Results 81 to 90 of about 1,703 (147)

South American Hemorrhagic Fevers: A summary for clinicians

International Journal of Infectious Diseases, 2021
Objectives: This article is one of a series on acute, severe diseases of humans caused by emerging viruses for which there are no or limited licensed medical countermeasures.
Maria G. Frank, Adam Beitscher, Camille M. Webb, Vanessa Raabe, Adam Beitscher, Nahid Bhadelia, Theodore J. Cieslak, Richard T. Davey, Kerry Dierberg, Jared D. Evans, Maria G. Frank, Jonathan Grein, Mark G. Kortepeter, Colleen S. Kraft, Chris J. Kratochvil, Karen Martins, Susan McLellan, Aneesh K. Mehta, Vanessa Raabe, George Risi, Lauren Sauer, Erica S. Shenoy, Tim Uyeki   +22 more
doaj   +1 more source

Review of Mammarenavirus Biology and Replication

Frontiers in Microbiology, 2018
The family Arenaviridae is divided into three genera: Mammarenavirus, Reptarenavirus, and Hartmanivirus. The Mammarenaviruses contain viruses responsible for causing human hemorrhagic fever diseases including New World viruses Junin, Machupo, Guanarito ...
Steven J. Hallam, Takaaki Koma, Junki Maruyama, Slobodan Paessler   +3 more
doaj   +1 more source

DNAZYMES AS A METHOD FOR NIPAH HENIPAVIRUS DETECTION

International Journal of Infectious Diseases, 2023
Intro: Deoxyribozymes (Dz) are short synthetic DNA oligonucleotides that catalyze the cleavage of a phosphodiester bond between nucleotides in the presence of divalent metal ions.
A. Kirichenko, E. Bryushkova, A. Shabalina, V. Dedkov, A. Dolgova   +4 more
doaj   +1 more source

The Protein Kinase Receptor Modulates the Innate Immune Response against Tacaribe Virus

Viruses, 2021
The New World (NW) mammarenavirus group includes several zoonotic highly pathogenic viruses, such as Junin (JUNV) or Machupo (MACV). Contrary to the Old World mammarenavirus group, these viruses are not able to completely suppress the innate immune ...
Hector Moreno, Stefan Kunz
doaj   +1 more source

Affinity Maturated Transferrin Receptor Apical Domain Blocks Machupo Virus Glycoprotein Binding

Journal of Molecular Biology, 2023
Transferrin receptor 1 (TfR) delivers iron across cellular membranes by shuttling the ion carrier protein transferrin. This ability to deliver large protein ligands inside cells is taken advantage of by pathogens to infiltrate human cells. Notably, the receptor's outermost ectodomain, the apical domain, is used as a point of attachment for several ...
Sjöström, Dick J., Grill, Birgit, Ambrosetti, Elena, Veetil, Anuthariq Alikkam, Mohlin, Camilla, Teixeira, Ana I., Oberdofer, Gustav, Bjelic, Sinisa   +7 more
openaire   +3 more sources

Fiebres hemorrágicas por Arenavirus en Latinoamérica

Salud Uninorte, 2010
Las fiebres hemorrágicas virales producidas por Arenavirus incluyen a los virus endémicos en África (Lassa) y el virus de la coriomeningitis linfocítica (LCMV), de distribución mundial, y los Arenavirus del Nuevo Mundo o Complejo Tacaribe, que incluye a ...
Ella Soto, Salim Mattar
doaj  

Highly Effective xMAP Multiplex Assay for the Detection and Identification of Hemorrhagic Fever Agents, Including Ebola Virus

Проблемы особо опасных инфекций, 2015
Developed has been the oligonucleotide liquid biochip based on xMAP technology, designed for the laboratory detection of particularly dangerous viral pathogens such as Ebola and Marburg filoviruses, and Machupo , Junin, and Lassa arenaviruses.
V. A. Ternovoy, A. V. Sementsova, E. V. Chub, O. V. P’Yankov, V. B. Loktev, A. P. Agafonov   +5 more
doaj   +1 more source

Lassa fever. Part 1. Etiology, epidemiology and clinical manifestations

Инфекция и иммунитет, 2022
Lassa fever is a natural focal disease dangerous for humans. In the larger part of sub-Saharan West Africa 37.7 million people in 14 countries live in areas where living conditions are suitable for zoonotic transmission of the virus from secretions of ...
Elena I. Kazachinskaia, V. S. Aripov, A. V. Ivanova, A. M. Shestopalov   +3 more
doaj   +1 more source

Pathogenesis of Machupo virus infection in primates.

Bulletin of the World Health Organization, 1976
Experimental Machupo virus infection of rhesus and cynomolgus monkeys produced a severe illness consisting of an initial clinical phase and a later neurological phase. Cumulative mortality during the two phases was 80% and 95% respectively. Attempts to alter the pathogenesis with decomplementation or immunosuppression resulted in earlier deaths of the ...
G A, Eddy, S K, Scott, F S, Wagner, O M, Brand   +3 more
openaire   +1 more source

A One Health approach for South American hemorrhagic fevers

CABI One Health
South American hemorrhagic fevers (SAHF) include five rodent-borne New World mammarenaviruses. These are Junin, Machupo, Chapare, Guanarito, and Sabia viruses.
Dr Rory Wilson, Dr Ariella Barry
doaj   +1 more source