Results 71 to 80 of about 9,528 (245)
Quartz Microbalance Sensor for the Detection of Acrylamide
Sensors, 2004 : Several macrocycles of the Hunter-Vögtle type have been identified as superior host compounds for the detection of small amounts of acrylamide. When coated onto the surface of a quartz microbalance, these compounds serve as highly sensitive and ...
Christoph A. Schalley +4 more
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, 2014 Citation: 'macrocycle' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.M03662 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +2 more sources
A membrane permeability database for nonpeptidic macrocycles
Scientific DataThe process of developing new drugs is arduous and costly, particularly for targets classified as “difficult-to-drug.” Macrocycles show a particular ability to modulate difficult-to-drug targets, including protein-protein interactions, while still ...
Qiushi Feng +3 more
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Beilstein Journal of Organic Chemistry, 2014 Natural product-like macrocycles were designed as potential antibacterial compounds. The macrocycles featured a D-glucose unit fused into a 12- or 13-member macrolactone.
Richard T. Desmond +5 more
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Journal of Nucleic Acids, 2010 A collection of 26 polyammonium cyclophane-type macrocycles with a large structural diversity has been screened for G-quadruplex recognition. A two-step selection procedure based on the FRET-melting assay was carried out enabling identification of ...
Anton Granzhan +5 more
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Diaquabromidocopper(II)–18-crown-6–water (1/1/2)
Acta Crystallographica Section E, 2010 In the title compound, [CuBr2(H2O)2]·C12H24O6·2H2O, the CuII atom, which is situated on an inversion centre and has a slightly distorted square-planar geometry, and the two coordinated water molecules are linked to the 18-crown-6 ...
Bo Wang
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Toward Chromoselective Transformations in Biological Systems: Perspectives and Challenges
Angewandte Chemie International Edition, EarlyView.Controlling biological systems with small‐molecule chromophores has evolved into a powerful strategy and is applied from chemical biology to medicine. However, the complexity of in vivo systems cannot be matched by a single wavelength of light. Developing methods to combine and individually control multiple chromophores is crucial.
Nadja A. Simeth
wiley +1 more source
1,2,3-Triazolium macrocycles in supramolecular chemistry
Beilstein Journal of Organic Chemistry, 2019 In this short review, we describe different pathways for synthesizing 1,2,3-triazolium macrocycles and focus on their application in different areas of supramolecular chemistry.
Mastaneh Safarnejad Shad +2 more
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Macrocycle-Based Supramolecular Drug Delivery Systems: A Concise Review
MoleculesEfficient delivery of therapeutic agents to the lesion site or specific cells is an important way to achieve “toxicity reduction and efficacy enhancement”. Macrocycles have always provided many novel ideas for drug or gene loading and delivery processes.
Yanrui Yang +5 more
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Drug Discovery Today: Technologies, 2018 Macrocycles are an emerging and largely underexploited part of chemical space where potential drugs for difficult genomic targets can be discovered. Macrocycles can have advantages over their natural twins such as better control over synthesis, physicochemical properties and target binding.
Abdelraheem, Eman M.M. +2 more
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