting Insights and Research Findings. [PDF]
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Chronic Infection of Rodents by Machupo Virus
Science, 1965Machupo virus, the etiologic agent of human hemorrhagic fever in Bolivia, induced chronic asymptomatic infection in laboratory hamsters and colonized individuals of the peridomestic, wild, South American rodent, Calomys callosus . Viruria was detected for more than 500 and 150 days, respectively, in the two species.
K M, Johnson +3 more
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Immune Tolerance in Calomys callosus infected with Machupo Virus
Nature, 1969MACHUPO virus, the aetiological agent of Bolivian haemorrhagic fever, is an ether-sensitive RNA virus immunologically classified as a member of the Tacaribe group of “arboviruses”1–3. Repeated isolation of this virus from the cricetine rodent Calomys callosus4, the demonstration of chronic virus infection with persistent viruria in this animal5, and ...
G, Justines, K M, Johnson
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Epidemiology of Machupo Virus Infection
The American Journal of Tropical Medicine and Hygiene, 1965Summary The localities in Bolivia from which cases of hemorrhagic fever have been reported are farming communities with characteristic ecological features. The rodent, Calomys callosus, is an important reservoir host of the Machupo virus. An experimental program of disease control was successfully carried out in San Joaquin, Beni, Bolivia.
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Isolation of Machupo Virus from Wild Rodent Calomys callosus
The American Journal of Tropical Medicine and Hygiene, 1966Summary Nine virus strains were recovered from a small group of tissues from the wild rodent Calomys callosus captured in the area of San Joaquin, Bolivia, in 1963. Each virus was successfully reisolated and shown to be serologically related to Machupo virus, the etiologic agent of Bolivian Hemorrhagic Fever.
K M, Johnson +4 more
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Machupo virus polypeptides: Identification by immunoprecipitation
Archives of Virology, 1985The most abundant protein in purified Machupo virions (Corvallo strain) labelled with 14C-Protein hydrolysate is a 64 K polypeptide which is associated with virion RNAs. Another structural polypeptide, 37 K, solubilized by nonionic detergent seems to be a major surface glycoprotein.
I S, Lukashevich, N N, Lemeshko
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A Multi-epitope Vaccine Candidate Against Bolivian Hemorrhagic fever Caused by Machupo Virus
Applied Biochemistry and Biotechnology, 2023Bolivian hemorrhagic fever (BHF) caused by Machupo virus (MACV) is a New World arenavirus having a reported mortality rate of 25-35%. The BHF starts with fever, followed by headache, and nausea which rapidly progresses to severe hemorrhagic phase within 7 days of disease onset.
Zeeshan Ali +9 more
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