Results 181 to 190 of about 9,528 (245)

Exploring the macrocyclic chemical space for heuristic drug design with deep learning models. [PDF]

open access: yesCommun Chem
Hu F   +14 more
europepmc   +1 more source

Defined Nylon Oligomers Enable Mechanistic Insight Into Enzymatic Polyamide Depolymerization

open access: yesChemSusChem, Volume 19, Issue 11, 15 June 2026.
The remarkable progress in enzymatic polyester depolymerization has demonstrated the potential of biocatalysis for sustainable polymer recycling. In contrast, enzymatic polyamide (PA) degradation remains poorly understood, largely due to the lack of defined and accessible model substrates.
Sukmanita Dewi   +3 more
wiley   +1 more source

Synthesis of the Proposed Structure of Celacarfurine and Analogues Using Sequential Cascade Ring Expansion Reactions. [PDF]

open access: yesOrg Lett
Tam JKF   +8 more
europepmc   +1 more source

Mechanochemical SNAr on Phthalonitriles: Distinct Reactivity and Selectivity in One‐Pot Synthesis for Greener Phthalocyanines

open access: yesChemSusChem, Volume 19, Issue 11, 15 June 2026.
Mechanochemical nucleophilic aromatic substitution enables efficient, reproducible functionalization of phthalonitriles under minimal solvent conditions with high versatility. Integrating this process with solid‐state cyclotetramerization affords metalated and metal‐free phthalocyanines in a streamlined sustainable one‐pot workflow.
Obed Rodriguez‐Perez   +3 more
wiley   +1 more source

Toward Larger Cyclo‐9,10‐Anthryleneparaphenylenes

open access: yesChemistry – A European Journal, Volume 32, Issue 22, 9 June 2026.
During a macrocyclization with a dihydroanthracene diol as corner unit, larger oligomers than the trimer and tetramer were formed and isolated up to the nonamer. Their three‐dimensional structures were studied by X‐ray diffraction. The most abundant macrocycles were rearomatized to the corresponding CPP derivatives.
Moritz P. Schuldt   +3 more
wiley   +1 more source

Alcohol‐Directed Carboamination of Conjugated Enynes

open access: yesAngewandte Chemie, Volume 138, Issue 24, 8 June 2026.
The first general three‐component intermolecular Pd‐catalyzed carboamination of conjugated enynes enables the coupling of anilines and aryl triflates to produce functionalized allenic amines, utilizing a native alcohol directing group to control regioselectivity.
Helena Solé‐Àvila   +3 more
wiley   +1 more source

Acridane[4]Arenes: Scope of the Macro-Tetramerization, Derivatization Options, and Water-Soluble Derivatives. [PDF]

open access: yesChemistry
Höft V   +4 more
europepmc   +1 more source

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