Results 121 to 130 of about 16,667 (258)

Contrasting effects of different molecular crowding environments on base‐pair opening/closing dynamics of DNA triplex structures

The FEBS Journal, EarlyView.
Base‐pair opening and closing regulate nucleic‐acid structure, stability, and function, but how these motions behave under intracellular molecular crowding remains unclear. Using NMR, we quantified these dynamics in a DNA triplex under two crowder‐reconstituted environments that mimic cellular crowding.
Tomoki Sakamoto, Yudai Yamaoki, Takashi Nagata, Masato Katahira   +3 more
wiley   +1 more source

An optimized strategy to measure protein stability highlights differences between cold and hot unfolded states

Nature Communications, 2017
Crowding effects—important when considering cellular environments—greatly influence protein stability. Here the authors study the impact of macromolecular crowders on high and low temperature protein unfolding, and show that volume exclusion effects are ...
Caterina Alfano, Domenico Sanfelice, Stephen R. Martin, Annalisa Pastore, Piero Andrea Temussi   +4 more
doaj   +1 more source

Effects of macromolecular crowding on protein folding [PDF]

, 2015
Phuong Thuy Bui, Hoang Thi Huong, Trịnh Xuân Hoàng   +2 more
openalex   +1 more source

Macromolecular crowding modulates α-synuclein amyloid fiber growth [PDF]

, 2021
István Horváth, Ranjeet Kumar, Pernilla Wittung‐Stafshede   +2 more
openalex   +1 more source

Phytohormonal and Transcriptomic Mechanisms of Multigenerational Stress Memory in Wheat Under Weed Competition

Plant, Cell &Environment, EarlyView.
ABSTRACT Multigenerational stress exposure induces stress memory in plants, influencing resource allocation, defence mechanisms, and productivity. Weed competition imposes both resource‐based (abiotic) and allelopathic (biotic) stress, engaging overlapping hormonal pathways.
Albert O. Kwarteng, Joseph C. Kuhl, Brenda M. Murdoch, Fangming Xiao, Albert T. Adjesiwor   +4 more
wiley   +1 more source

An Equilibrium Model for the Combined Effect of Macromolecular Crowding and Surface Adsorption on the Formation of Linear Protein Fibrils [PDF]

, 2015
Travis Hoppe, Allen P. Minton
openalex   +1 more source

The oral microbiota and periodontal health in orthodontic patients

Periodontology 2000, EarlyView.
Abstract The oral microbiota develops within the first 2 years of childhood and becomes distinct from the parents by 4 years‐of‐age. The oral microbiota plays an important role in the overall health/symbiosis of the individual. Deviations from the state of symbiosis leads to dysbiosis and an increased risk of pathogenicity.
Brandon W. Peterson, Geerten‐Has Tjakkes, Anne‐Marie Renkema, David J. Manton, Yijin Ren   +4 more
wiley   +1 more source

Reviewing the benefits and clinical outcomes of oral fibroblasts over mesenchymal stem cells for repairing periodontal defects during or after orthodontic tooth movement

Periodontology 2000, EarlyView.
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi, Eleni Mavrogonatou, Anton Sculean, Dimitris Kletsas, Martin Degen   +4 more
wiley   +1 more source

Macromolecular Condensates as Tunable Scaffolds for Bio‐Inspired Silica Hybrids

Angewandte Chemie, Volume 138, Issue 14, 27 March 2026.
Dense bio‐inspired silica formation is achieved by coupling polyamine liquid–liquid phase separation with pH‐dependent silica polymerization. Silicification within polyamine condensates, enables precise control over particle size, density, and morphology.
Protap Biswas, Lior Aram, Nitzan Livni, Roman Kamyshinsky, Nadav Elad, Michal Leskes, Assaf Gal   +6 more
wiley   +2 more sources

Liquid–Liquid Phase Separation in Viral Infection and Immunology

MedComm, Volume 7, Issue 4, April 2026.
LLPS organizes viral replication and antiviral immunity. Viruses hijack LLPS to form replication factories and evade immune sensors, while hosts assemble LLPS‐driven signaling hubs (e.g., MAVS, RIG‐I, and SGs) to amplify interferon responses. Targeting these condensate interfaces offers novel therapeutic strategies against infectious diseases ...
Jiuzhi Xu, Lan Bai, Bin Wang, Hai Song, Long Zhang, Fangfang Zhou   +5 more
wiley   +1 more source