Results 61 to 70 of about 3,332 (181)
Revisit to ()-Civetone Synthesis
Natural Product Communications, 2012 The synthesis of ( Z )-civetone ( 1 ) is described starting from oleic acid ( 5 ) via a series of reactions, intermolecular olefin self-metathesis, bromination/dehydrobromination into acetylene, semi-hydrogenation and intramolecular Dieckmann ...
Hisahiro Hagiwara +4 more
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Nature Communications, 2017 Cyclic peptide macrocycles are promising anti-cancer and antimicrobial molecules. Here, the authors characterize the structure and catalytic mechanism of the prolyl oligopeptidase B from Basidiomycete fungi, showing that its dual macrocyclase-peptidase ...
Clarissa M. Czekster +3 more
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Advanced Science, Volume 13, Issue 31, 4 June 2026.Segmental‐level molecular engineering of a supramolecular polyurethane elastomer integrates strain‐adaptive chains, soft elastic segments, and dynamic hydrogen bonding motifs. This design reconciles skin‐like softness with muscle‐level strength, offering a sustainable and high‐performance material platform for next‐generation artificial skin and soft ...
Haoming Zou +5 more
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, 2014 Citation: 'macrocycle' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.M03662 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
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Synthesis of Monothiacalix[4]arene Using the Fragment Condensation Approach
MoleculesThe article describes a simple and scalable preparation of 2-monothiacalix[4]arene 7, the simplest representative of the mixed-bridged (CH2 and S) calix[4]arenes.
Daniel Kortus +7 more
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CHIMIA, 2011 Macrocyclization methodologies allowing access to macrocycles having an endo aryl ether and an endo aryl–aryl bond, especially those based on an intramolecular SNAr reaction and the Suzuki-Miyaura reaction, are summarized.
Qian Wang, Jieping Zhu
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A Short Synthesis of Cyclo(‐RGDfK) Using a Microflow Reactor
ChemistryEurope, Volume 4, Issue 6, June 2026.An efficient synthesis of cyclo(‐RGDfK) was achieved by combining a one‐flow three‐component coupling (3CC) reaction via α‐amino acid N‐carboxy anhydrides with rapid macrolactamization using a microflow reactor. Precise control of the water content and base loading in the 3CC reaction enabled the gram‐scale synthesis of the desired tripeptides and ...
Naoto Yamasaki +6 more
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Beilstein Journal of Organic Chemistry, 2014 In this review, we describe direct and indirect photochemical approaches that have been developed for the preparation of phthalimide- and naphthalimide-based, lariat-type crown ethers.
Dae Won Cho +2 more
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Case Studies of the Synthesis of Bioactive Cyclodepsipeptide Natural Products
Molecules, 2013 Cyclodepsipeptide natural products often display intriguing biological activities that along with their complex molecular scaffolds, makes them interesting targets for chemical synthesis.
Markus Kaiser, Sara C. Stolze
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Drug Discovery Today: Technologies, 2018 Macrocycles are an emerging and largely underexploited part of chemical space where potential drugs for difficult genomic targets can be discovered. Macrocycles can have advantages over their natural twins such as better control over synthesis, physicochemical properties and target binding.
Abdelraheem, Eman M.M. +2 more
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