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Properties of Machupo Virus

The American Journal of Tropical Medicine and Hygiene, 1965
Comment and Summary The infant hamster appears to be the most sensitive host system thus far devised for detection of naturally occurring strains of Machupo virus. Infected brains also serve as a convenient source of CF antigens which can be employed for provisional grouping of hamster pathogenic isolates.
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Some Characteristics of Machupo Virus, Causative Agent of Bolivian Hemorrhagic Fever

The American Journal of Tropical Medicine and Hygiene, 1967
Summary Certain properties of Machupo virus are reported. These include presence of RNA, pH stability in the range of 6.0 to 9.0, rapid thermal inactivation at temperatures of 25°C and higher, and more effective stabilization of infectivity titers after prolonged storage (1 year) at -70°C in media containing protein supplements.
P A, Webb   +3 more
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In vitro translation of mRNA species from cells infected with Machupo virus

Archives of Virology, 1987
RNA from Machupo virus infected cells was centrifuged in a linear sucrose gradient and RNAs from gradient fractions were tested separately for template activity in a cell-free protein synthesizing system from rabbit reticulocytes. Fraction 15-16 S programmed the synthesis of protein that migrated in SDS-polyacrylamide gel like the nucleocapsid protein ...
I S, Lukashevich   +3 more
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The African Green Monkey as an Alternate Primate Host for Studying Machupo Virus Infection

The American Journal of Tropical Medicine and Hygiene, 1977
African green monkeys (Cercopithecus aethiops) are highly susceptible to Bolivian hemorrhagic fever (BHF). Six monkeys were inoculated with 1,000 plague-forming units of Machupo virus, the etiologic agent of BHF. They were observed and monitored for clinical signs, body temperature, viremia, hematologic changes, and virus neutralizing antibody.
F S, Wagner, G A, Eddy, O M, Brand
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The History of Machupo Virus in Bolivia: Arenavirus Hemorrhagic Fever

1998
Yambuku is what the Africans called the Ebola virus that struck hundreds of victims in Sub-Sahara Africa in 1993 and received so much notoriety in the American news media. What most people do not know is that an outbreak of a "sister" virus to Ebola occurred in a small community in the Amazon Basin in Bolivia about one year later. Similar to its deadly
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Machupo Virus and Bolivian Hemorrhagic Fever: Epidemiology, Pathogenesis, and Control Strategies

Journal of Public Health, Policy, and Society
Machupo virus, a member of the Mammarenavirus genus within the Arenaviridae family, is the etiological agent of Bolivian Hemorrhagic Fever (BHF). This enveloped virus possesses a bi-segmented, single-stranded ambisense RNA genome. The small (S) segment encodes the glycoprotein precursor (GPC) and nucleoprotein (NP), while the large (L) segment encodes ...
I. H. Iheukwumere   +5 more
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Cervical cancer prevention and control in women living with human immunodeficiency virus

Ca-A Cancer Journal for Clinicians, 2021
Philip Castle   +2 more
exaly  

Use of Oral Swabs for Detection of Machupo-Virus Infection in Rodents

The American Journal of Tropical Medicine and Hygiene, 1968
G, Justines, K M, Johnson
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A Multi-Epitope Vaccine Candidate Against Bolivian Hemorrhagic Fever Caused by Machupo Virus

SSRN Electronic Journal, 2022
Zeeshan Ali   +5 more
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