Results 21 to 30 of about 1,721,261 (283)
Synthetic Receptors for Early Detection and Treatment of Cancer
Over recent decades, synthetic macrocyclic compounds have attracted interest from the scientific community due to their ability to selectively and reversibly form complexes with a huge variety of guest moieties. These molecules have been studied within a
Frank Davis, Séamus P. J. Higson
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Macrocyclic Arenes Functionalized with BODIPY: Rising Stars among Chemosensors and Smart Materials
Macrocycles play a crucial role in supramolecular chemistry and the family of macrocyclic arenes represents one of the most important types of hosts. Among them, calixarenes, resorcinarenes and pillararenes are the most commonly encountered macrocyclic ...
Jianjun Huang, Yuyu Fang, Wim Dehaen
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Synthesis of functionalized macrocyclic derivatives of trioxabicyclo[3.3.0]nonadiene
C72-Macrocyclic systems functionalized with nitroaryl and arylamino groups were synthesized from the bisdioxine diacid dichloride 1,3,5,7-tetra-tert-butyl-2,6,9-trioxabicyclo[3.3.1]nona-3,7-diene-4,8-dicarbonyl dichloride (3).
Sabine Leber, Gert Kollenz, Curt Wentrup
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Structural Features and Binding Modes of Thioether-Cyclized Peptide Ligands
Macrocyclic peptides are an emerging class of bioactive compounds for therapeutic use. In part, this is because they are capable of high potency and excellent target affinity and selectivity. Over the last decade, several biochemical techniques have been
Manuel E. Otero-Ramirez +2 more
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Progress in the Chemistry of Macrocyclic Meroterpenoids
In the last decade, the chemistry of meroterpenoids—conjugated molecules formed from isoprenyl fragments through biosynthetic pathways—has developed rapidly.
Dmitriy N. Shurpik +4 more
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Performance evaluation of flexible macrocycle docking in AutoDock
Macrocycles represent an important class of ligands, both in natural products and designed drugs. In drug design, macrocyclizations can impart specific ligand conformations and contribute to passive permeation by encouraging intramolecular H-bonds ...
Matthew Holcomb +3 more
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Cyclic and Macrocyclic Organic Compounds - a Personal Review in Honor of Professor Leopold Ružička [PDF]
Ružička opened the field of cyclic molecules such as cyclic terpenes and cyclic ketones with up to 17 ring atoms. This work until now was extended in many directions such as cyclic paraffins, crown ethers and cryptands and cyclic ester amides.
Höcker¸, H.
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