Results 31 to 40 of about 88,400 (300)

Macrolide resistance and susceptibility in Mycobacterium tuberculosis.

open access: yes, 2004
Macrolide resistance and susceptibility in Mycobacterium ...
Kanakeshwari. Falzari (7985453)
core   +4 more sources

Pharmacokinetics of Azalomycin F, a Natural Macrolide Produced by Streptomycete Strains, in Rats

open access: yesMolecules, 2021
As antimicrobial resistance has been increasing, new antimicrobial agents are desperately needed. Azalomycin F, a natural polyhydroxy macrolide, presents remarkable antimicrobial activities. To investigate its pharmacokinetic characteristics in rats, the
Su He   +7 more
doaj   +1 more source

Exacerbation Prevention and Management of Bronchiectasis [PDF]

open access: yesTuberculosis and Respiratory Diseases, 2023
Bronchiectasis, which is characterized by irreversibly damaged and dilated bronchi, causes significant symptoms, poor quality of life, and increased economic burden and mortality rates.
Joon Young Choi
doaj   +1 more source

Noncanonical Peloruside A Biosynthesis by an Uncultivated Verrucomicrobiota Symbiont

open access: yesAngewandte Chemie, EarlyView.
Noncanonical biochemistry of the peloruside PKS characterized in this work, comprising double bond generation by a noncanonical tridomain (blue), acetyl‐CoA recycling (orange), and proofreading systems (purple and yellow). The Z‐double bond is installed by TEB1 through O‐acetylation and acetate elimination. The acyl ligase PelB (AL, orange) selectively
Amy E. Fraley   +11 more
wiley   +2 more sources

The Effect of Antibiotics on the Infant Gut Fungal Microbiota

open access: yesJournal of Fungi, 2022
Antibiotics are commonly used drugs in infants, causing disruptions in the developing gut microbiota with possible detrimental long-term effects such as chronic inflammatory diseases.
Rebecka Ventin-Holmberg   +7 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Characterization of a Fungal Modular Polyketide Synthase System Reveals an Unusual Strategy for Polyketide Chain Initiation

open access: yesAngewandte Chemie, EarlyView.
Fungal modular polyketide synthases (PKSs) remain largely unexplored. Functional characterization of the LasC/LasD assembly line established its role in strasseriolide C biosynthesis and suggested an unexpected strategy for chain initiation, in which a malonyl unit is transferred from the module 2 acyl carrier protein (ACP) domains to the loading ACP ...
Qiaolin Ji   +5 more
wiley   +2 more sources

Occurrence and Removal of Macrolides in Municipal Wastewater Treatment Plants: A Review

open access: yesJournal of Environmental Health and Sustainable Development, 2021
Introduction: Macrolides are a group of antibacterial agents. Given their clinical importance, and the consistent rise in resistance among pathogenic bacteria, macrolides have been the targets of extensive research.
Zahra Abbasi, Mehdi Ahmadi
doaj  

Effects of Phytotoxic Nonenolides, Stagonolide A and Herbarumin I, on Physiological and Biochemical Processes in Leaves and Roots of Sensitive Plants

open access: yesToxins, 2023
Phytotoxic macrolides attract attention as prototypes of new herbicides. However, their mechanisms of action (MOA) on plants have not yet been elucidated. This study addresses the effects of two ten-membered lactones, stagonolide A (STA) and herbarumin I
Elena V. Tyutereva   +8 more
doaj   +1 more source

Macrolide‐resistant Mycoplasma pneumoniae pneumonia in transplantation: Increasingly typical? [PDF]

open access: yes, 2020
Mycoplasma pneumoniae is one of the most common bacterial causes of pneumonia. Macrolide‐resistant M pneumoniae (MRMP) was documented in 7.5% of isolates in the United States.
Amy E. Ratliff   +15 more
core   +1 more source

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