Results 71 to 80 of about 25,345 (208)
Journal of Nucleic Acids, 2010 A collection of 26 polyammonium cyclophane-type macrocycles with a large structural diversity has been screened for G-quadruplex recognition. A two-step selection procedure based on the FRET-melting assay was carried out enabling identification of ...
Anton Granzhan +5 more
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Diaquabromidocopper(II)–18-crown-6–water (1/1/2)
Acta Crystallographica Section E, 2010 In the title compound, [CuBr2(H2O)2]·C12H24O6·2H2O, the CuII atom, which is situated on an inversion centre and has a slightly distorted square-planar geometry, and the two coordinated water molecules are linked to the 18-crown-6 ...
Bo Wang
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1,2,3-Triazolium macrocycles in supramolecular chemistry
Beilstein Journal of Organic Chemistry, 2019 In this short review, we describe different pathways for synthesizing 1,2,3-triazolium macrocycles and focus on their application in different areas of supramolecular chemistry.
Mastaneh Safarnejad Shad +2 more
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Conformationally Restricted Macrocycles as Improved FKBP51 Inhibitors Enabled by Systematic Linker Derivatization [PDF]
Macrocycles are increasingly considered as promising modalities to target challenging intracellular proteins. However, strategies for transitioning from active linear starting points to improved macrocycles are still underdeveloped.
Bauder, Michael +8 more
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Macrocycle-Based Supramolecular Drug Delivery Systems: A Concise Review
MoleculesEfficient delivery of therapeutic agents to the lesion site or specific cells is an important way to achieve “toxicity reduction and efficacy enhancement”. Macrocycles have always provided many novel ideas for drug or gene loading and delivery processes.
Yanrui Yang +5 more
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High-Efficiency Non-Thermal Plasma Synthesis of Imine Macrocycles [PDF]
Macrocycles are candidates for wide-ranging applications, yet their synthesis can be low-yielding, poorly reproducible, and resource-intensive, limiting their use.
Timothy L, Easun +4 more
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Molecules, 2013 Macrocyclic hexaoxazole dimer of L2H2-6OTD-dimer (3) was newly synthesized as a telomeric G-quadruplex (G4) ligand, and interaction with long telomeric DNAs telo48, 72, and 96 was evaluated by means of electrophoresis mobility shift assay, CD spectra ...
Kazuo Nagasawa +4 more
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Aromatic Oligoamide Macrocycles with a Backbone of Reduced Constraint
, 2016 Oligoamide macrocycles with a backbone partially constrained by hydrogen bonds have been prepared. These macrocycles, carrying multiple H-bonding side chains, underwent strong aggregation in solution and form long fibers in the solid state.
Mark Kline (1909393) +2 more
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Phosphoramidite derivatives of macrocycles [PDF]
, 1997 The invention is directed to phosphoramidite derivatives of macrocycles, such as porphyrins and expanded porphyrins, including sapphyrins and texaphyrins.
Magda, Darren +2 more
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New linked macrocyclic systems derived from selectively protected S2N2 macrocycles
, 1996 Novel application of a protecting group strategy has enabled a simple and efficient synthesis of the new tri-linked S2N2 macrocycles 12, 15, 17 and 20.
Leonard F. Lindoy and George V. Meehan +1 more
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