Results 71 to 80 of about 1,040,510 (176)
South American Hemorrhagic Fevers: A summary for clinicians
International Journal of Infectious Diseases, 2021 Objectives: This article is one of a series on acute, severe diseases of humans caused by emerging viruses for which there are no or limited licensed medical countermeasures.
Maria G. Frank +22 more
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Fiebres hemorrágicas por Arenavirus en Latinoamérica
Salud Uninorte, 2010 Las fiebres hemorrágicas virales producidas por Arenavirus incluyen a los virus endémicos en África (Lassa) y el virus de la coriomeningitis linfocítica (LCMV), de distribución mundial, y los Arenavirus del Nuevo Mundo o Complejo Tacaribe, que incluye a ...
Ella Soto, Salim Mattar
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Pathogenesis of Machupo virus infection in primates.
Bulletin of the World Health Organization, 1976 Experimental Machupo virus infection of rhesus and cynomolgus monkeys produced a severe illness consisting of an initial clinical phase and a later neurological phase. Cumulative mortality during the two phases was 80% and 95% respectively. Attempts to alter the pathogenesis with decomplementation or immunosuppression resulted in earlier deaths of the ...
G A, Eddy +3 more
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Проблемы особо опасных инфекций, 2015 Developed has been the oligonucleotide liquid biochip based on xMAP technology, designed for the laboratory detection of particularly dangerous viral pathogens such as Ebola and Marburg filoviruses, and Machupo , Junin, and Lassa arenaviruses.
V. A. Ternovoy +5 more
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A One Health approach for South American hemorrhagic fevers
CABI One HealthSouth American hemorrhagic fevers (SAHF) include five rodent-borne New World mammarenaviruses. These are Junin, Machupo, Chapare, Guanarito, and Sabia viruses.
Dr Rory Wilson, Dr Ariella Barry
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Experimental Biology and Medicine, 1969 SummaryMultiplication of Machupo virus, the etiological agent of Bolivian hemorrhagic fever, was studied in a variety of cell cultures. One line of African green monkey kidney cells (Vero) supported the multiplication of the virus to high titer, but developed no cytopathic effect.
J S, Rhim, B, Simizu, N H, Wiebenga
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[Sedimentation analysis of the virion RNA of Machupo virus].
Voprosy virusologii, 1983 Pichinde and Machupo viruses labeled with 3H-uridine were concentrated and purified by different methods. The buoyant density of the viruses was for Pichinde 1.14-1.15 g/cm3 (urographimeter), 1.19 g/cm3 (sucrose), 1.25 g/cm3 (cesium chloride), for Machupo virus 1.25 g/cm3 (cesium chloride).
I S, Lukashevich +4 more
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The Curious Case of Arenavirus Entry, and Its Inhibition
Viruses, 2012 Arenaviruses comprise a diverse family of enveloped negative-strand RNA viruses that are endemic to specific rodent hosts worldwide. Several arenaviruses cause severe hemorrhagic fevers in humans, including Junín and Machupo viruses in South America and ...
Joanne York, Jack H. Nunberg
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A review of emerging health threats from zoonotic New World mammarenaviruses
BMC MicrobiologyDespite repeated spillover transmission and their potential to cause significant morbidity and mortality in human hosts, the New World mammarenaviruses remain largely understudied.
Arianna Lendino +3 more
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[Effect of actinomycin D on the reproduction of the Machupo virus].
Voprosy virusologii, 1985 The effect of inhibitors of mRNA synthesis (actinomycin D and alpha-amanitin) and DNA replication (mitomycin C and ethidium bromide) on Machupo virus reproduction was studied. Actinomycin D (1.0-4.0 micrograms/ml) and alpha-amanitin (10.0 micrograms/ml) added immediately after adsorption reduced the infectious virus titre by 2 lg or more. Actinomycin D
I S, Lukashevich +2 more
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