Developed has been the oligonucleotide liquid biochip based on xMAP technology, designed for the laboratory detection of particularly dangerous viral pathogens such as Ebola and Marburg filoviruses, and Machupo , Junin, and Lassa arenaviruses.
V. A. Ternovoy +5 more
doaj +1 more source
Аналіз повідомлення про інфекційне захворювання у Великобританії [PDF]
статті проаналізовано повідомлення про інфекційне захворювання у Великобританії — країні, що є членом Євросоюзу. Наведено перелік інфекційних захворювань та збудників інфекційних хвороб, про які слід повідомляти.
Савка, І.В. +2 more
core
Targeting of arenavirus RNA synthesis by a carboxamide-derivatized aromatic disulfide with virucidal activity. [PDF]
Several arenaviruses can cause severe hemorrhagic fever (HF) in humans, representing a public health threat in endemic areas of Africa and South America.
Damonte, Elsa Beatriz +4 more
core +2 more sources
Pathogenesis of Machupo virus infection in primates.
Experimental Machupo virus infection of rhesus and cynomolgus monkeys produced a severe illness consisting of an initial clinical phase and a later neurological phase. Cumulative mortality during the two phases was 80% and 95% respectively. Attempts to alter the pathogenesis with decomplementation or immunosuppression resulted in earlier deaths of the ...
G A, Eddy +3 more
openaire +1 more source
Morphological Comparison of Machupo with Lymphocytic Choriomeningitis Virus: Basis for a New Taxonomic Group [PDF]
Striking morphologic similarities between Machupo, Tacaribe, and lymphocytic choriomeningitis viruses were found by thin-section electron microscopy. It is proposed that these viruses be brought together into a single taxonomic group.
F A, Murphy +3 more
openaire +2 more sources
A One Health approach for South American hemorrhagic fevers
South American hemorrhagic fevers (SAHF) include five rodent-borne New World mammarenaviruses. These are Junin, Machupo, Chapare, Guanarito, and Sabia viruses.
Dr Rory Wilson, Dr Ariella Barry
doaj +1 more source
Human cytomegalovirus exploits interferon-induced transmembrane proteins to facilitate morphogenesis of the virion assembly compartment [PDF]
Recently, interferon-induced transmembrane proteins (IFITMs) have been identified to be key effector molecules in the host type I interferon defense system.
Li, Bin +9 more
core +2 more sources
The Curious Case of Arenavirus Entry, and Its Inhibition
Arenaviruses comprise a diverse family of enveloped negative-strand RNA viruses that are endemic to specific rodent hosts worldwide. Several arenaviruses cause severe hemorrhagic fevers in humans, including Junín and Machupo viruses in South America and ...
Joanne York, Jack H. Nunberg
doaj +1 more source
The introduction of bioterrorism in Malaysia: A legal approach [PDF]
The deliberate use of biological agents and the emergence of infectious diseases which can produce harm to human health and give effects to the public health and security are well recognised.A few years back, an attack of biological agents would be the ...
Abdul Rahim, Rohani, Abdullah, Nor Anita
core +1 more source
Small-Molecule Probes Targeting the Viral PPxY-Host Nedd4 Interface Block Egress of a Broad Range of RNA Viruses. [PDF]
Budding of filoviruses, arenaviruses, and rhabdoviruses is facilitated by subversion of host proteins, such as Nedd4 E3 ubiquitin ligase, by viral PPxY late (L) budding domains expressed within the matrix proteins of these RNA viruses.
Davis, Benjamin +11 more
core +2 more sources

