Results 41 to 50 of about 3,332 (181)
Self-cyclisation as a general and efficient platform for peptide and protein macrocyclisation
Communications Chemistry, 2023 Head-to-tail macrocyclization of proteins and peptides can increase their structural stability, however, potential polymerization can lead to reduced yields.
Xinying Jia +10 more
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Macrocyclic coordination chemistry [PDF]
Annual Reports Section "A" (Inorganic Chemistry), 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Archibald, Steve, Archibald, Stephen J.
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Total Synthesis and Pharmacological Investigation of Cordyheptapeptide A
Molecules, 2017 The present investigation reports the synthesis of a phenylalanine-rich N-methylated cyclopeptide, cordyheptapeptide A (8), previously isolated from the insect pathogenic fungus Cordyceps sp.
Suresh Kumar +5 more
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Late‐Stage Functionalization of Peptides on the Solid Phase
Angewandte Chemie International Edition, EarlyView.Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner +2 more
wiley +1 more source
A Revised Model for Muscarine Biosynthesis Involving Lysine Trimethylation
Angewandte Chemie, Volume 138, Issue 24, 8 June 2026.The fatal mushroom toxin l‐(+)‐muscarine is one of the most prominent natural products. We elucidated its biosynthetic origin in the sweating mushroom Collybia rivulosa based on incorporation of stable isotope‐labeled compounds and extensive mass spectrometric analyses.
Sebastian Dörner +4 more
wiley +2 more sources
Nature Communications, 2022 Macrocyclization is an important process in bioactive natural product synthesis. Here, the authors report on the study of a macrocyclic ring constructing enzyme in the biosynthesis of alchivemycin A and using gene deletion, biochemical assays and isotope
Hong Jie Zhu +11 more
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Thiol-Yne click chemistry of acetylene-enabled macrocyclization
Nature Communications, 2022 Thiol–yne coupling is a reliable method to link two molecular units, but has not been extensively explored for the construction of macrocycles. Here, the authors use gaseous acetylene, the simplest alkyne unit, to synthesize a variety of macrocycles ...
Shiwei Lü, Zipeng Wang, Shifa Zhu
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Recent Advances in Macrocyclic and Macrocyclic-Based Anion Receptors
Supramolecular Chemistry, 2008 The interest in anion coordination chemistry has growth enormously in the last few years. Macrocyclic and macrocyclic-based architectures are at the forefront of the development of new anion receptors. This minireview is intended to illustrate some of the goals achieved recently in this field highlighting examples appeared in the literature over the ...
Pilar Prados, Roberto Quesada
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Macrocyclic ligands on polymers [PDF]
Pure and Applied Chemistry, 1979 Abstract The ion binding properties of linear polymers carrying crown ether ligands as pendent groups are reviewed. The polymers often exhibit selective cation binding different from that of their monomeric crown analogues. One of the polymers, poly(vinylbenzo-18-crown-6), behaves in water as a neutral polysoap and strongly interacts with organic ...
J. Smid +4 more
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Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview
Chemistry – A European Journal, EarlyView.The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati +4 more
wiley +1 more source