Results 71 to 80 of about 21,344 (285)

Macrocyclic Compounds Comprising Tris(3-Aminopropyl)Amine Units and Fluorophore Moieties: Synthesis and Spectroscopic Studies in the Presence of Metal Salts

Chemosensors, 2023
The synthesis of a variety of polyazamacrocyclic compounds comprising structural units of tris(3-aminopropyl)amine (TRPN) and oxadiamines, decorated with one or two fluorophore groups (dansyl or quinoline) at different nitrogen atoms, was carried out ...
Daria S. Kuliukhina, Nataliya M. Chernichenko, Alexei D. Averin, Anton S. Abel, Olga A. Maloshitskaya, Irina P. Beletskaya   +5 more
doaj   +1 more source

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

Advanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu, Tiancheng Li, Yu Jin, Yixin Li, Qicheng Liu, Runzhe Fang, Luyao Qu, Xinyue Tang, Ruomei Li, Xiaoyue Zhao, Jin Hao, Bing Fang, Lunguo Xia   +12 more
wiley   +1 more source

New linked macrocyclic systems derived from selectively protected S2N2 macrocycles [PDF]

, 1996
Novel application of a protecting group strategy has enabled a simple and efficient synthesis of the new tri-linked S2N2 macrocycles 12, 15, 17 and 20.
Leonard F. Lindoy and George V. Meehan, Andrew M. Groth   +1 more
core  

Synthesis of Two 2,2′-Bipyridine Containing Macrocycles for the Preparation of Interlocked Architectures [PDF]

, 2017
The synthesis and characterisation of two 28-membered, 2,2′-bipyridine-containing macrocycles in high yield is reported. The first imine-containing macrocycle was formed via a Williamson ether synthesis and showed no evidence of higher oligomer formation.
Cremers, Jonathan, Jacob Whittaker, Jason R. Price, Price, Jason R., John C. McMurtrie, Whittaker, Jacob, McMurtrie, John C., Jack K. Clegg, Suresh Moorthy, Moorthy, Suresh, Jonathan Cremers, Clegg, Jack K.   +11 more
core   +1 more source

Generation of the Camptothecin Scaffold by a Flavin‐Catalyzed Photooxidative Skeletal Reorganization

Angewandte Chemie, EarlyView.
The biosynthetic pathway of the anticancer drug precursor camptothecin involves an enigmatic skeletal reorganization from a 6/5/6 tetrahydro‐β‐carboline to a 6/6/5 pyrroloquinoline ring system. Here, we show that this transformation can be achieved by photooxidation with flavin cofactors, such as flavin mononucleotide (FMN) as catalysts.
Shenyu Liu, Zeliang Zhang, Benedikt Seligmann, Van Hung Bui, Tuan‐Anh Minh Nguyen, Thu‐Thuy T. Dang, Jakob Franke   +6 more
wiley   +2 more sources

A STRAIGHTFORWARD SYNTHESIS OF NOVEL 1,3,5-TRIAZINE-BASED MACROCYCLIC SCAFFOLDS

Studia Universitatis Babes-Bolyai Chemia, 2020
The synthesis and structural investigation of a series of three macrocycles bearing 2,4,6-tris(p-phenylene)-1,3,5-triazine central units and oligoethyleneoxide bridges are reported.
Cosmin V. CRIŞAN, Niculina D. HĂDADE, Ion GROSU, Andreea P. CRIŞAN, Anamaria TEREC   +4 more
doaj   +1 more source

Inner-bond-cleavage approach to figure-eight macrocycles from planar aromatic hydrocarbons [PDF]

Contemporary synthetic strategies in organic chemistry rely heavily on the stepwise formation of bonds between fragments of the target compound (‘bottom-up’ approach). Figure-eight aromatic macrocycles represent a considerable challenge for the bottom-up
Reiji , Yoshina, Guanting , Liu, Junichiro , Hirano, Eiji , Yashima, Akinori , Saeki, Emiko , Nishimoto, Jinseok , Kim, Norihito, Fukui, Juwon , Oh, Tomoyuki, Ikai, Shunsuke , Minabe, Dongho , Kim, Takuma , Yasuda, Hiroshi , Shinokubo, Takuya , Omine, Yuki , Sakamoto, Fumitaka, Ishiwari, Keita , Tajima, Muhammet , Uyanik, Kazuaki , Ishihara   +19 more
core   +1 more source

Multicomponent Syntheses of Macrocycles [PDF]

, 2010
How to access efficiently the macrocyclic structure remained to be a challenging synthetic topic. Although many elegant approaches/reactions have been developed, construction of diverse collection of macrocycles is still elusive.
Jieping Zhu, Luc Neuville, Neuville, L., Burghin, Carine, Fayol, Audie, Aude Fayol, Masson, G., Géraldine Masson, Zhu, Jieping, Zhu, J., Carine Bughin, Fayol, A., Masson, Géraldine, Neuville, Luc, Bughin, C.   +14 more
core   +1 more source

Harnessing the Reactivity of Sulfinate Salts With Cystine: An Umpolung Approach to Residue‐Specific Peptide Modification

Angewandte Chemie, EarlyView.
While cysteine is widely employed as a nucleophilic handle for peptide modification, the electrophilicity of the oxidized form, cystine, is rarely exploited. This study describes a mild, photochemical coupling of sulfinate salts with peptide disulfides.
Joshua M. Hammond, Esteban Suárez‐Picado, Lena von Sydow, Hanna Bruss, Laurent Knerr, Magnus Johansson, Anaïs Noisier, Lara R. Malins   +7 more
wiley   +2 more sources

Tailoring High‐Valent Iron‐Oxo Species Redox via Extended π‐Fe3d–O2p Orbital Overlapping Toward Chemical‐Efficient Water Purification

Angewandte Chemie, EarlyView.
We address the long‐standing challenge of reactivity–selectivity trade‐off by precisely tuning the redox properties of Fe(IV), rather than simply accelerating its formation, to enable chemically efficient and low‐emission water treatment. ABSTRACT High‐valent iron oxo species (Fe(IV)) are attractive for wastewater treatment because of their high ...
Hongyu Zhou, Junwen Chen, Jiuyi Wang, Xinhao Wang, Qiming Zhang, Shiying Ren, Xuning Li, Li Gao, Shaobin Wang, Xiaoguang Duan   +9 more
wiley   +2 more sources