The synthesis, isolation, and purification of enzymatic substrates were achieved by an eleven-step enantioselective synthesis, which included the Crimmins asymmetric aldol reaction and its corresponding acetate aldol reaction.
Caissie, Alyssa A.
core
A CONVENIENT SYNTHESIS OF MACROCYCLIC DIAMIDES [PDF]
Some new macrocyclic dibenzotrioxadiamides, dibenzotetraoxadiamide, dibenzopentaoxadiamide, dibenzothiatrioxadiamide, tribenzotrioxadiamides and tetrabenzohexaoxadiamide (14-21), (26) and (27) have been prepared.
doaj
Macrocyclization of 2-(5-(2-hydroxyethyl)furan-2-yl)acetic acid model compounds of nonactic acid
A method for the synthesis of macrocyclic compds. is reported here. The macrocyclization of (hydroxyethyl)furanacetic acid and of dehydrogenated model compds. of nonactic acid was investigated to develop a facile synthesis of nonactin analogs.
Simone, Jean-Mary +4 more
core +1 more source
The Role of Attractive Non-Covalent Interactions in Peptide Macrocyclization
The efficiency of macrocyclization reactions relies on the appropriate conformational preorganization of a linear precursor, ensuring that reactive ends are in spatial proximity prior to ring closure.
George J. Saunders (17783983) +4 more
core +1 more source
Convergent Synthesis of the Minimal Macrolide Antibiotic Narbomycin. [PDF]
Edmondson Q +5 more
europepmc +1 more source
Organometallic Chemistry Approach to Peptide Tricycles. [PDF]
Adhami N +16 more
europepmc +1 more source
Investigating Topological Parameters in Polymers: Precision Synthesis of Trefoil Polymers from a Knotted Synthon. [PDF]
Deng J, Jiang X, Qiu Y.
europepmc +1 more source
Inverted metal-free active template synthesis of rotaxanes via axle‑mediated macrocyclization. [PDF]
Zhong J +7 more
europepmc +1 more source
Tetrazine-Enabled Peptide Macrocyclization and Bioorthogonal Cell Penetration Profiling. [PDF]
Liu H +12 more
europepmc +1 more source
Unified Access to Biaryl-Bridged Linkages Unlocks Structural Diversification of Noncanonical Cyclic Peptides. [PDF]
Yu L +8 more
europepmc +1 more source

