Results 61 to 70 of about 88,400 (300)

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

Animal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen, Xiangfang Tang, Yimin Zhuang, Shengjun Zhao, Ying Ren, Xiaokang Lv   +5 more
wiley   +1 more source

Ceftriaxone‐induced liver injury: Incidence, phenotypic characterization and predictive factors

British Journal of Clinical Pharmacology, EarlyView.
Introduction Ceftriaxone is a widely used third‐generation cephalosporin in hospitalized patients. Although generally considered safe, it has been associated with hepatobiliary complications and emerging reports of drug‐induced liver injury (DILI). However, data on its true incidence, phenotypic patterns, and predictors remain limited. This study aimed
Mohamed Hatem, Mohannad N. AbuHaweeleh, Humam Emad Rajha, Mhd Osama Rahhal, Ahmad Hamdan, Lina Naseralallah   +5 more
wiley   +1 more source

Macrolide- and telithromycin-resistant **Streptococcus pyogenes**, Belgium, 1999-2003 [PDF]

, 2005
: We found a 13% macrolide resistance in 3,866 Streptococcus pyogenes isolated from tonsillopharyngitis patients: 59% macrolide-resistant isolates were distributed in 5 clones, suggesting the importance of both resistance gene transfer and clonal ...
Piessens, Jasper, Surbhi Malhotra-Kumar, Chapelle, Sabine, Jasper Piessens, Christine Lammens, Herman Goossens, Goossens, Herman, Lammens, Christine, Monique Wijdooghe, Wijdooghe, Monique, Koen Van Herck, Sabine Chapelle, van Herck, Koen, Malhotra-Kumar, Surbhi   +13 more
core   +1 more source

Unsupervised machine learning for multi‐system adverse event pattern detection in pharmacovigilance: A proof‐of‐concept analysis of fluoroquinolone reports in FAERS

British Journal of Clinical Pharmacology, EarlyView.
. Aims Traditional pharmacovigilance detects single drug–event associations but cannot readily characterize multi‐system adverse‐event patterns such as fluoroquinolone‐associated disability. We evaluated unsupervised machine learning for this purpose, using fluoroquinolones as an exemplar.
Niaz Chalabianloo, Sheikh S. Abdullah, Kamran Sedig, Flory T. Muanda   +3 more
wiley   +1 more source

Interface‐Engineered MXene/g‐C3N4 Heterostructures for Energy and Environmental Applications

EcoEnergy, EarlyView.
This review highlights how interface engineering in MXene/g‐C3N4 heterostructures regulates charge transfer, band alignment, and surface chemistry, enabling broad applications in photocatalytic conversion, environmental remediation, energy storage, and multifunctional sensing/therapy. ABSTRACT Two‐dimensional MXene/g‐C3N4 heterostructures have recently
Feng Wang, Geng Liu, Xiaoqiang An
wiley   +1 more source

Dissecting erm (41)-Mediated Macrolide-Inducible Resistance in Mycobacterium abscessus

, 2020
International audienceMacrolides are the cornerstone of Mycobacterium abscessus multidrug therapy, despite that most patients respond poorly to this class of antibiotics due to the inducible resistance phenotype that occurs during drug treatment.
Richard, Matthias, Kremer, Laurent, Gutiérrez, Ana Victoria   +2 more
core   +1 more source

Phenotypes and genotypes of macrolide-resistant Streptococcus pneumoniae in Serbia [PDF]

, 2014
Although macrolides are widely used for treating pneumococcal infections, an increase in macrolide resistance might compromise their use. The objective of this study was to determine the prevalence of macrolide-resistant phenotypes and genotypes
Natasa Opavski, Považan Anika, Opavski Nataša, Vulin Aleksandra, Mijac Vera, Ina Gajic, Mirjana Hadnadjev, Vera Mijac, Anika Povazan, Tatjana Kurucin, Aleksandra Vulin, Gajić Ina, Hadnađev Mirjana, Kurucin Tatjana   +13 more
core   +2 more sources

Synthetic Strategies for the Construction of Cyclobutane‐Fused Heterocycles

European Journal of Organic Chemistry, EarlyView.
Cyclobutane‐fused heterocycles are important motifs commonly present in bioactive compounds, recognized for their rigid 3D structures that confer unique properties. However, synthesizing these compounds remains challenging. This review discusses current methods for their synthesis, such as photochemical, metal‐catalyzed, and Lewis acid‐mediated [2 + 2]
Michela Vargiu, Mauro Uras, Angelo Frongia   +2 more
wiley   +1 more source

Macrolide Antibiotic Mediated Cardiac Arrhythmias: Emerging Concepts and Clinical Implications

Biomedicines
The macrolide class of antibiotics are widely utilized in clinical settings for a broad range of bacterial infections and have additional roles as immunomodulatory agents. Although efficacious with a good safety profile overall, they have been associated
Fatima Iqbal, Alyssa Derouen, Robin Ren, Adam M. Kaye, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D. Kaye   +6 more
doaj   +1 more source