Topologically Engineering of π-Conjugated Macrocycles: Tunable Emissions and Photochemical Reactions [PDF]
, 2022 The topology of conjugated macrocycles had significant impacts on their photo-physical and photo-chemical properties. Herein, a series of π-conjugated macrocycles with diverse topology were synthesized via intramolecular McMurry coupling.
Lei, Wang +9 more
core +1 more source
Pathway Complexity in the Stacking of Imine-linked Macrocycles Related to Two-Dimensional Covalent Organic Frameworks [PDF]
, 2019 This work reports on the assembly of imine-linked macrocycles that serve as models of two-dimensional covalent organic frameworks (2D COFs). Interlayer interactions play an important role in the formation of 2D COFs, yet the effect of monomer structure ...
Chao, Sun +10 more
core +1 more source
Functional Group Introduction and Aromatic Unit Variation in a Set of π-Conjugated Macrocycles: Revealing the Central Role of Local and Global Aromaticity [PDF]
, 2021 π-Conjugated macrocycles are molecules with unique properties that are increasingly exploited for applications and the question of whether they can sustain global aromatic or antiaromatic ring currents is particularly intriguing.
Florian, Glöcklhofer +6 more
core +1 more source
Symmetric Macrocycles by a Prins Dimerization and Macrocyclization Strategy [PDF]
Organic Letters, 2009 A tandem dimerization/macrocyclization reaction utilizing the Prins cyclization has been developed. This reaction develops molecular complexity through the formation of highly substituted dimeric tetrahydropyran macrocycles. Mild conditions utilizing rhenium(VII) catalysts were explored for aromatic substrates, while harsher Lewis acidic conditions ...
Michael R, Gesinski +2 more
openaire +2 more sources
Nature Communications, 2022 Macrocycles have potential as therapeutics, but their libraries are currently not large enough for high-throughput screening. Here, the authors show a combinatorial approach to generate a library of almost 20’000 macrocycles by conjugating carboxylic ...
Sevan Habeshian +12 more
doaj +1 more source
Tetraruthenium Metallamacrocycles with Potentially Coordinating Appended Functionalities
Inorganics, 2018 We present four new tetraruthenium macrocycles built from two 1,4-divinylphenylene diruthenium and two isophthalic acid building blocks with peripheral, potentially mono- or tridentate donor functions attached to the isophthalic linkers.
Patrick Anders +3 more
doaj +1 more source
Antimicrobial Activity of Calixarenes and Related Macrocycles
Molecules, 2020 Calixarenes and related macrocycles have been shown to have antimicrobial effects since the 1950s. This review highlights the antimicrobial properties of almost 200 calixarenes, resorcinarenes, and pillararenes acting as prodrugs, drug delivery agents ...
Dmitriy N. Shurpik +3 more
doaj +1 more source
Cooperative Self-Assembly of Pyridine-2,6-Diimine-Linked Macrocycles into Mechanically Robust Nanotubes [PDF]
, 2019 Nanotubes assembled from macrocyclic precursors offer a unique combination of low dimensionality, structural rigidity, and distinct interior and exterior microenvironments. Usually the weak stacking energies of macrocycles limit the length or strength of
Chao, Sun +7 more
core +1 more source
Nanoarchitectonics of Exfoliated Flexible Nanosheet Based on Laterally Stacked Macrocycles
Advanced Materials Interfaces, 2023 2D nanostructures including monolayers and few layers exhibit unique properties originating from the anisotropic ultrathin nature. Conventional organic 2D nanostructures, such as covalent organic frameworks, are comprised of the planar π‐conjugated ...
Nano Shioda +5 more
doaj +1 more source
Design of indole- and MCR-based macrocycles as p53-MDM2 antagonists
Beilstein Journal of Organic Chemistry, 2019 Macrocycles were designed to antagonize the protein–protein interaction p53-MDM2 based on the three-finger pharmacophore F19W23L25. The synthesis was accomplished by a rapid, one-pot synthesis of indole-based macrocycles based on Ugi macrocyclization ...
Constantinos G. Neochoritis +7 more
doaj +1 more source